US4400386A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Antimicrobial derivatives of 8-amino and 8-aminomethyl benzo(ij)quinolizine
Assignee: Riker Laboratories Inc
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Filing: 1981-11-06
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Granted: 1983-08-23
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Expires: 2001-11-06
Abstract
Abstract This invention relates to antimicrobial compounds of the formula <IMAGE> wherein X is hydrogen or fluorine; Y is selected from the group consisting of <IMAGE> <IMAGE> +TR <IMAGE> and ester, carboxylate salts, and alkylaminoalkyl ester salts thereof.
Inventors
- 👤 Richard M. Stern
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 21:05
CPC Classifications
C; C07; C07D; C07D215/00; C07D215/02; C07D215/16; C07D215/48; A; A61; A61P; A61P31/00; A61P31/04; C07D215/18; C07D215/38; C07D455/00; C07D455/03; C07D455/04
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
59 words
A compound of the formula ##STR17## wherein X is hydrogen or fluorine; Y is selected from the group consisting of ##STR18## or an alkyl or aminoalkyl ester thereof having one to four carbon atoms in the alkyl group, an aminoalkyl ester salt thereof having one to four carbon atoms in the alkyl group or a pharmaceutically-acceptable carboxylate salt thereof.
Claim 2
Dependent Claim
59 words
A compound of the formula ##STR17## wherein X is hydrogen or fluorine; Y is selected from the group consisting of ##STR18## or an alkyl or aminoalkyl ester thereof having one to four carbon atoms in the alkyl group, an aminoalkyl ester salt thereof having one to four carbon atoms in the alkyl group or a pharmaceutically-acceptable carboxylate salt thereof.
Claim 3
Dependent Claim
77 words
The compound according to claim 1 selected from the group consisting of (1) where X is hydrogen and Y is ##STR19## (2) where X is hydrogen and Y is --CH 2 NH 2 ; (3) where X is hydrogen and Y is ##STR20## (4) where X is fluoro and Y is ##STR21## (5) where X is fluoro and Y is ##STR22## and (6) where X is hydrogen and Y is --CH 2 N(CH 3 ) 2 .
Claim 4
Dependent Claim
13 words
The compound according to claims 1 or 2 which is a carboxylic acid.
Claim 5
Dependent Claim
26 words
A composition for inhibiting the growth of microorganisms comprising an effective amount of a compound according to claims 1 or 2 formulated in a pharmaceutically-acceptable vehicle.
Claim 6
Independent Claim
25 words
A method of inhibiting the growth of microorganisms comprising contacting said microorganisms with an effective amount of a compound according to claims 1 or 2.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-08-22 | 1987-02-21 | 1987-08-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-08-22 | 1991-02-21 | 1991-08-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-08-22 | 1995-02-21 | 1995-08-23 | $7700.00 | Window Closed / Lapsed |