US4374765A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Mammalian collagenase inhibitors
Assignee: Wyeth LLC
•
Filing: 1981-10-07
•
Granted: 1983-02-22
•
Expires: 2001-10-07
Abstract
Abstract The polypeptides R-Gly-L-Cys-Gly-L-Glu-L-Glu-NH 2 or a pharmaceutically acceptable salt thereof act as collagenase inhibitors useful in the treatment of disease involving excessive tissue destruction by collagenase.
Inventors
- 👤 William H. McGregor
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 19:08
CPC Classifications
C; C07; C07K; C07K7/00; C07K7/04; C07K7/06; A; A61; A61K; A61K38/00
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
39 words
A compound of the formula: R-Gly-L-Cys-Gly-L-Glu-L-Glu-NH.sub.2 in which R is hydrogen, alkanoyl of 2 to 6 carbon atoms, cycloalkylcarbonyl of 6 to 8 carbon atoms or alkoxycarbonyl of 2 to 6 carbon atoms; or a pharmaceutically acceptable salt thereof.
Claim 2
Dependent Claim
39 words
A compound of the formula: R-Gly-L-Cys-Gly-L-Glu-L-Glu-NH.sub.2 in which R is hydrogen, alkanoyl of 2 to 6 carbon atoms, cycloalkylcarbonyl of 6 to 8 carbon atoms or alkoxycarbonyl of 2 to 6 carbon atoms; or a pharmaceutically acceptable salt thereof.
Claim 3
Dependent Claim
17 words
The compound of claim 1 which is CH 3 CO-Gly-L-Cys-Gly-L-Glu-L-Glu-NH 2 or a pharmaceutically acceptable salt thereof.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-02-21 | 1986-08-23 | 1987-02-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-02-21 | 1990-08-23 | 1991-02-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-02-21 | 1994-08-23 | 1995-02-22 | $7700.00 | Window Closed / Lapsed |