US4385019A — Production of a polymeric active composition

Claim 1

Independent Claim 142 words

A method of preparing a polymeric active composition which can be developed into a shaped structure, said structure comprising solid active material encradled in a porous, fiber-containing polymeric material with maximized exposure of the surfaces of the active material, said method comprising providing the components of said composition as a substantially dry formulation comprising a support-contributing polymer, a fibrillatable polymer, an active material and a major amount of removable pore-former, subjecting said formulation to shear stresses at an elevated temperature to convert the fibrillatable polymer to a fibrous form and to form an intimate mixture of fibers, support-contributing polymer, active material and a major amount of removable pore-former, and shaping the fibrillated composition, thereby providing a shaped polymeric active composition in which porosity can be effected by removal of the pore-former with the resultant pores being interconnecting and dispersed throughout the structure.

Claim 2

Independent Claim 142 words

A method of preparing a polymeric active composition which can be developed into a shaped structure, said structure comprising solid active material encradled in a porous, fiber-containing polymeric material with maximized exposure of the surfaces of the active material, said method comprising providing the components of said composition as a substantially dry formulation comprising a support-contributing polymer, a fibrillatable polymer, an active material and a major amount of removable pore-former, subjecting said formulation to shear stresses at an elevated temperature to convert the fibrillatable polymer to a fibrous form and to form an intimate mixture of fibers, support-contributing polymer, active material and a major amount of removable pore-former, and shaping the fibrillated composition, thereby providing a shaped polymeric active composition in which porosity can be effected by removal of the pore-former with the resultant pores being interconnecting and dispersed throughout the structure.

Claim 3

Dependent Claim 15 words

A method according to claim 1, characterized in that the pore-former is soluble in water.

Claim 4

Dependent Claim 24 words

A method according to claim 2, characterized in that the pore-former is present in an amount of about 70% to about 80% by volume.

Claim 5

Dependent Claim 19 words

A method according to claim 1, characterized in that the polymeric active composition is prepared in a particulate form.

Claim 6

Dependent Claim 32 words

A method according to claim 5, characterized in that the polymeric active composition is prepared as a shaped product in the form of a sheet, bar, film, cylinder, ring, sphere, or pellet.

Claim 7

Dependent Claim 45 words

A method according to claim 1, characterized in that the polymeric active composition is comprised, by weight, of about 50% to about 75% active material, about 0.5% to about 5% fibrillatable polymer, about 47% to about 10% removable pore-former and the balance essentially support-contributing polymer.

Claim 8

Dependent Claim 23 words

A method according to claim 2, characterized in that the pore-former is a polymer having a molecular weight of about 100,000 to 1,000,000.

Claim 9

Dependent Claim 22 words

A method according to claim 2, characterized in that the pore-former is a polyethylene oxide, a polypropylene oxide, or a combination thereof.

Claim 10

Dependent Claim 54 words

A method according to claim 1, characterized in that the support contributing polymer is at least one polymer selected from the group consisting of polyethylene, polypropylene, polybutylene, polyisobutylene, and co-polymers thereof with each other of with ethylacrylate and/or vinyl acetate; halogenated polyhydrocarbons and co-polymers thereof; polyamides, polysulfones; polyacetates; polycarbonates; polyesters; cellulose esters or silicones.

Claim 11

Dependent Claim 18 words

A method according to claim 1, characterized in that the support-contributing polymer is a substantially saturated thermoplastic polymer.

Claim 12

Dependent Claim 24 words

A method according to claim 1, characterized in that the poreformer wets or can be made to wet the surfaces of the active material.

Claim 13

Dependent Claim 31 words

A method according to claim 1, characterized in that the components of the formulation are intimately mixed at a temperature in the range of about 65° C. to about 100° C.

Claim 14

Dependent Claim 47 words

A method according to claim 1, characterized in that the fibrillatable polymer and active material are mixed together independently of the mixture of support-contributing polymer and pore-former, and then the mixture of fibrillatable polymer and active material is added to the mixture of support-contributing polymer and pore-former.

