Patent JPS5368970A successfully refreshed from Google Patents.
US4386053A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Test piece for detection of occult blood
Assignee: THERMO Corp
•
Filing: 1981-08-31
•
Granted: 1983-05-31
•
Expires: 2001-08-31
Abstract
Abstract In a test piece for the detection of occult blood, obtained by impregnating a substrate with an organic peroxide, a chromogen, a buffer, and a stabilizer, at least one compound selected from the group of compounds represented by the general formula I: ##STR1## wherein, m denotes an integer of the value of 1 to 5, R 1 denotes one member selected from the group consisting of methyl group, lower alkoxy group, halogen atoms, and hydrogen atom, and X denotes one group selected from the group consisting of ##STR2## where, R 2 and R 3 each denote an alkyl group having 1 or 2 carbon atoms, ##STR3## where, m, R 1 , R 2 , and R 3 are as defined above, R 4 denotes an alkylene group having 1 to 6 carbon atoms, and n is 0 or 1, ##STR4## where, m, R 1 , R 4 are as defined above, and ##STR5## where, R 2 and R 3 are as defined above.
Inventors
- 👤 Hiroshi Motobayashi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 13:08
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/72; G01N33/721; G01N33/725; C; C12; C12Q; C12Q1/00; C12Q1/26; C12Q1/28; Y; Y10; Y10S; Y10S436/00; Y10S436/904
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
167 words
In a test piece for the detection of occult blood or another peroxidatively active substance in body fluids including a substrate impregnated with an organic hydroperoxide, a chromogen, a buffer, and a stabilizer, the improvement wherein said stabilizer comprises at least one compound of the general formula I: ##STR24## wherein, m denotes an integer of 1 to 5, R 1 denotes one member selected from the group consisting of methyl group, lower alkoxy group, halogen atoms and hydrogen atom, and X denotes one member selected from the group consisting of ##STR25## where, R 2 and R 3 each denote an alkyl group having 1 or 2 carbon atoms, ##STR26## where, m, R 1 , R 2 , and R 3 are as defined above, R 4 denotes an alkylene group having 1 to 6 carbon atoms, and n is 0 or 1, ##STR27## wherein, m, R 1 , and R 4 are as defined above, and ##STR28## where, R 2 and R 3 are as defined above.
Claim 2
Dependent Claim
167 words
In a test piece for the detection of occult blood or another peroxidatively active substance in body fluids including a substrate impregnated with an organic hydroperoxide, a chromogen, a buffer, and a stabilizer, the improvement wherein said stabilizer comprises at least one compound of the general formula I: ##STR24## wherein, m denotes an integer of 1 to 5, R 1 denotes one member selected from the group consisting of methyl group, lower alkoxy group, halogen atoms and hydrogen atom, and X denotes one member selected from the group consisting of ##STR25## where, R 2 and R 3 each denote an alkyl group having 1 or 2 carbon atoms, ##STR26## where, m, R 1 , R 2 , and R 3 are as defined above, R 4 denotes an alkylene group having 1 to 6 carbon atoms, and n is 0 or 1, ##STR27## wherein, m, R 1 , and R 4 are as defined above, and ##STR28## where, R 2 and R 3 are as defined above.
Claim 3
Dependent Claim
52 words
A test piece according to claim 1, wherein m denotes 1, R 1 denotes one member selected from the group consisting of methyl group, methoxy group, bromine atom, chlorine atom and hydrogen atom, and R 4 denotes an alkylene group having 2 to 6 carbon atoms respectively in the general formula I.
Claim 4
Dependent Claim
26 words
A test piece according to claim 1, wherein X denotes ##STR29## where, R 2 and R 3 are as defined above in the general formula I.
Claim 5
Dependent Claim
33 words
A test piece according to claim 1, wherein X denotes ##STR30## where, m, R 1 , R 2 , R 3 and R 4 are as defined above in the general formula I.
Claim 6
Dependent Claim
28 words
A test piece according to claim 1, wherein X denotes ##STR31## where, m, R 1 , and R 4 are as defined above in the general formula I.
Claim 7
Dependent Claim
26 words
A test piece according to claim 1, wherein X denotes ##STR32## where, R 2 and R 3 are as defined above in the general formula I.
Claim 8
Dependent Claim
18 words
A test piece according to claim 1, which further comprises a wetting agent and a peroxidase activity enhancer.
Claim 9
Dependent Claim
12 words
A test piece according to claim 7, which further comprises a tackifier.
Claim 10
Dependent Claim
28 words
A test piece according to claim 2, wherein the stabilizer is a compound selected from the group consisting of p-bromobenzoyl dimethylamide, N,N'-dibenzoyl-N,N'-diethylethylene diamine, p-toluene sulfonyl-N-diethylamide, and N,N'-ditoluoyl-N,N'-diethylene diamine.
Claim 11
Dependent Claim
27 words
A test piece according to claim 9, wherein the organic hydroperoxide is at least one compound selected from the group consisting of 2,5-dimethylhexane-2,5-dihydroperoxide, cumene hydroperoxide, and 2,5-dimethylhexanone-2,5-dihydroperoxide.
Claim 12
Dependent Claim
13 words
A test piece according to claim 10, wherein the organic hydroperoxide is 2,5-dimethylhexane-2,5-dihydroperoxide.
Claim 13
Dependent Claim
19 words
A test piece according to any one of claims 9, 10 or 11, wherein said stabilizer is p-bromobenzoyl dimethylamide.
Claim 14
Dependent Claim
19 words
A test piece according to any one of claims 9, 10 or 11, wherein said stabilizer is N,N'-dibenzoyl-N,N'-diethylethylene diamine.
Claim 15
Dependent Claim
19 words
A test piece according to any one of claims 9, 10 or 11, wherein said stabilizer is p-toluene sulfonyl-N-diethylamide.
Claim 16
Dependent Claim
19 words
A test piece according to any one of claims 9, 10 or 11, wherein said stabilizer is N,N'-ditoluoyl-N,N'-diethylene diamine.
References Cited (Backward Citations)
US4290773A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-05-30 | 1986-11-29 | 1987-05-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-05-30 | 1990-11-29 | 1991-05-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-05-30 | 1994-11-29 | 1995-05-31 | $7700.00 | Window Closed / Lapsed |