US4687929A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Monodisperse aerosol generator
Assignee: Georgia Tech Research Corp
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Filing: 1985-09-11
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Granted: 1987-08-18
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Expires: 2005-09-11
Abstract
Abstract A monodisperse aerosol generator forms a stable jet of liquid at a velocity allowing columnar breakup into droplets of uniform size and spacing. To prevent degradation of the monodisperse aerosol, it is dispersed by entrainment in a high velocity gaseous stream. To provide an interface for direct injection into a mass spectrometer or to interface a liquid chromatograph with a mass spectrometer, the generator is followed by a desolvation chamber operating at about atmospheric pressure and a multistage pressure reducer which evacuates solvent vapor and gaseous medium to form a high momentum, solvent-depleted solute aerosol beam which is input into the mass spectrometer.
Inventors
- 👤 Richard F. Browner
- 👤 Ross C. Willoughby
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 19:22
CPC Classifications
H; H01; H01J; H01J49/00; H01J49/02; H01J49/04; H01J49/0431; H01J49/0445; H01J49/045; B; B01; B01F; B01F23/00; B01F23/20; B01F23/21; B01F23/211; B05; B05B; B05B1/00; B05B1/02; G; G01; G01N; G01N30/00; G01N30/02; G01N30/62; G01N30/72; G01N30/7233; G01N30/724; G01N30/7246; G01N30/7293; G01N30/7206; G01N30/7213; G01N30/74
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
121 words
A method of introducing solute recovered from effluent of a liquid chromatograph into a mass spectrometer, which comprises the steps of: (a) generating a monodisperse aerosol of predetermined uniform droplet size from the effluent by delivering the effluent through a conduit at a velocity such that monodisperse droplet formation occurs in the absence of outside disturbances; (b) providing a dispersing gas; (c) dispersing the droplets with gas just after droplet formation; (d) entraining the aerosol in qas and desolvating the aerosol at substantially atmospheric pressure; (e) expanding the components of step (d) into a low pressure environment while removing gas therefrom to form a high momentum monodisperse aerosol beam of solute particles; and (f) directing said beam into a mass spectrometer.
Claim 2
Independent Claim
121 words
A method of introducing solute recovered from effluent of a liquid chromatograph into a mass spectrometer, which comprises the steps of: (a) generating a monodisperse aerosol of predetermined uniform droplet size from the effluent by delivering the effluent through a conduit at a velocity such that monodisperse droplet formation occurs in the absence of outside disturbances; (b) providing a dispersing gas; (c) dispersing the droplets with gas just after droplet formation; (d) entraining the aerosol in qas and desolvating the aerosol at substantially atmospheric pressure; (e) expanding the components of step (d) into a low pressure environment while removing gas therefrom to form a high momentum monodisperse aerosol beam of solute particles; and (f) directing said beam into a mass spectrometer.
References Cited (Backward Citations)
US2887181A
Cited
US2966312A
Cited
US3421692A
Cited
US3633027A
Cited
US3997298A
Cited
US4055987A
Cited
US4112297A
Cited
US4066411A
Cited
US4209696A
Cited
US4268460A
Cited
US4298795A
Cited
US4213326A
Cited
US4403147A
Cited
US4281246A
Cited
US4300044A
Cited
US4391778A
Cited
US4531056A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-08-17 | 1991-02-16 | 1991-08-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-08-17 | 1995-02-16 | 1995-08-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-08-17 | 1999-02-16 | 1999-08-18 | $7700.00 | Window Closed / Lapsed |