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US4270923A Expired / Lapsed US ⏱️ 0.0 years remaining

Pretreatment agent for subject fluid in pregnancy test

Assignee: Takeda Pharmaceutical Co Ltd
•
Filing: 1979-12-26
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Granted: 1981-06-02
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Expires: 1999-12-26
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Abstract

Abstract By using a new pretreatment agent consisting essentially of a carboxylic acid-type cation exchange resin fiber or a siliconized glass fiber, the interfering components and the elements of turbidity present in a subject fluid for immunologic pregnancy test can be specifically removed without entailing a substantial loss of human chorionic gonadotropin contained in the subject fluid.

Inventors

  • 👤 Koichi Kondo
  • 👤 Isamu Yoshida
  • 👤 Takashi Kobayashi

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-07 01:30
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/74; G01N33/76; Y; Y10; Y10S; Y10S436/00; Y10S436/811; Y10S436/814; Y10S436/815; Y10S436/817; Y10S436/818; Y10S436/825

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 77 words
A method for pretreating a subject fluid for a pregnancy test by means of an immunologic assay of human chorionic gonadotropin, which comprises removing the interfering components and turbidity from the subject fluid by contacting the subject fluid with a carboxylic acid-type cation exchange resin fiber having a cation exchange capacity of about 5 to 8 meq/g or a siliconized glass fiber prepared by impregnating a glass fiber with a solution of dimethylpolysiloxane and heating the fiber.
Claim 2
Independent Claim 77 words
A method for pretreating a subject fluid for a pregnancy test by means of an immunologic assay of human chorionic gonadotropin, which comprises removing the interfering components and turbidity from the subject fluid by contacting the subject fluid with a carboxylic acid-type cation exchange resin fiber having a cation exchange capacity of about 5 to 8 meq/g or a siliconized glass fiber prepared by impregnating a glass fiber with a solution of dimethylpolysiloxane and heating the fiber.
Claim 3
Dependent Claim 15 words
A method according to claim 1, wherein the subject fluid is woman's urine or serum.
Claim 4
Dependent Claim 28 words
A method according to claim 1, wherein the subject fluid is filtered through a layer of the carboxylic acid-type cation exchange resin fiber or the siliconized glass fiber.
Claim 5
Dependent Claim 28 words
A method according to claim 3, wherein the resin fiber is in the form of filament or staple fiber with a denier number of about 2 to 15.
Claim 6
Dependent Claim 29 words
A method according to claim 3, wherein the layer is of the siliconized glass fiber in the form of filament with a diameter of about 5 to 15 μm.
Claim 7
Dependent Claim 26 words
A method according to claim 3, wherein the amount of the fibrous layer is about 20 to 100 mg per 0.3 ml of the subject fluid.

References Cited (Backward Citations)

US3215500A Cited
US3171783A Cited
US3594993A Cited
US3873682A Cited
US3901657A Cited
US4160644A Cited
US4138214A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1984-06-01 1984-12-01 1985-06-02 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1988-06-01 1988-12-01 1989-06-02 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1992-06-01 1992-12-01 1993-06-02 $7700.00 Window Closed / Lapsed

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