US4448908A
Expired / Lapsed
US
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Latex, biologically active latex conjugates and a process for their preparation
Assignee: Siemens Healthcare Diagnostics GmbH Germany
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Filing: 1982-11-12
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Granted: 1984-05-15
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Expires: 2002-11-12
Abstract
Abstract What is disclosed is a latex, reactive with a biologically active substance to form a conjugate suitable for serological or immunological assay procedures, the particles of which latex comprises a polymer core and a shell thereover, said shell comprising a water insoluble monomer of the formula ##STR1## wherein R 2 is H or CH 3 , n is 1 to 6, and R 3 and R 4 are alkyl, aryl, or same other group imparting water insolubility to said monomer.
Inventors
- 👤 Hans-Erwin Pauly
- 👤 Wolfgang Kapmeyer
- 👤 Ulrich Seitz
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 04:36
CPC Classifications
C; C08; C08F; C08F291/00; Y; Y10; Y10S; Y10S436/00; Y10S436/805; Y10S525/00; Y10S525/902
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
100 words
A latex containing particles comprising a core of a polymer of at least one ethylenically unsaturated monomer and a shell, graft polymerized to said core, of a copolymer comprising at least one ethylenic unsaturated monomer an acetal monomer of the formula ##STR3## wherein n is 1 to 6, R 2 is H or CH 3 , and R 3 and R 4 are alkyl having 2 to 6 carbon atoms, aryl, or some other inert group imparting sufficient water insolubility to said monomer to permit graft polymerization thereof to said core polymer in an aqueous latex of core polymer particles.
Claim 2
Dependent Claim
100 words
A latex containing particles comprising a core of a polymer of at least one ethylenically unsaturated monomer and a shell, graft polymerized to said core, of a copolymer comprising at least one ethylenic unsaturated monomer an acetal monomer of the formula ##STR3## wherein n is 1 to 6, R 2 is H or CH 3 , and R 3 and R 4 are alkyl having 2 to 6 carbon atoms, aryl, or some other inert group imparting sufficient water insolubility to said monomer to permit graft polymerization thereof to said core polymer in an aqueous latex of core polymer particles.
Claim 3
Dependent Claim
12 words
A latex as in claim 1 wherein said core polymer is polystyrene.
Claim 4
Dependent Claim
14 words
A latex as in claim 1 wherein said acetal monomer is methacrylamidoacetaldehyde di-n-pentyl acetal.
Claim 5
Dependent Claim
20 words
A latex as in claim 2 wherein said shell is a copolymer of methacrylamidoacetaldehyde di-n-pentyl acetal, methacrylic acid, and styrene.
Claim 6
Dependent Claim
55 words
A method for making a latex as in claim 1 which comprises graft polymerizing said acetal monomer and other shell comonomers on particles of said core polymer by mixing said monomers with an aqueous latex of said core polymer particles in the presence of a detergent, and adding a free radical initiator to said mixture.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-05-15 | 1987-11-14 | 1988-05-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-05-15 | 1991-11-14 | 1992-05-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-05-15 | 1995-11-14 | 1996-05-15 | $7700.00 | Window Closed / Lapsed |