Patent US3891871A successfully refreshed from Google Patents.
US4618486A
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Monoclonal antibody formulation for diagnostic use
Assignee: ARLOCK CONSULTING AB
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Filing: 1984-01-12
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Granted: 1986-10-21
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Expires: 2004-01-12
Abstract
Abstract Aqueous formulation containing monoclonal antibodies active against cell-bound antigens, particularly human red cell antigens, the said formulation containing a soluble salt in a concentration of not less than about 200 mmoles/1.
Inventors
- 👤 Karl A. Lundblad
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 19:24
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/80; Y; Y10; Y10S; Y10S435/00; Y10S435/962; Y10S436/00; Y10S436/807; Y10S436/808; Y10S436/826
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
77 words
A method for identifying ABO blood groups comprising contacting a member selected from the group consisting of whole red cells, red cell membranes and soluble group substances with an aqueous formulation comprising monoclonal antibodies active against cell-bound antigens of blood group A, B or AB and a soluble salt selected from the group consisting of salts of the alkali and alkaline earth metals in a concentration within the range of from 250 mmoles/liter to about 650 mmoles/liter.
Claim 2
Independent Claim
77 words
A method for identifying ABO blood groups comprising contacting a member selected from the group consisting of whole red cells, red cell membranes and soluble group substances with an aqueous formulation comprising monoclonal antibodies active against cell-bound antigens of blood group A, B or AB and a soluble salt selected from the group consisting of salts of the alkali and alkaline earth metals in a concentration within the range of from 250 mmoles/liter to about 650 mmoles/liter.
Claim 3
Dependent Claim
22 words
A method according to claim 1, wherein said concentration is within the range of from about 350 m moles/liter to 550 mmoles/liter.
Claim 4
Dependent Claim
15 words
A method according to claim 1, wherein said salt is selected from the alkali metals.
Claim 5
Dependent Claim
14 words
A method according to claim 3, wherein said salt has a halide counter ion.
Claim 6
Dependent Claim
28 words
A method according to claim 1, wherein said salt is selected from the group consisting of NaCl, KCl, CaCl 2 , KI, MgCl 2 and MgSO 4 .
Claim 7
Dependent Claim
11 words
A method according to claim 5, wherein said salt is NaCl.
Claim 8
Dependent Claim
17 words
A method according to claim 1, wherein the aqueous formulation is in the form of a solution.
Claim 9
Dependent Claim
25 words
A method according to claim 7, wherein the aqueous formulation is in the form of a solution and wherein the soluble salt is sodium chloride.
Claim 10
Dependent Claim
52 words
An aqueous formulation comprising monoclonal antibodies active against cell-bound antigens of blood group A, B or AB and a soluble salt selected from the group consisting of NaCl, KCl, CaCl 2 , KI, MgCl 2 and MgSO 4 in a concentration within the range of from 250 mmoles/liter to about 650 mmoles/liter.
Claim 11
Dependent Claim
52 words
An aqueous formulation comprising monoclonal antibodies active against cell-bound antigens of blood group A, B or AB and a soluble salt selected from the group consisting of NaCl, KCl, CaCl 2 , KI, MgCl 2 and MgSO 4 in a concentration within the range of from 250 mmoles/liter to about 650 mmoles/liter.
References Cited (Backward Citations)
US4164558A
Cited
WO1982003462A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-10-20 | 1990-04-21 | 1990-10-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-10-20 | 1994-04-21 | 1994-10-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-10-20 | 1998-04-21 | 1998-10-21 | $7700.00 | Window Closed / Lapsed |