US4309442A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method for controlling fertility in mammals
Assignee: Merrell Toraude et Cie
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Filing: 1980-12-03
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Granted: 1982-01-05
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Expires: 2000-12-03
Abstract
Abstract A method for preventing gestation in mammals comprising the administration of a 2,5-diamino-2-halomethylpentanoic acid or derivative thereof.
Inventors
- 👤 Philippe Bey
- 👤 Michel Jung
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 11:17
CPC Classifications
C; C07; C07H; C07H19/00; C07H19/02; C07H19/04; C07H19/16; A; A61; A61K; A61K31/00; A61K31/16; A61K31/185; A61K31/19; A61K31/195; C07D; C07D211/00; C07D211/04; C07D211/68; C07D211/72; C07D211/74; C07D211/76; C07D223/00; C07D223/02; C07D223/06; C07D223/08; C07K; C07K5/00; C07K5/04; C07K5/06; C07K5/06191; A61K38/00
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
130 words
A method of preventing gestation in mammals which comprises the administration to said mammals of a contragestationally effective amount of a compound of the formula: ##STR14## wherein: Y is FCH 2 --, F 2 CH--, or F 3 C--; R a and R b are, independently, hydrogen, (C 1 -C 4 )alkylcarbonyl, or the group ##STR15## wherein R 2 is hydrogen, (C 1 -C 4 ) alkyl, benzyl, or p-hydroxybenyl; R 1 is hydroxy, (C 1 -C 8 ) alkoxy, the group --NR 4 R 5 , wherein R 4 and R 5 are, independently, hydrogen, or, (C 1 -C 4 )alkyl, or the group ##STR16## wherein R 3 is hydrogen, (C 1 -C 4 ) alkyl, benzyl, or p-hydroxybenzyl; and the pharmaceutically acceptable salts and individual optical isomers thereof.
Claim 2
Independent Claim
130 words
A method of preventing gestation in mammals which comprises the administration to said mammals of a contragestationally effective amount of a compound of the formula: ##STR14## wherein: Y is FCH 2 --, F 2 CH--, or F 3 C--; R a and R b are, independently, hydrogen, (C 1 -C 4 )alkylcarbonyl, or the group ##STR15## wherein R 2 is hydrogen, (C 1 -C 4 ) alkyl, benzyl, or p-hydroxybenyl; R 1 is hydroxy, (C 1 -C 8 ) alkoxy, the group --NR 4 R 5 , wherein R 4 and R 5 are, independently, hydrogen, or, (C 1 -C 4 )alkyl, or the group ##STR16## wherein R 3 is hydrogen, (C 1 -C 4 ) alkyl, benzyl, or p-hydroxybenzyl; and the pharmaceutically acceptable salts and individual optical isomers thereof.
Claim 3
Dependent Claim
17 words
A method as defined in claim 1 wherein Y is --CH 2 F or --CHF 2 .
Claim 4
Dependent Claim
14 words
A method as defined in claim 1 or 2 wherein R 1 is hydroxy.
Claim 5
Dependent Claim
19 words
A method as defined in claim 1 or 2 wherein R 1 is hydroxy and R a is hydrogen.
Claim 6
Dependent Claim
19 words
A method as defined in claim 1 or 2 wherein R 1 is hydroxy and R b is hydrogen.
Claim 7
Dependent Claim
17 words
A method as defined in claim 1 or 2 wherein R a and R b are hydrogen.
Claim 8
Dependent Claim
14 words
A method as defined in claim 2 which comprises the administration of 2,5-diamino-2-fluoromethylpentanoic acid.
Claim 9
Dependent Claim
14 words
A method as defined in claim 2 which comprises the administration of 2,5-diamino-2-diamino-2-difluoromethylpentanoic acid.
References Cited (Backward Citations)
US2662915A
Cited
US3168558A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-01-04 | 1985-07-06 | 1986-01-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-01-04 | 1989-07-06 | 1990-01-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-01-04 | 1993-07-06 | 1994-01-05 | $7700.00 | Window Closed / Lapsed |