US4409223A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Anxiolytic method
Assignee: Bristol Myers Co
•
Filing: 1982-08-06
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Granted: 1983-10-11
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Expires: 2002-08-06
Abstract
Abstract 1-(2-Pyrimidinyl)piperazine and its pharmaceutically acceptable salts are useful in the alleviation of anxiety.
Inventors
- 👤 Leslie A. Riblet
- 👤 Michael S. Eison
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 21:18
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/495; A61K31/505
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
38 words
The process for ameliorating an anxiety state in a mammal in need of such treatment comprising systemic administration to said mammal of an effective but non-toxic anxiolytic dose of 1-(2-pyrimidinyl)piperazine or a pharmaceutically acceptable acid addition salt thereof.
Claim 2
Dependent Claim
38 words
The process for ameliorating an anxiety state in a mammal in need of such treatment comprising systemic administration to said mammal of an effective but non-toxic anxiolytic dose of 1-(2-pyrimidinyl)piperazine or a pharmaceutically acceptable acid addition salt thereof.
Claim 3
Dependent Claim
45 words
The process of claim 1 wherein a pharmaceutical composition in unit dosage form suitable for systemic administration to a mammalian host is utilized which comprises a pharmaceutical carrier and an effective anxiolytic but non-toxic amount of 1-(2-pyrimidinyl)piperazine or a pharmaceutically acceptable acid addition salt thereof.
Claim 4
Dependent Claim
33 words
The process of claim 2 wherein said pharmaceutical composition comprises an amount of 1-(2-pyrimidinyl)piperazine to provide an effective anxiolytic but non-toxic dose of from 0.1 to 40 mg/kg body weight of said host.
References Cited (Backward Citations)
US3717634A
Cited
US3907801A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-10-10 | 1987-04-11 | 1987-10-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-10-10 | 1991-04-11 | 1991-10-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-10-10 | 1995-04-11 | 1995-10-11 | $7700.00 | Window Closed / Lapsed |