US4724232A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Treatment of human viral infections
Assignee: SmithKline Beecham Corp
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Filing: 1985-09-17
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Granted: 1988-02-09
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Expires: 2005-09-17
Abstract
Abstract Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof. Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
Inventors
- 👤 Janet L. Rideout
- 👤 David W. Barry
- 👤 Sandra N. Lehrman
- 👤 Martha H. St. Clair
- 👤 Phillip A. Furman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 18:44
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70; A61K31/7042; A61K31/7052; A61K31/706; A61K31/7064; A61K31/7068; A61K31/7072; A61K38/00; A61K38/16; A61K38/17; A61K38/19; A61K38/21; A61K38/212; C; C07; C07H; C07H19/00; C07H19/02; C07H19/04; C07H19/06; C07H19/10; Y; Y10; Y10S; Y10S424/00; Y10S424/15
Claims Analysis
Total Claims: 30
Claim 1
Independent Claim
27 words
A method of treating a human having acquired immunodeficiency syndrome comprising the oral administration of an effective acquired immunodeficiency syndrome treatment amount of 3'-azido-3'-deoxythymidine to said human.
Claim 2
Independent Claim
27 words
A method of treating a human having acquired immunodeficiency syndrome comprising the oral administration of an effective acquired immunodeficiency syndrome treatment amount of 3'-azido-3'-deoxythymidine to said human.
Claim 3
Dependent Claim
14 words
The method of claim 1 in which a capsule containing 3'-azido-3'-deoxythymidine is orally administered.
Claim 4
Dependent Claim
14 words
The method of claim 1 in which a tablet containing 3'-azido-3'-deoxythymidine is orally administered.
Claim 5
Dependent Claim
15 words
The method of claim 1 in which an aqueous solution containing 3'-azido-3'-deoxythymidine is orally administered.
Claim 6
Dependent Claim
15 words
The method of claim 1 in which an aqueous suspension containing 3'-azido-3'-deoxythymidine is orally administered.
Claim 7
Dependent Claim
15 words
The method of claim 1 in which a non-aqueous suspension containing 3'-azido-3'-deoxythymidine is orally administered.
Claim 8
Independent Claim
32 words
A method of treating a human having acquired immunodeficiency syndrome comprising the parenteral administration of an effective acquired immunodeficiency syndrome treatment amount of 3'-azido-3'-deoxythymidine in a sterile injectable formulation to said human.
Claim 9
Independent Claim
32 words
A method of treating a human having acquired immunodeficiency syndrome comprising the parenteral administration of an effective acquired immunodeficiency syndrome treatment amount of 3'-azido-3'-deoxythymidine in a sterile injectable formulation to said human.
Claim 10
Independent Claim
38 words
A method of treating a human having acquired immunodeficiency syndrome comprising the administration of an effective acquired immunodeficiency syndrome treatment amount of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable alkali metal, alkaline earth or ammonium salt thereof to said human.
Claim 11
Independent Claim
38 words
A method of treating a human having acquired immunodeficiency syndrome comprising the administration of an effective acquired immunodeficiency syndrome treatment amount of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable alkali metal, alkaline earth or ammonium salt thereof to said human.
Claim 12
Dependent Claim
17 words
The method of claim 8 in which 3'-azido-3'-deoxythymidine or the salt thereof is administered orally or parenterally.
Claim 13
Dependent Claim
11 words
The method of claim 9 in which the salt is administered.
Claim 14
Dependent Claim
22 words
The method of claim 9 in which a tablet, capsule or sterile injectable formulation containing 3'-azido-3'-deoxythymidine or said salt thereof is administerable.
Claim 15
Dependent Claim
19 words
The method of claim 8 in which an aqueous or non-aqueous solution or suspension containing 3'-azido-3'-deoxythymidine is orally administered.
Claim 16
Independent Claim
31 words
A method of treating a human having acquired immunodeficiency syndrome related complex comprising the oral administration of an effective acquired immunodeficiency syndrome related complex treatment amount of 3'-azido-3'-deoxythymidine to said human.
Claim 17
Independent Claim
31 words
A method of treating a human having acquired immunodeficiency syndrome related complex comprising the oral administration of an effective acquired immunodeficiency syndrome related complex treatment amount of 3'-azido-3'-deoxythymidine to said human.
Claim 18
Dependent Claim
14 words
The method of claim 13 in which a capsule containing 3'-azido-3'-deoxythymidine is orally administered.
Claim 19
Dependent Claim
14 words
The method of claim 13 in which a tablet containing 3'-azido-3'-deoxythymidine is orally administered.
Claim 20
Dependent Claim
15 words
The method of claim 13 in which an aqueous solution containing 3'-azido-3'-deoxythymidine is orally administered.
Claim 21
Dependent Claim
15 words
The method of claim 13 in which an aqueous suspension containing 3'-azido-3'-deoxythymidine is orally administered.
Claim 22
Dependent Claim
15 words
The method of claim 13 in which a non-aqueous suspension containing 3'-azido-3'-deoxythymidine is orally administered.
Claim 23
Independent Claim
36 words
A method of treating a human having acquired immunodeficiency syndrome related complex comprising the parenteral administration of an effective acquired immunodeficiency syndrome related complex treatment amount of 3'-azido-3'-deoxythymidine in a sterile injectable formulation to said human.
Claim 24
Independent Claim
36 words
A method of treating a human having acquired immunodeficiency syndrome related complex comprising the parenteral administration of an effective acquired immunodeficiency syndrome related complex treatment amount of 3'-azido-3'-deoxythymidine in a sterile injectable formulation to said human.
Claim 25
Independent Claim
42 words
A method of treating a human having acquired immunodeficiency syndrome related complex comprising the administration of an effective acquired immunodeficiency syndrome related complex treatment amount of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable alkali metal, alkaline earth or ammonium salt thereof to said human.
Claim 26
Independent Claim
42 words
A method of treating a human having acquired immunodeficiency syndrome related complex comprising the administration of an effective acquired immunodeficiency syndrome related complex treatment amount of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable alkali metal, alkaline earth or ammonium salt thereof to said human.
Claim 27
Dependent Claim
17 words
The method of claim 20 in which 3'-azido-3'-deoxythymidine or the salt thereof is administered orally or parenterally.
Claim 28
Dependent Claim
11 words
The method of claim 21 in which the salt is administered.
Claim 29
Dependent Claim
22 words
The method of claim 20 in which a tablet, capsule or sterile injectable formulation containing 3'-azido-3'-deoxythymidine or said salt thereof is administered.
Claim 30
Dependent Claim
19 words
The method of claim 20 in which an aqueous or non-aqueous solution or suspension containing 3'-azido-3'-deoxythymidine is orally administered.
References Cited (Backward Citations)
WO1979001068A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-02-08 | 1991-08-10 | 1992-02-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-02-08 | 1995-08-10 | 1996-02-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-02-08 | 1999-08-10 | 2000-02-09 | $7700.00 | Window Closed / Lapsed |