Disinfectant solution for contact lens

Claim 2

An aqueous solution for disinfecting soft contact lenses comprising the reaction product of an organosilicon quaternary ammonium salt of the formula: ##STR22## where Y is a hydrolyzable radical, which is alkoxy, or acyloxy; R is a monovalent hydrocarbon group, which is lower alkyl or phenyl; a is 0-2; Q is a divalent hydrocarbon radical, which is alkylene or phenylene; m is 1-20; R' is alkyl C 1 -C 18 , aryl, alkaryl, or aralkyl; R" is lower alkyl; n is 9-17; X is monovalent inorganic or organic radical or group selected from the group consisting of halogen; triiodide; acyloxy; or YSO 4 , where Y is a monovalent hydrocarbon, hydrogen, and --(CH 2 --) x --COOR'", where x is at least 2 and R"' is a monovalent hydrocarbon group free of unsaturation with about 75-99 wt % of a water soluble organic polymer reactive with said hydrolyzable group and having a molecular weight sufficient to prevent the reaction product from being adsorbed into or penetrating the soft contact lens.

Claim 3

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said polymer has a molecular weight of at least 7,500.

Claim 4

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said reaction product comprises 0.001-0.5 wt % of said solution.

Claim 5

An aqueous solution for disinfecting soft contact lenses according to claim 1 which the organosilicon compound is present in an amount of 5-15 wt % of said reaction product.

Claim 6

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said salt is a halide, triiodide or sulfate.

Claim 7

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said hydrolyzable group is an alkoxy group.

Claim 8

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said water soluble polymer is selected from the group consisting of polyacrylamides, polymethacrylamides, polydiacetoneacrylamides, polyacrylic acids, polymethacrylic acids, polyhydroxy alkacrylates, polyhydroxyalkylmethacrylates, carboxymethylcellulose, hydroxymethylcellulose, polyaminoalkylacrylates, polyaminoalkylmethacrylates, polyamines, polyalkylene oxides, hydrophilic polyesters, hydrophilic polyamides, polyvinylpyrrolidone, polyvinylalcohol, polyethylene sulfonic acid and polystyrene sulfonic acid.

Claim 9

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein Y is methoxy, R is methyl, a is 0-2, and m is 3, and X is halogen or triiodide.

Claim 10

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said polymer is polyvinylpyrrolidone, polyvinylalcohol or carboxymethylcellulose.

Claim 11

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said organosilicon compound is 3-(trimethoxysilyl)propyloctadecyldimethyl ammonium chloride.

Claim 12

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said organosilicon compound is 3-(triethoxysilyl)propyloctadecyldimethyl ammonium chloride.

Claim 13

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said organosilicon compound is 3-(methyldimethoxysilyl)propyloctadecyldimethyl ammonium chloride.

Claim 14

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said organosilicon compound is 3-(phenyldimethoxysilyl)propyloctadecyldimethyl ammonium chloride.

Claim 15

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said organosilicon compound is 3-(dimethylmethoxysilyl)propyloctadecyldimethyl ammonium chloride.

Claim 16

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said organosilicon compound is 3-(diphenylmethoxysilyl)propyloctadecyldimethyl ammonium chloride.

Claim 17

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said organosilicon compound is 6-(methyldimethoxy)hexyloctadecyldimethyl ammonium chloride.

Claim 18

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said organosilicon compound is 8-(methyldimethoxysilyl)octyloctadecyldimethyl ammonium chloride.

Claim 19

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said organosilicon compound is 12-(methyldimethoxysilyl)dodecyloctadecyldimethyl ammonium chloride.

Claim 20

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said organosilicon compound is 3-(methyldimethoxysilyl)propylmethyldidodecyl ammonium chloride.

Claim 21

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said organosilicon compound is 3-(methyldimethoxysilyl)propylmethyldodecylbenzyl ammonium chloride.

Claim 22

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said organosilicon compound is 3-(methyldimethoxysilyl)propylbenzyldidodecyl ammonium chloride.

Claim 23

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said organosilicon compound is 3-(trimethoxysilyl)propyloctadecyldimethyl ammonium bromide.

Claim 24

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said organosilicon compound is 3-(trimethoxysilyl)propyloctadecyldimethyl ammonium triiodide.

Claim 25

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said organosilicon compound is 3-(trimethoxysilyl)propyloctadecyldimethyl ammonium acetate.

Claim 26

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said organosilicon compound is 3-(trimethoxysilyl)propyloctadecyldimethyl ammonium sulfate.

Claim 27

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said organosilicon compound is 3-(methoxydimethylsilyl)propylmethyldidodecyl ammonium triiodide.