Claim 15

Independent Claim 170 words

A method of preparing a polymeric active composition which can be developed into a shaped structure, said structure comprising active material encradled in a porous, fiber-containing polymeric material with maximized exposure of the surfaces of the active material, said method comprising providing the components of said composition as a substantially dry formulation comprised, by weight, of about 50% to about 75% solid active material, about 0.5% to about 5% fibrillatable polymer, 47% to about 10% removable pore-former and the balance essentially support-contributing polymer, said removable pore-former being a water-soluble polymer and being capable of wetting the active material, subjecting said formulation to shear stresses to convert the fibrillatable polymer to a fibrous form, forming the components at an elevated temperature into an intimate mixture of fibers, support-contributing polymer, active material and pore-former, and shaping the fibrillated composition, thereby providing a shaped polymeric active composition in which porosity can be effected by leaching the pore-former from the shaped structure with water, with resultant pores being interconnecting and dispersed throughout the material.

Claim 16

Independent Claim 170 words

A method of preparing a polymeric active composition which can be developed into a shaped structure, said structure comprising active material encradled in a porous, fiber-containing polymeric material with maximized exposure of the surfaces of the active material, said method comprising providing the components of said composition as a substantially dry formulation comprised, by weight, of about 50% to about 75% solid active material, about 0.5% to about 5% fibrillatable polymer, 47% to about 10% removable pore-former and the balance essentially support-contributing polymer, said removable pore-former being a water-soluble polymer and being capable of wetting the active material, subjecting said formulation to shear stresses to convert the fibrillatable polymer to a fibrous form, forming the components at an elevated temperature into an intimate mixture of fibers, support-contributing polymer, active material and pore-former, and shaping the fibrillated composition, thereby providing a shaped polymeric active composition in which porosity can be effected by leaching the pore-former from the shaped structure with water, with resultant pores being interconnecting and dispersed throughout the material.

Claim 17

Dependent Claim 21 words

A method according to claim 14, wherein the pore-former is removed from the shaped polymeric active composition by leaching with water.

Claim 18

Independent Claim 151 words

A method of preparing a polymeric active composition which can be developed into a shaped structure, said structure comprising active material encradled in a porous, fiber-containing polymeric material with maximized exposure of the surfaces of the active material, said method comprising providing the components of said composition as a substantially dry formulation comprising a support-contributing polymer, a fibrillatable polymer, a solid active material and a major amount of removable pore-former, said pore-former being solubilizable in an aqueous agent, subjecting said formulation to shear stresses to convert the fibrillatable polymer to a fibrous form, forming the components into an intimate mixture of fibers, support-contributing polymer active material and a major amount of removable pore-former, and shaping the fibrillated composition, thereby providing a shaped polymeric active composition in which porosity can be effected by removal of the pore-former with an aqueous agent, with the resultant pores being interconnecting and dispersed throughout the structure.

Claim 19

Independent Claim 151 words

A method of preparing a polymeric active composition which can be developed into a shaped structure, said structure comprising active material encradled in a porous, fiber-containing polymeric material with maximized exposure of the surfaces of the active material, said method comprising providing the components of said composition as a substantially dry formulation comprising a support-contributing polymer, a fibrillatable polymer, a solid active material and a major amount of removable pore-former, said pore-former being solubilizable in an aqueous agent, subjecting said formulation to shear stresses to convert the fibrillatable polymer to a fibrous form, forming the components into an intimate mixture of fibers, support-contributing polymer active material and a major amount of removable pore-former, and shaping the fibrillated composition, thereby providing a shaped polymeric active composition in which porosity can be effected by removal of the pore-former with an aqueous agent, with the resultant pores being interconnecting and dispersed throughout the structure.

Annuity Stage	Window Opens	Payment Deadline	Surcharge Period Until	Estimated Fee	Status
3.5 Years (Year 4)	1986-05-23	1986-11-22	1987-05-24	$2000.00	Window Closed / Lapsed
7.5 Years (Year 8)	1990-05-23	1990-11-22	1991-05-24	$3760.00	Window Closed / Lapsed
11.5 Years (Year 12)	1994-05-23	1994-11-22	1995-05-24	$7700.00	Window Closed / Lapsed

Production of a polymeric active composition

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