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US4687423A Expired / Lapsed US ⏱️ 0.0 years remaining

Electrochemically-driven pulsatile drug dispenser

Assignee: CareFusion 303 Inc
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Filing: 1985-06-07
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Granted: 1987-08-18
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Expires: 2005-06-07
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Abstract

Abstract An improved drug dispenser for the pulsatile or peristaltic delivery of drugs. The drug dispenser includes a fluid reservoir for storing the drug to be dispensed, an electrochemical pump for pumping the drug from the fluid reservoir, and a pump valve responsive to the pump pressure such that when the pump pressure reaches some predetermined value, the pump valve releases the pressure exerted upon the drug. The result is a low cost, low weight ad efficient drug dispenser for the pulsatile delivery of drugs.

Inventors

  • 👤 Henri J. R. Maget
  • 👤 Paul Krejci

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-04 07:43
CPC Classifications
A; A61; A61M; A61M5/00; A61M5/14; A61M5/142; A61M5/14244; A61M5/14276; A61M2005/14204

Claims Analysis

Total Claims: 18
Claim 1
Independent Claim 176 words
An electrochemically-driven pulsatile drug dispenser, comprising: a pump chamber having a pump inlet and a pump outlet; an electrochemical pump for pumping a motive fluid, said electrochemical pump having a motive fluid inlet and a motive fluid outlet; pressure transmission means disposed between said pump chamber and said motive fluid outlet, said pressure transmission means being displaced in response to pressure of said motive fluid at said motive fluid outlet; and a pump valve having a valve inlet in fluid communication with said motive fluid outlet and a valve outlet in fluid communication with said motive fluid inlet, said pump valve being responsive to said motive fluid pressure whereby said pump valve releases said motive fluid pressure exerted upon said pressure transmission means when said motive fluid pressure reaches a predetermined value, wherein the pump valve includes: a pump valve seat; and a pump valve diaphragm having a perforation, wherein the pump valve diaphragm moves upward from the pump valve seat and, at the predetermined value, snaps open and releases the pump pressure through the perforation.
Claim 2
Dependent Claim 176 words
An electrochemically-driven pulsatile drug dispenser, comprising: a pump chamber having a pump inlet and a pump outlet; an electrochemical pump for pumping a motive fluid, said electrochemical pump having a motive fluid inlet and a motive fluid outlet; pressure transmission means disposed between said pump chamber and said motive fluid outlet, said pressure transmission means being displaced in response to pressure of said motive fluid at said motive fluid outlet; and a pump valve having a valve inlet in fluid communication with said motive fluid outlet and a valve outlet in fluid communication with said motive fluid inlet, said pump valve being responsive to said motive fluid pressure whereby said pump valve releases said motive fluid pressure exerted upon said pressure transmission means when said motive fluid pressure reaches a predetermined value, wherein the pump valve includes: a pump valve seat; and a pump valve diaphragm having a perforation, wherein the pump valve diaphragm moves upward from the pump valve seat and, at the predetermined value, snaps open and releases the pump pressure through the perforation.
Claim 3
Dependent Claim 19 words
The electrochemically-driven pulsatile drug dispenser as defined in claim 1, and further comprising: a reservoir for storing the drug.
Claim 4
Dependent Claim 26 words
The electrochemically-driven pulsatile drug dispenser as defined in claim 2, wherein the electrochemical pump includes: an electrochemical cell for pressurizing a gas as said motive fluid.
Claim 5
Dependent Claim 31 words
The electrochemically-driven pulsatile drug dispenser as defined in claim 3, wherein the electrochemical cell includes: an electrolytic membrane; and a pair of electrodes disposed on either side of the electrolytic membrane.
Claim 6
Dependent Claim 31 words
The electrochemically-driven pulsatile drug dispenser as defined in claim 3, wherein said pressure transmission means comprises: a flexible diaphragm for exerting the gas pressure on a drug in the pump chamber.
Claim 7
Dependent Claim 196 words
A pulsatile drug dispenser, comprising: a pump chamber for containing a drug, said pump chamber having a pump inlet and a pump outlet; means for pressurizing a motive fluid, said means having a motive fluid inlet and a motive fluid outlet; pressure transmission means disposed between said pump chamber and said motive fluid outlet, said pressure transmission means being displaced in response to pressure of said motive fluid at said motive fluid outlet for pumping said drug from said pump chamber; pressure responsive means having an inlet in fluid communication with said motive fluid outlet and an outlet in fluid communication with said motive fluid inlet, said pressure responsive means being responsive to said motive fluid pressure whereby said pressure responsive means releases said motive fluid pressure exerted upon said pressure transmission means when said motive fluid pressure reaches a predetermine value, thereby pumping said drug in a pulsatile or peristaltic motion, wherein the pressure responsive means includes: a pump valve seat; and a pump valve diaphragm having a perforation, wherein the pump valve diaphragm moves upward from the pump valve seat and, at the predetermined value, snaps open and releases the fluid through the perforation.
Claim 8
Dependent Claim 196 words
