US4353822A
Expired / Lapsed
US
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Antigenic linear peptide compounds
Assignee: Northwestern University
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Filing: 1981-05-26
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Granted: 1982-10-12
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Expires: 2001-05-26
Abstract
Abstract The novel antigenic linear peptide compounds of this invention are characterized by providing a sequence of eight amino acids comprising isoleucine-serine-glycine-phenylalanine-proline-valine-glycine-arginine, all of the amino acids with the exception of glycine being in their L-forms. The isoleucine may comprise the N-terminal end or may be bonded to N-terminal glycine, and the arginine may be the C-terminal amino acid or may be bonded to C-terminal valine. The compounds have utility in vaccines for reducing the fertility of mammals.
Inventors
- 👤 Erwin Goldberg
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 10:17
CPC Classifications
C; C07; C07K; C07K7/00; C07K7/04; C07K7/06; A; A61; A61K; A61K39/00; A61K39/0005; A61K39/0006; C12; C12N; C12N9/00; C12N9/0004; C12N9/0006
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
76 words
The linear peptide compounds having chain lengths of from 8 to 10 amino acids arranged in a sequence from N-terminal to C-terminal amino acids which include the antigenic sequence Ile-Ser-Gly-Phe-Pro-Val-Gly-Arg, said compounds being selected from the class of compounds consisting of: (a) Ile-Ser-Gly-Phe-Pro-Val-Gly-Arg, (b) Ile-Ser-Gly-Phe-Pro-Val-Gly-Arg-Val, (c) Gly-Ile-Ser-Gly-Phe-Pro-Val-Gly-Arg, and (d) Gly-Ile-Ser-Gly-Phe-Pro-Val-Gly-Arg-Val, wherein Gly represents glycine, and Ile, Ser, Phe, Pro, Val, and Arg, respectively represent the L-amino acid forms of isoleucine, serine, phenylanine, proline, valine, and arginine.
Claim 2
Dependent Claim
76 words
The linear peptide compounds having chain lengths of from 8 to 10 amino acids arranged in a sequence from N-terminal to C-terminal amino acids which include the antigenic sequence Ile-Ser-Gly-Phe-Pro-Val-Gly-Arg, said compounds being selected from the class of compounds consisting of: (a) Ile-Ser-Gly-Phe-Pro-Val-Gly-Arg, (b) Ile-Ser-Gly-Phe-Pro-Val-Gly-Arg-Val, (c) Gly-Ile-Ser-Gly-Phe-Pro-Val-Gly-Arg, and (d) Gly-Ile-Ser-Gly-Phe-Pro-Val-Gly-Arg-Val, wherein Gly represents glycine, and Ile, Ser, Phe, Pro, Val, and Arg, respectively represent the L-amino acid forms of isoleucine, serine, phenylanine, proline, valine, and arginine.
Claim 3
Dependent Claim
12 words
The antigenic peptide of claim 1 having the amino acid sequence (a).
Claim 4
Dependent Claim
12 words
The antigenic peptide of claim 1 having the amino acid sequence (b).
Claim 5
Dependent Claim
12 words
The antigenic peptide of claim 1 having the amino acid sequence (c).
Claim 6
Dependent Claim
12 words
The antigenic peptide of claim 1 having the amino acid sequence (d).
References Cited (Backward Citations)
US4310456A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-10-11 | 1986-04-12 | 1986-10-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-10-11 | 1990-04-12 | 1990-10-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-10-11 | 1994-04-12 | 1994-10-12 | $7700.00 | Window Closed / Lapsed |