US4587351A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Synthesis of ketones with calcium hypochlorite
Assignee: Eli Lilly and Co
•
Filing: 1984-04-18
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Granted: 1986-05-06
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Expires: 2004-04-18
Abstract
Abstract The present invention pertains to a process for preparing ketones employing a silica catalyzed oxidation of a secondary alcohol with calcium hypochlorite in acetonitrile.
Inventors
- 👤 Randall K. Atkins
- 👤 Leland O. Weigel
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 17:05
CPC Classifications
C; C07; C07D; C07D319/00; C07D319/04; C07D319/08
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
43 words
A process for preparing a compound of the formula ##STR4## comprising reacting a secondary alcohol of the formula ##STR5## with calcium hypochlorite in acetonitrile in the presence of silica at a temperature in the range of about 15° C. to about 35° C.
Claim 2
Dependent Claim
43 words
A process for preparing a compound of the formula ##STR4## comprising reacting a secondary alcohol of the formula ##STR5## with calcium hypochlorite in acetonitrile in the presence of silica at a temperature in the range of about 15° C. to about 35° C.
Claim 3
Dependent Claim
25 words
A process of claim 1 wherein the reaction is conducted at a temperature in the range of from about 20° C. to about 25° C.
Claim 4
Dependent Claim
18 words
A process of claim 1 wherein one gram of silica is used for each gram of secondary alcohol.
Claim 5
Dependent Claim
19 words
a process of claim 1 wherein one gram of calcium hypochlorite is used for each gram of secondary alcohol.
Claim 6
Dependent Claim
17 words
A process of claim 1 wherein the reaction is conducted in the presence of an unreactive base.
Claim 7
Dependent Claim
11 words
A process of claim 5 wherein the unreactive base is inorganic.
Claim 8
Dependent Claim
12 words
A process of claim 6 wherein the inorganic base is sodium bicarbonate.
References Cited (Backward Citations)
US3331856A
Cited
US4198415A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-05-05 | 1989-11-04 | 1990-05-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-05-05 | 1993-11-04 | 1994-05-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-05-05 | 1997-11-04 | 1998-05-06 | $7700.00 | Window Closed / Lapsed |