A pulsatile drug dispenser, comprising: a pump chamber for containing a drug, said pump chamber having a pump inlet and a pump outlet; means for pressurizing a motive fluid, said means having a motive fluid inlet and a motive fluid outlet; pressure transmission means disposed between said pump chamber and said motive fluid outlet, said pressure transmission means being displaced in response to pressure of said motive fluid at said motive fluid outlet for pumping said drug from said pump chamber; pressure responsive means having an inlet in fluid communication with said motive fluid outlet and an outlet in fluid communication with said motive fluid inlet, said pressure responsive means being responsive to said motive fluid pressure whereby said pressure responsive means releases said motive fluid pressure exerted upon said pressure transmission means when said motive fluid pressure reaches a predetermine value, thereby pumping said drug in a pulsatile or peristaltic motion, wherein the pressure responsive means includes: a pump valve seat; and a pump valve diaphragm having a perforation, wherein the pump valve diaphragm moves upward from the pump valve seat and, at the predetermined value, snaps open and releases the fluid through the perforation.
Claim 9
Dependent Claim 18 words
The pulsatile drug dispenser as defined in a claim 6, and further comprising: means for storing the drug.
Claim 10
Dependent Claim 25 words
The pulsatile drug dispenser as defined in claim 6, wherein the means for pressurizing a motive fluid includes: an electrochemical cell for pressurizing the fluid.
Claim 11
Dependent Claim 30 words
The pulsatile drug dispenser as defined in claim 8, wherein the electrochemical cell includes: an electrolytic membrane; and a pair of electrodes disposed on either side of the electrolytic membrane.
Claim 12
Dependent Claim 31 words
The pulsatile drug dispenser as defined in claim 8, wherein said pressure transmission means comprises: a flexible diaphragm for exerting the motive fluid pressure on the drug in the pump chamber.
Claim 13
Dependent Claim 185 words
An electrochemically drive pulsatile drug dispenser, comprising: a housing; a pump chamber disposed in said housing and having a pump inlet and a pump outlet; an electrochemical pump disposed in said housing for pumping a gaseous motive fluid, said electrochemical pump having a motive fluid inlet and a motive fluid outlet; pressure transmission means disposed in said housing between said pump chamber and said motive fluid outlet, said pressure transmission means being displaced in response to pressure of said motive fluid at said motive fluid outlet; a pump valve having a valve inlet and having a valve outlet in fluid communication with said motive fluid inlet; and a fluid conduit in said housing having an outlet end in fluid communication with said valve inlet and having an inlet end in fluid communication with said motive fluid exerting pressure upon said pressure transmission means, said inlet end being isolated from said motive fluid outlet, whereby said pump valve is responsive to said motive fluid pressure and releases said motive fluid pressure exerted upon said pressure transmission means when said motive fluid pressure reaches a predetermined value.
Claim 14
Dependent Claim 185 words
An electrochemically drive pulsatile drug dispenser, comprising: a housing; a pump chamber disposed in said housing and having a pump inlet and a pump outlet; an electrochemical pump disposed in said housing for pumping a gaseous motive fluid, said electrochemical pump having a motive fluid inlet and a motive fluid outlet; pressure transmission means disposed in said housing between said pump chamber and said motive fluid outlet, said pressure transmission means being displaced in response to pressure of said motive fluid at said motive fluid outlet; a pump valve having a valve inlet and having a valve outlet in fluid communication with said motive fluid inlet; and a fluid conduit in said housing having an outlet end in fluid communication with said valve inlet and having an inlet end in fluid communication with said motive fluid exerting pressure upon said pressure transmission means, said inlet end being isolated from said motive fluid outlet, whereby said pump valve is responsive to said motive fluid pressure and releases said motive fluid pressure exerted upon said pressure transmission means when said motive fluid pressure reaches a predetermined value.
Claim 15
Dependent Claim 54 words
The electrochemically-driven pulsatile drug dispenser as defined in claim 11, wherein the pump valve comprises: a pump valve seat; and a pump valve diaphragm having a perforation, wherein the pump valve diaphragm moves upward from the pump valve seat and, at the predetermined value, snaps open and releases the pump pressure through the perforation.
Claim 16
Dependent Claim 32 words
The electrochemically-driven pulsatile drug dispenser as defined in claim 11, wherein said pressure transmission means comprises a flexible diaphragm for exerting said motive fluid pressure on a drug in said pump chamber.
Claim 17
Dependent Claim 17 words
The electrochemically-driven pulsatile drug dispenser as defined in claim 13, wherein the gaseous motive fluid comprises air.
Claim 18
Dependent Claim 38 words
The electrochemically-driven pulsatile drug dispenser as defined in claim 14, further comprising an air conduit in said housing establishing communication between said motive fluid inlet and ambient atmosphere, whereby said motive fluid comprises air from said ambient atmosphere.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1990-08-17 1991-02-16 1991-08-18 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1994-08-17 1995-02-16 1995-08-18 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1998-08-17 1999-02-16 1999-08-18 $7700.00 Window Closed / Lapsed

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