US4255414A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Edible or oral compositions
Assignee: Ferrero GmbH
•
Filing: 1979-01-24
•
Granted: 1981-03-10
•
Expires: 1999-01-24
Abstract
Abstract Edible or oral compositions which limit the promotion of tooth decay and comprise lactate dehydrogenase and sucrose-inverting enzymes. Included among such compositions are foods containing 0.1 to 2% water and either sugar or sugar substitutes. Foods without sugars and pharmaceutical preparations are also included in the scope of this invention.
Inventors
- 👤 Andreas Lembke
- 👤 Dietrich Gorny
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 15:05
CPC Classifications
A; A23; A23G; A23G3/00; A23G3/34; A23G3/36; A23G3/364; A23G3/366; A23G3/368; A23K; A23K20/00; A23K20/10; A23K20/189; A23L; A23L29/00; A23L29/06; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/64; A61K8/66; A61P; A61P1/00; A61P1/02; A61Q; A61Q11/00
Claims Analysis
Total Claims: 49
Claim 1
Independent Claim
35 words
An edible or oral low moisture content composition which composition contains sugar, sugar substitutes or no sugar and a content of the enzymes lactate dehydrogenase and sucrose-inverting enzyme sufficient to limit promotion of tooth decay.
Claim 2
Dependent Claim
35 words
An edible or oral low moisture content composition which composition contains sugar, sugar substitutes or no sugar and a content of the enzymes lactate dehydrogenase and sucrose-inverting enzyme sufficient to limit promotion of tooth decay.
Claim 3
Dependent Claim
9 words
A compositon according to claim 1 which contains sucrose.
Claim 4
Dependent Claim
39 words
A composition according to either of claims 1 or 2 in which the content of the enzymes lactate dehydrogenase and sucrose-inverting enzyme is at least sufficient to prevent the formation of cariogenic decomposition products or of products promoting caries.
Claim 5
Dependent Claim
25 words
A composition according to claims 1 or 2 which further contains a suitable hydrogen acceptor to intensify the effects of the content of lactate dehydrogenase.
Claim 6
Dependent Claim
18 words
A composition according to any one of claims 1 or 2 wherein the enzyme is β-fructosidase or α-glucosidase.
Claim 7
Dependent Claim
15 words
A composition according to any one of claims 1 or 2 which is a food.
Claim 8
Dependent Claim
21 words
A composition according to any one of claims 1 or 2 which is a pharmaceutical composition for tooth or mouth care.
Claim 9
Independent Claim
52 words
A method for the production of an edible or oral low moisture content composition which contains sugar, sugar substitutes or no sugar and which comprises adding lactate dehydrogenase and sucrose-inverting enzyme to the composition during or after the production of the composition in an amount sufficient to limit promotion of tooth decay.
Claim 10
Independent Claim
52 words
A method for the production of an edible or oral low moisture content composition which contains sugar, sugar substitutes or no sugar and which comprises adding lactate dehydrogenase and sucrose-inverting enzyme to the composition during or after the production of the composition in an amount sufficient to limit promotion of tooth decay.
Claim 11
Dependent Claim
19 words
A method according to claim 8 wherein the enzymes are introduced into the composition to achieve a homogeneous distribution.
Claim 12
Independent Claim
34 words
A method according to either of claims 8 or 9 wherein the composition is kept at pH-values for enzyme stability or under conditions of optimal enzyme stability during the time the enzymes are added.
Claim 13
Dependent Claim
26 words
A method according to claim 10 wherein the composition is kept at a pH of from 4 and 7 during the time the enzymes are added.
Claim 14
Dependent Claim
14 words
A method according to claim 12 wherein the pH is from 4.7 to 5.2.
Claim 15
Independent Claim
33 words
A method according to any one of claims 8 or 9 wherein the composition is kept at a temperature of from 20 to 50 degrees Centigrade during the time the enzymes are added.
Claim 16
Independent Claim
19 words
A method according to any one of claims 8 or 9 wherein the sucrose-inverting enzyme is β-fructosidase or α-glucosidase.
Claim 17
Dependent Claim
21 words
A method according to claim 10 wherein a suitable hydrogen acceptor is added to intensify the effects of the lactate dehydrogenase.
Claim 18
Dependent Claim
19 words
An edible or oral composition when produced by a method according to any one of claims 8 or 12.
Claim 19
Dependent Claim
23 words
A composition according to claim 3 which further contains a suitable hydrogen acceptor to intensify the effects of the content of lactate dehydrogenase.
Claim 20
Dependent Claim
13 words
A composition according to claim 3 wherein the enzyme is β-fructosidase or α-glucosidase.
Claim 21
Dependent Claim
13 words
A composition according to claim 4 wherein the enzyme is β-fructosidase or α-glucosidase.
Claim 22
Dependent Claim
10 words
A composition according to claim 3 which is a food.
Claim 23
Dependent Claim
10 words
A composition according to claim 4 which is a food.
