US4377516A
Expired / Lapsed
US
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Antigenic linear peptide compounds
Assignee: Northwestern University
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Filing: 1981-12-10
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Granted: 1983-03-22
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Expires: 2001-12-10
Abstract
Abstract The novel antigenic linear peptide compounds of this invention comprise sequences of from 10 to 14 amino acids which include the sequence arginine-methionine-valine-serine-glycine-glutamine-threonine-arginine-leucine-aspartic acid, all of the amino acids with the exception of glycine being in their L-forms. The compounds have utility in vaccines for reducing fertility of mammals.
Inventors
- 👤 Erwin Goldberg
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 22:57
CPC Classifications
C; C07; C07K; C07K7/00; C07K7/04; C07K7/06; A; A61; A61K; A61K39/00; A61K39/0005; A61K39/0006; C07K7/08; Y; Y10; Y10S; Y10S530/00; Y10S530/806
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
82 words
The antigenic peptide compounds having chain lengths of from 10 to 14 amino acids arranged in a sequence from N-terminal to C-terminal amino acids which include the antigenic sequence Arg-Met-Val-Ser-Gly-Gln-Thr-Arg-Leu-Asp, said compounds being selected from the class of compounds consisting of: (a) Arg-Met-Val-Ser-Gly-Gln-Thr-Arg-Leu-Asp, (b) Arg-Met-Val-Ser-Gly-Gln-Thr-Arg-Leu-Asp-Leu, (c) Arg-Met-Val-Ser-Gly-Gln-Thr-Arg-Leu-Asp-Leu-Leu, (d) Arg-Met-Val-Ser-Gly-Gln-Thr-Arg-Leu-Asp-Leu-Leu-Gln, and (e) Arg-Met-Val-Ser-Gly-Gln-Thr-Arg-Leu-Asp-Leu-Leu-Gln-Arg, wherein Gly represents glycine, and Arg, Met, Val, Ser, Gln, Thr, Leu, Asp, respectively represent the L-amino acid forms of arginine, methionine, valine, serine, glutamine, threonine, leucine, and aspartic acid.
Claim 2
Dependent Claim
82 words
The antigenic peptide compounds having chain lengths of from 10 to 14 amino acids arranged in a sequence from N-terminal to C-terminal amino acids which include the antigenic sequence Arg-Met-Val-Ser-Gly-Gln-Thr-Arg-Leu-Asp, said compounds being selected from the class of compounds consisting of: (a) Arg-Met-Val-Ser-Gly-Gln-Thr-Arg-Leu-Asp, (b) Arg-Met-Val-Ser-Gly-Gln-Thr-Arg-Leu-Asp-Leu, (c) Arg-Met-Val-Ser-Gly-Gln-Thr-Arg-Leu-Asp-Leu-Leu, (d) Arg-Met-Val-Ser-Gly-Gln-Thr-Arg-Leu-Asp-Leu-Leu-Gln, and (e) Arg-Met-Val-Ser-Gly-Gln-Thr-Arg-Leu-Asp-Leu-Leu-Gln-Arg, wherein Gly represents glycine, and Arg, Met, Val, Ser, Gln, Thr, Leu, Asp, respectively represent the L-amino acid forms of arginine, methionine, valine, serine, glutamine, threonine, leucine, and aspartic acid.
Claim 3
Dependent Claim
12 words
The antigenic peptide of claim 1 having the amino acid sequence (a).
Claim 4
Dependent Claim
12 words
The antigenic peptide of claim 1 having the amino acid sequence (b).
Claim 5
Dependent Claim
12 words
The antigenic peptide of claim 1 having the amino acid sequence (c).
Claim 6
Dependent Claim
12 words
The antigenic peptide of claim 1 having the amino acid sequence (d).
Claim 7
Dependent Claim
12 words
The antigenic peptide of claim 1 having the amino acid sequence (e).
References Cited (Backward Citations)
US4310456A
Cited
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