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US4544455A Expired / Lapsed US ⏱️ 0.0 years remaining

Salt bridge liquid

Assignee: Radiometer AS
•
Filing: 1983-05-17
•
Granted: 1985-10-01
•
Expires: 2003-05-17
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Abstract

Abstract Salt bridge liquid for use in potentiometric measurement of blood or a blood liquid. The salt bridge liquid contains Na + -ions and HCOO - -ions in substantially equimolar amounts, preferably in a concentration larger than or equal to 1 M, in particular about 4 M. When this salt bridge liquid is used, the potentiometric measurement will give corresponding results when measuring a blood sample and the corresponding plasma sample because the suspension effect which is caused by the erythrocytes and which is seen when using other salt bridge liquids is substantially eliminated. Furthermore, different blood samples with the same ion concentration but with varying erythrocyte content will give corresponding measuring results.

Inventors

  • 👤 Anne R. Eisenhardt
  • 👤 Ole J. Jensen

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-30 03:55
CPC Classifications
G; G01; G01N; G01N27/00; G01N27/26; G01N27/28; G01N27/401; C; C07; C07C; C07C53/00; C07C53/02; C07C53/06; G01N33/00; G01N33/48; G01N33/483; G01N33/487; G01N33/49

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 82 words
A method for the determination of the concentration of an ion in a sample of blood or blood liquid, using a measuring chain comprising an ion-sensitive indicator electrode and a reference electrode in which the ion-sensitive indicator electrode is brought into contact with the sample and the reference electrode is brought into contact with a salt bridge liquid which, through a liquid junction, is in contact with the sample, the salt bridge liquid used containing Na + -ions and HCOO - ions.
Claim 2
Independent Claim 82 words
A method for the determination of the concentration of an ion in a sample of blood or blood liquid, using a measuring chain comprising an ion-sensitive indicator electrode and a reference electrode in which the ion-sensitive indicator electrode is brought into contact with the sample and the reference electrode is brought into contact with a salt bridge liquid which, through a liquid junction, is in contact with the sample, the salt bridge liquid used containing Na + -ions and HCOO - ions.
Claim 3
Dependent Claim 34 words
A method as claimed in claim 1 wherein the salt bridge liquid contains Na + -ions and HCOO - -ions in substantially equimolar amounts in a concentration of more than or equal to 1M.
Claim 4
Dependent Claim 34 words
A method as claimed in claim 2 wherein the salt bridge liquid contains Na + -ions and HCOO - -ions in substantially equimolar amounts in a concentration of more than or equal to 1.5M.
Claim 5
Dependent Claim 30 words
A method as claimed in claim 2 wherein the salt bridge liquid contains Na + -ions and HCOO - -ions in substantially equimolar amounts in a concentration of about 4M.
Claim 6
Independent Claim 40 words
A method as claimed in claims 1 wherein the ion whose concentration is determined is K + , Na + , Ca ++ , Mg ++ , Li + , H + , HCO 3 - or Cl - .
Claim 7
Dependent Claim 22 words
A method as claimed in claim 1, wherein the salt bridge solution consists essentially of an aqueous about 4M solution of HCOONa.

References Cited (Backward Citations)

US3556950A Cited
US3833495A Cited
US3997420A Cited
US3874850A Cited
US3972614A Cited
US4160714A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1988-09-30 1989-04-01 1989-10-01 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1992-09-30 1993-04-01 1993-10-01 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1996-09-30 1997-04-01 1997-10-01 $7700.00 Window Closed / Lapsed

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