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US4228009A Expired / Lapsed US ⏱️ 0.0 years remaining

Toroidal coil planet centrifuge

Assignee: United States Department of Health and Human Services
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Filing: 1979-06-04
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Granted: 1980-10-14
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Expires: 1999-06-04
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Abstract

Abstract An apparatus for countercurrent chromatography consisting of a coiled separation column which is rotated about the axis about which is it wound and the axis is also rotated about a main axis. The embodiments of the invention are based on the fact that the pattern of the centrifugal force field greatly changes with the ratio of the two radii of rotation and depending on the particular effect desired, the apparatus is configured to achieve the most effective force field to gain the effect. The separation column is a tube helix wound around a flexible core member which can be wound onto the coil holder in various orientations to further effect the desired results.

Inventors

  • 👤 Yoichiro Ito

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-03 01:14
CPC Classifications
B; B01; B01D; B01D11/00; B01D11/02; B01D11/0269; B01D11/0273; B01D21/00; B01D21/26; B01D21/265; G; G01; G01N; G01N30/00; G01N30/02; G01N30/26; G01N30/38; G01N30/42

Claims Analysis

Total Claims: 14
Claim 1
Independent Claim 204 words
A toroidal coil planet centrifuge, comprising: a support means provided with upper and lower stationary members; rotary frame means provided with upper and lower plate portions and mounted between said stationary members for rotation about a first vertical axis; at least one coil means mounted between said upper and lower plate members around a second vertical axis, said second vertical axis being spaced from said first vertical axis by distance R, and said coil holder means having a substantially cylindrical separation column supporting surface spaced from said second axis by distance r, the ratio of r to R being greater than 0.25; separation column means mounted on said coil holder supporting surface, said separation column means including a flexible core member and at least one tube having ends at least one tube wound in a helix about said flexible core member; inlet and outlet tubes connected to respective said ends of said at least one tube; tube holding means located within said rotary frame means for holding said inlet and outlet tubes so that the orientation thereof remains constant; drive means for rotating said frame means and said coil holder means; and counterbalancing means mounted on said frame means opposite said coil holder means.
Claim 2
Dependent Claim 204 words
A toroidal coil planet centrifuge, comprising: a support means provided with upper and lower stationary members; rotary frame means provided with upper and lower plate portions and mounted between said stationary members for rotation about a first vertical axis; at least one coil means mounted between said upper and lower plate members around a second vertical axis, said second vertical axis being spaced from said first vertical axis by distance R, and said coil holder means having a substantially cylindrical separation column supporting surface spaced from said second axis by distance r, the ratio of r to R being greater than 0.25; separation column means mounted on said coil holder supporting surface, said separation column means including a flexible core member and at least one tube having ends at least one tube wound in a helix about said flexible core member; inlet and outlet tubes connected to respective said ends of said at least one tube; tube holding means located within said rotary frame means for holding said inlet and outlet tubes so that the orientation thereof remains constant; drive means for rotating said frame means and said coil holder means; and counterbalancing means mounted on said frame means opposite said coil holder means.
Claim 3
Dependent Claim 30 words
A centrifuge as in claim 1, wherein said counterbalancing means comprises a second coil holder means mounted opposite said first coil holder means for rotation about a third vertical axis.
Claim 4
Dependent Claim 21 words
A centrifuge as in claim 1, wherein the ratio of r to R is greater than 0.25 and less than 1.0.
Claim 5
Dependent Claim 24 words
A centrifuge as in claim 1, wherein the flexible core member is wound around the coil holder supporting surface in a substantially horizontal orientation.
Claim 6
Dependent Claim 24 words
A centrifuge as in claim 1, wherein the flexible core member is affixed to the coil holder supporting surface in a substantially vertical orientation.
Claim 7
Dependent Claim 26 words
A centrifuge as in claim 1, wherein the flexible core member is affixed to the coil holder supporting surface in an orientation between horizontal and vertical.
Claim 8
Dependent Claim 42 words
A centrifuge as in claim 1, wherein said drive means includes a motor in operative engagement with planetary gear means which are in operative engagement with solid coil holder means to thereby rotate said coil holder means and thereby said frame means.
Claim 9
Dependent Claim 29 words
A centrifuge as in claim 1, wherein said counterbalancing means comprises a counterweight mounted opposite said coil holder between said upper and lower plate members for free rotative movement.
Claim 10
Dependent Claim 17 words
A centrifuge as in claim 1, wherein the ratio of r to R is greater than 1.0.
Claim 11
Dependent Claim 195 words
A toroidal coil planet centrifuge, comprising: a support means provided with upper and lower stationary members; rotary frame means provided with upper and lower plate portions and mounted between said stationary members for rotation about a first vertical axis; at least one coil holder means mounted between said upper and lower plate members around a second vertical axis, said second vertical axis being spaced from said first vertical axis by distance R, and said coil holder means having a substantially cylinderical separation means supporting surface spaced from said second axis by distance r, the ratio of r to R being greater than 0.25; separation means mounted on said coil holder supporting surface, said separation means including at least one tube wrapped directly onto said cylinderical supporting surface and having two ends; inlet and outlet tubes connected to respective said ends of said at least one tube; a tube holding means located within said rotary frame means for holding said inlet and outlet tubes so that the orientation thereof will remain constant; drive means for rotating said frame means and coil holder means; and counterbalancing means mounted on said frame means opposite said coil holder means.
Claim 12
Dependent Claim 195 words
A toroidal coil planet centrifuge, comprising: a support means provided with upper and lower stationary members; rotary frame means provided with upper and lower plate portions and mounted between said stationary members for rotation about a first vertical axis; at least one coil holder means mounted between said upper and lower plate members around a second vertical axis, said second vertical axis being spaced from said first vertical axis by distance R, and said coil holder means having a substantially cylinderical separation means supporting surface spaced from said second axis by distance r, the ratio of r to R being greater than 0.25; separation means mounted on said coil holder supporting surface, said separation means including at least one tube wrapped directly onto said cylinderical supporting surface and having two ends; inlet and outlet tubes connected to respective said ends of said at least one tube; a tube holding means located within said rotary frame means for holding said inlet and outlet tubes so that the orientation thereof will remain constant; drive means for rotating said frame means and coil holder means; and counterbalancing means mounted on said frame means opposite said coil holder means.
Claim 13
Dependent Claim 21 words
A centrifuge as in claim 10, wherein the ratio of r to R is greater than 0.25 and less than 1.0
Claim 14
Dependent Claim 17 words
A centrifuge as in claim 10, wherein the ration of r to R is greater than 1.0.

References Cited (Backward Citations)

US3775309A Cited
US3994805A Cited
US4051025A Cited
US4058460A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1983-10-14 1984-04-14 1984-10-14 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1987-10-14 1988-04-14 1988-10-14 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1991-10-14 1992-04-14 1992-10-14 $7700.00 Window Closed / Lapsed

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