Claim 28

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said organosilicon compound is 2-(trimethoxysilyl)ethyl p-benzyl dimethyloctadecyl ammonium chloride.

Claim 29

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said organosilicon compound is 2-(trimethoxysilyl)ethyl-4-methylcyclohexyl dimethyl octadecyl ammonium chloride.

Claim 30

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said polymer has a reactive hydrogen therein.

Claim 31

An aqueous solution for disinfecting soft contact lenses according to claim 1 wherein said polymer has a molecular weight of at least 10,000.

Claim 32

A method of disinfecting soft contact lenses which comprises applying to the lens the aqueous solution of claim 1.

Claim 33

The reaction product, which is effective as a disinfectant particularly for soft contact lenses, which results from the reaction of (i) about 1-25 wt % of an anti-microbial organosilicon quaternary ammonium salt which has the formula: ##STR23## where: Y is a hydrolyzable radical; which is alkoxy or acyloxy; R is a monovalent hydrocarbon group which is lower alkyl or phenyl; a is 0-2; Q is a divalent hydrocarbon radical which is alkylene or phenylene; m is 1-20; R' is alkyl C 1 -C 18 , aryl, alkaryl, or aralkyl; R" is lower alkyl; n is 9-17; X is a monovalent inorganic or organic radical or group selected from halogen, triiodide, acyloxy or YSO 4 ; where Y is a monovalent hydrocarbon, hydrogen, or --(CH 2 ) x --COOR"', where x is at least 2, and R"' is a monovalent hydrocarbon group free of unsaturation; with: (ii) about 75-99 wt % of a water soluble organic polymer reactive with said hydrolyzable group and having a molecular weight sufficient to prevent the reaction product from being absorbed or penetrating a soft contact lens, wherein said polymer is selected from the group consisting of polyacrylamides, polymethacrylamides, polydiacetoneacrylamides, polyacrylic acids, polymethacrylic acids, polyhydroxy alkacrylates, polyhydroxyalkylmethacrylates, carboxymethylcellulose, hydroxymethylcellulose, polyaminoalkylacrylates, polyaminoalkylmethacrylates, polyamines, polyalkylene oxides, hydrophilic polyesters, hydrophilic polyamides, polyvinylpyrrolidone, polyvinylalchohol, polyethylene sulfonic acid and polystyrene sulfonic acid.

Claim 34

The reaction product, which is effective as a disinfectant particularly for soft contact lenses, which results from the reaction of (i) about 1-25 wt % of an anti-microbial organosilicon quaternary ammonium salt which has the formula: ##STR23## where: Y is a hydrolyzable radical; which is alkoxy or acyloxy; R is a monovalent hydrocarbon group which is lower alkyl or phenyl; a is 0-2; Q is a divalent hydrocarbon radical which is alkylene or phenylene; m is 1-20; R' is alkyl C 1 -C 18 , aryl, alkaryl, or aralkyl; R" is lower alkyl; n is 9-17; X is a monovalent inorganic or organic radical or group selected from halogen, triiodide, acyloxy or YSO 4 ; where Y is a monovalent hydrocarbon, hydrogen, or --(CH 2 ) x --COOR"', where x is at least 2, and R"' is a monovalent hydrocarbon group free of unsaturation; with: (ii) about 75-99 wt % of a water soluble organic polymer reactive with said hydrolyzable group and having a molecular weight sufficient to prevent the reaction product from being absorbed or penetrating a soft contact lens, wherein said polymer is selected from the group consisting of polyacrylamides, polymethacrylamides, polydiacetoneacrylamides, polyacrylic acids, polymethacrylic acids, polyhydroxy alkacrylates, polyhydroxyalkylmethacrylates, carboxymethylcellulose, hydroxymethylcellulose, polyaminoalkylacrylates, polyaminoalkylmethacrylates, polyamines, polyalkylene oxides, hydrophilic polyesters, hydrophilic polyamides, polyvinylpyrrolidone, polyvinylalchohol, polyethylene sulfonic acid and polystyrene sulfonic acid.

Claim 35

Reaction products according to claim 32 in which said polymer has a molecular weight of at least 7,500.

Claim 36

Reaction products according to claim 32 in which the organosilicon compound is present in an amount of 5-15 wt % of said reaction product.

Claim 37

Reaction products according to claim 32 wherein said salt is a halide, triiodide, sulfate or carboxylate.

Claim 38

Reaction products according to claim 32 wherein said hydrolyzable group is an alkoxy group.

Claim 39

Reaction products according to claim 32 wherein said polymer is polyvinylpyrrolidone, polyvinylalcohol or carboxymethylcellulose.