US4292199A
Expired / Lapsed
US
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Method of preparing a support matrix
Assignee: Honeywell UOP LLC
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Filing: 1980-08-18
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Granted: 1981-09-29
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Expires: 2000-08-18
Abstract
Abstract An improved method of preparing support matrices, characterized as inorganic oxides impregnated with a polyamine cross-linked with a bifunctional reagent so as to furnish a plurality of pendant functional groups, comprises impregnating the oxide at a pH less than about 4 and subsequently curing the polyamine-impregnated oxide at a pH from about 8 to about 12. This improved method leads to subsequently prepared immobilized enzyme systems whose activity is increased by about 35%.
Inventors
- 👤 Ronald P. Rohrbach
- 👤 Mary J. Maliarik
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 18:15
CPC Classifications
B; B01; B01J; B01J31/00; B01J31/02; B01J31/0234; B01J31/0235; B01J31/0254; B01J31/003; B01J31/06; C; C12; C12N; C12N11/00; C12N11/02; C12N11/08; C12N11/089; C12N11/14
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
84 words
In a method of preparing a support matrix including impregnating a porous, refractory inorganic oxide with a polyamine, contacting the impregnated oxide with an excess of a bifunctional reagent so as to cross-link the polyamine and furnish a plurality of pendant functional groups, removing unreacted but adhering bifunctional reagent, and recovering the suport matrix, the improvement comprising: impregnating the oxide with a polyamine at a pH less than about 4 and thereafter curing the impregnated oxide at a pH from about 8 to 12.
Claim 2
Dependent Claim
84 words
In a method of preparing a support matrix including impregnating a porous, refractory inorganic oxide with a polyamine, contacting the impregnated oxide with an excess of a bifunctional reagent so as to cross-link the polyamine and furnish a plurality of pendant functional groups, removing unreacted but adhering bifunctional reagent, and recovering the suport matrix, the improvement comprising: impregnating the oxide with a polyamine at a pH less than about 4 and thereafter curing the impregnated oxide at a pH from about 8 to 12.
Claim 3
Dependent Claim
22 words
The method of claim 1 wherein the oxide is impregnated with a polyamine at a pH from about 1 to about 3.
Claim 4
Dependent Claim
20 words
The method of claim 1 wherein the impregnated oxide is cured at a pH from about 9 to about 11.
Claim 5
Dependent Claim
23 words
The method of claim 1 wherein the inorganic oxide is selected from the group consisting of alumina, thoria, magnesia, slica, and combinations thereof.
Claim 6
Dependent Claim
10 words
The method of claim 4 wherein the oxide is alumina.
Claim 7
Dependent Claim
24 words
The method of claim 1 wherein the polyamine is selected from the group consisting of polyethyleneimine, tetraethylenepentamine, ethylenediamine, diethylenetriamine, triethylenetetramine, pentaethylenehexamine, hexamethylenediamine, and phenylenediamine.
Claim 8
Dependent Claim
10 words
The method of claim 6 wherein the polymaine is polyethyleneimine.
Claim 9
Dependent Claim
21 words
The method of claim 1 wherein the bifunctional reagent is selected from the group consisting of glutaraldehyde, succindialdehyde, terephthaldehyde, and toluenediisocyanate.
Claim 10
Dependent Claim
11 words
The method of claim 1 wherein the bifunctional reagent is glutaraldehyde.
References Cited (Backward Citations)
US4141857A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-09-28 | 1985-03-30 | 1985-09-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-09-28 | 1989-03-30 | 1989-09-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-09-28 | 1993-03-30 | 1993-09-29 | $7700.00 | Window Closed / Lapsed |