US4672030A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Test kit for the determination of activated thromboplastin time (PTT) with increased sensitivity to heparin
Assignee: Goedecke GmbH
•
Filing: 1985-02-15
•
Granted: 1987-06-09
•
Expires: 2005-02-15
Abstract
Abstract Partial thromboplastin time (PTT) is determined for monitoring and controlling heparin therapy with a test kit having increased sensitivity to heparin. Increased sensitivity is obtained by including with reagents in the test kit an organic sulfuric acid or salt thereof such as dodecylbenzenesulfuric acid--sodium salt and/or an organic sulfuric acid ester or salt thereof such as sodium laurylsulfate.
Inventors
- 👤 Peter Witt
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 20:52
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/86; G01N2400/00; G01N2400/10; G01N2400/38; G01N2400/40; Y; Y10; Y10S; Y10S435/00; Y10S435/81
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
68 words
A test kit for the determination of PTT containing test reagents comprising a PTT reagent and, in addition, at least one compound of the formula R--O--SO.sub.3 X or R--SO.sub.3 X in which R is a mono or polyunsaturated straight-chained or branched aliphatic or cycloaliphatic hydrocarbon residue, which may be substituted, or an aromatic residue which also may be substituted and X represents a hydrogen atom or a cation.
Claim 2
Dependent Claim
68 words
A test kit for the determination of PTT containing test reagents comprising a PTT reagent and, in addition, at least one compound of the formula R--O--SO.sub.3 X or R--SO.sub.3 X in which R is a mono or polyunsaturated straight-chained or branched aliphatic or cycloaliphatic hydrocarbon residue, which may be substituted, or an aromatic residue which also may be substituted and X represents a hydrogen atom or a cation.
Claim 3
Dependent Claim
44 words
Test kit according to claim 1, wherein the compound of the formula R--O--SO 3 X or R--SO 3 X is present in such quantity that 1 liter of a reconstituted solution of the test reagents will contain 0.05 to 100 mmol of said compound.
Claim 4
Dependent Claim
44 words
Test kit according to claim 2, wherein the compound of the formula R--O--SO 3 X or R--SO 3 X is present in such quantity that 1 liter of a reconstituted solution of the test reagents will contain 0.2 to 20 mmol of said compound.
Claim 5
Dependent Claim
14 words
Test kit according to claim 1 wherein said compound is dodecylbenzenesulfonic acid-Na-salt or sodiumlaurylsulfate.
Claim 6
Dependent Claim
24 words
Test kit according to claim 1 wherein the compound of the formula R--O--SO 3 X or R--SO 3 X is in a reconstituted solution.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-06-08 | 1990-12-08 | 1991-06-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-06-08 | 1994-12-08 | 1995-06-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-06-08 | 1998-12-08 | 1999-06-09 | $7700.00 | Window Closed / Lapsed |