Claim 24
Dependent Claim
10 words
A composition according to claim 5 which is a food.
Claim 25
Dependent Claim
16 words
A composition according to claim 3 which is a pharmaceutical composition for tooth or mouth care.
Claim 26
Dependent Claim
16 words
A composition according to claim 4 which is a pharmaceutical composition for tooth or mouth care.
Claim 27
Dependent Claim
16 words
A composition according to claim 5 which is a pharmaceutical composition for tooth or mouth care.
Claim 28
Dependent Claim
25 words
A method according to claim 10 wherein the composition is kept at a temperature of from 20°-50° C. during the time the enzymes are added.
Claim 29
Dependent Claim
25 words
A method according to claim 11 wherein the composition is kept at a temperature of from 20°-50° C. during the time the enzymes are added.
Claim 30
Dependent Claim
25 words
A method according to claim 12 wherein the composition is kept at a temperature of from 20°-50° C. during the time the enzymes are added.
Claim 31
Dependent Claim
14 words
A method according to claim 10 wherein the sucrose-inverting enzyme is β-fructosidase or α-glucosidase.
Claim 32
Dependent Claim
14 words
A method according to claim 11 wherein the sucrose-inverting enzyme is β-fructosidase or α-glucosidase.
Claim 33
Dependent Claim
14 words
A method according to claim 12 wherein the sucrose-inverting enzyme is β-fructosidase or α-glucosidase.
Claim 34
Dependent Claim
14 words
A method according to claim 13 wherein the sucrose-inverting enzyme is β-fructosidase or α-glucosidase.
Claim 35
Dependent Claim
21 words
A method according to claim 10 wherein a suitable hydrogen acceptor is added to intensify the effects of the lactate dehydrogenase.
Claim 36
Dependent Claim
21 words
A method according to claim 11 wherein a suitable hydrogen acceptor is added to intensify the effects of the lactate dehydrogenase.
Claim 37
Dependent Claim
13 words
An edible or oral composition produced by a method according to claim 10.
Claim 38
Dependent Claim
13 words
An edible or oral composition produced by a method according to claim 11.
Claim 39
Dependent Claim
13 words
An edible or oral composition produced by a method according to claim 13.
Claim 40
Dependent Claim
13 words
An edible or oral composition produced by a method according to claim 14.
Claim 41
Dependent Claim
13 words
An edible or oral composition produced by a method according to claim 15.
Claim 42
Dependent Claim
13 words
An edible or oral composition produced by a method according to claim 8.
Claim 43
Dependent Claim
96 words
An edible or oral low moisture content composition which contains sugar, sugar substitute or no sugar and a content of the enzymes lactate dehydrogenase and sucrose-inverting enzyme which limits the promotion of tooth decay and wherein the lactate dehydrogenase is present in a range of from about 0.2 mg to about 0.5 g per kg relative to a specific activity of about 300 U/mg of composition and wherein the sucrose-inverting enzyme is present in an amount from about 0.05 g to 5.0 g per kg of composition relative to a specific activity of about 100 U/mg.
Claim 44
Dependent Claim
96 words
An edible or oral low moisture content composition which contains sugar, sugar substitute or no sugar and a content of the enzymes lactate dehydrogenase and sucrose-inverting enzyme which limits the promotion of tooth decay and wherein the lactate dehydrogenase is present in a range of from about 0.2 mg to about 0.5 g per kg relative to a specific activity of about 300 U/mg of composition and wherein the sucrose-inverting enzyme is present in an amount from about 0.05 g to 5.0 g per kg of composition relative to a specific activity of about 100 U/mg.
Claim 45
Dependent Claim
33 words
A composition according to claim 41 wherein the lactate dehydrogenase is present in an amount from about 0.5 mg-0.05 g per kg of composition relative to a specific activity of about 300 U/mg.
Claim 46
Dependent Claim
15 words
A composition according to claim 1 which further contains nicotin-amide-adenine dinucleotide as a hydrogen acceptor.
Claim 47
Dependent Claim
29 words
An edible low moisture content composition which composition contains sugar and a content of the enzyme lactate dehydrogenase and sucrose-inverting enzyme sufficient to limit the promotion of tooth decay.
Claim 48
Dependent Claim
29 words
An edible low moisture content composition which composition contains sugar and a content of the enzyme lactate dehydrogenase and sucrose-inverting enzyme sufficient to limit the promotion of tooth decay.
Claim 49
Dependent Claim
29 words
A composition according to claim 1 which is a tooth-cleansing dragee comprising magnesium carbonate, silicon, dioxide, dicalcium phosphate, a urea-formaldehyde condensate, a long-chain amine fluoride, lactate dehydrogenase, and β-h-fructosidase.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-03-09 | 1984-09-08 | 1985-03-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-03-09 | 1988-09-08 | 1989-03-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-03-09 | 1992-09-08 | 1993-03-10 | $7700.00 | Window Closed / Lapsed |