Disulfide compounds

Claim 1

A compound of the formula ##STR40## wherein Q is sulfur; R a is R 1 , R 7 , or R 10 ; R b is R 2 , R 8 , or R 11 ; R c is R 3 , R 9 , or R 12 ; and when R a is R 1 , R b is R 2 , and R c is R 3 ; or R a is R 7 , R b is R 8 , and R c is R 9 ; or R a is R 10 , R b is R 11 , and R c is R 12 A is alkylene having 1 to 3 carbon atoms; R 1 is lower alkanoylmercapto-lower alkyl, benzoylmercapto-lower alkyl, alkyl having 8 to 20 carbon atoms, alkenyl having 2 to 20 carbon atoms, cycloalkyl, phenyl, furyl, thienyl, pyridyl, naphthyl, substituted cycloalkyl, substituted aralkyl, substituted phenyl, substituted furyl, substituted thienyl, substituted pyridyl or substituted napththyl wherein the substituents are 1 to 3 groups independently selected from lower alkyl, hydroxy, lower alkoxy, lower alkylenedioxy, lower alkanoyloxy, benzoyloxy, benzyloxycarbonyloxy, lower alkanoylmercapto, benzoylmercapto, halogen, nitro, amino, lower alkylamino, lower alkanoylamino, benzoylamino, benzyloxycarbonylamino, carboxy, sulfamoyl and lower alkylaminosulfonyl; R 2 is hydroxy, lower alkoxy, amino, phenoxy, substituted lower alkoxy wherein the substituent is hydroxy, succinimido, maleimido, phthalimido or lower alkanoyloxy or substituted phenoxy wherein the substituent is hydroxy, lower alkoxy or halogen; R 3 is alkyl having 1 to 10 carbon atoms, phenyl, lower alkenyl, phenylloweralkyl, tetrahydrofuryl-lower alkyl, R 19 , ##STR41## substituted lower alkyl or substituted phenyl wherein the substituents are 1 to 2 groups independently selected from lower alkyl, hydroxy, lower alkoxy, lower alkanoyloxy, benzoyloxy, benzyloxycarbonyloxy, amino, lower alkylamino, lower alkanoylamino, benzoylamino, benzyloxycarbonylamino, carboxy and carbamoyl; R 7 and R 10 each is hydrogen or lower alkyl; R 8 is hydroxy or lower alkoxy; R 9 is alkyl having 1 to 10 carbon atoms, lower alkenyl, tetrahydrofuryl-lower alkyl, phenyl, aralkyl, R 19 , substituted lower alkyl or substituted phenyl wherein the substituents are 1 to 2 groups independently selected from lower alkyl, hydroxy, lower alkoxy, lower alkanoyloxy, benzoyloxy, benzyloxycarbonyloxy, amino, lower alkylamino, lower alkanoylamino, benzoylamino, benzyloxycarbonylamino, carboxy and carbamoyl; R 11 is amino, phenoxy or substituted lower alkoxy wherein the substituent is hydroxy, succinimido, maleimido, phthalimido or lower alkanoyloxy; R 12 is alkyl having 1 to 10 carbon atoms, lower alkenyl, tetrahydrofuryl-lower alkyl or ##STR42## R 19 is ##STR43## B is lower alkylene; R 20 and R 22 each is hydrogen or lower alkyl; R 21 is hydrogen, lower alkyl lower alkanoylmercapto-lower alkyl, or benzoylmercapto-lower alkyl; wherein the terms lower alkyl, lower alkoxy, lower alkenyl, lower alkylene, and lower alkanoyl refer to groups containing from 1 to 7 carbon atoms, and the cycloalkyl groups are cyclohexyl groups.