US4394504A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Cephalosporin derivatives
Assignee: Wyeth LLC
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Filing: 1981-10-07
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Granted: 1983-07-19
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Expires: 2001-10-07
Abstract
Abstract 7-[2-(3-Amino-5-isoxazolyl)-2-alkyloxy-iminoacetamido]-ceph-3-em-4-carboxylic acid derivatives are antibacterial agents effective against gram-positive and gram-negative bacterium.
Inventors
- 👤 Thomas J. Commons
- 👤 John R. Potoski
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 16:01
CPC Classifications
C; C07; C07D; C07D261/00; C07D261/02; C07D261/06; C07D261/10; C07D261/14
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
109 words
A compound of the formula: ##STR6## in which: R 1 is H, alkyl of 1 to 4 carbon atoms, alkenyl of 2 to 4 carbon atoms, alkynyl of 2 to 4 carbon atoms, arylalkyl of 7 to 10 carbon atoms, 2-carboxyprop-2-yl, carboxymethyl, alkanoyl of 2 to 4 carbon atoms or α-phenylalkanoyl of 8 to 10 carbon atoms; R 2 is H, hydroxy, alkanoyloxy of 2 to 6 carbon atoms, carbamoyloxy, ##STR7## where R 4 is hydrogen or alkyl of 1 to 4 carbon atoms or ##STR8## where R 5 is hydrogen or alkyl of 1 to 4 carbon atoms, vinyl, sulfonyloxymethyl or carboxymethyl; or a pharmaceutically acceptable salt thereof.
Claim 2
Dependent Claim
109 words
A compound of the formula: ##STR6## in which: R 1 is H, alkyl of 1 to 4 carbon atoms, alkenyl of 2 to 4 carbon atoms, alkynyl of 2 to 4 carbon atoms, arylalkyl of 7 to 10 carbon atoms, 2-carboxyprop-2-yl, carboxymethyl, alkanoyl of 2 to 4 carbon atoms or α-phenylalkanoyl of 8 to 10 carbon atoms; R 2 is H, hydroxy, alkanoyloxy of 2 to 6 carbon atoms, carbamoyloxy, ##STR7## where R 4 is hydrogen or alkyl of 1 to 4 carbon atoms or ##STR8## where R 5 is hydrogen or alkyl of 1 to 4 carbon atoms, vinyl, sulfonyloxymethyl or carboxymethyl; or a pharmaceutically acceptable salt thereof.
Claim 3
Dependent Claim
15 words
The compound of claim 1 which is 3-acetoxymethyl-7-[2-(3-amino-5-isoxazolyl)-2-syn-methoxyiminoacetamido]-ceph-3-em-4-carboxylic acid or a pharmaceutically acceptable salt thereof.
Claim 4
Dependent Claim
15 words
The compound of claim 1 which is 3-acetoxymethyl-7-[2-(3-amino-5-isoxazolyl)-2-anti-methoxyiminoacetamido]-ceph-3-em-4-carboxylic acid or a pharmaceutically acceptable salt thereof.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-07-18 | 1987-01-17 | 1987-07-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-07-18 | 1991-01-17 | 1991-07-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-07-18 | 1995-01-17 | 1995-07-19 | $7700.00 | Window Closed / Lapsed |