US4775659A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Injectable semi-solid formulations
Assignee: Eli Lilly and Co
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Filing: 1985-08-19
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Granted: 1988-10-04
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Expires: 2005-08-19
Abstract
Abstract This invention provides injectable semi-solid formulations comprising a pharmaceutically or veterinary active agent, an oil and a suitable glyceride release modifying agent.
Inventors
- 👤 Arvind L. Thakkar
- 👤 Roger G. Harrison
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 16:46
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019; A61K9/0024; A61K47/00; A61K47/06; A61K47/08; A61K47/14; A61K47/44
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
65 words
An injectable pharmaceutical or veterinary formulation substantially free of fatty acid salts of aluminum comprising from about 0.01% to about 5.0% by weight of a pharmaceutically or verterinary active agent comprised of one or more amino acid fragments, from about 60.0% to about 94.99% by weight of an oil and from about 5.0% to about 35.0% by weight of a suitable glyceride release modifying agent.
Claim 2
Dependent Claim
65 words
An injectable pharmaceutical or veterinary formulation substantially free of fatty acid salts of aluminum comprising from about 0.01% to about 5.0% by weight of a pharmaceutically or verterinary active agent comprised of one or more amino acid fragments, from about 60.0% to about 94.99% by weight of an oil and from about 5.0% to about 35.0% by weight of a suitable glyceride release modifying agent.
Claim 3
Dependent Claim
16 words
A formulation of claim 1 wherein the pharmaceutically or veterinary active agent is methionyl-human growth hormone.
Claim 4
Dependent Claim
19 words
A formulation of claim 2 which has an HLB value in the range of about 1 to about 5.
Claim 5
Dependent Claim
26 words
A formulation of claim 3 wherein the glyceride release modifying agent has a melting point in the range of about 50° C. to about 75° C.
Claim 6
Dependent Claim
28 words
A formulation of claim 1 wherein the suitable glyceride release modifying agent is present at a concentration in the range of about 10.0% to about 25.0% by weight.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-10-04 | 1992-04-04 | 1992-10-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-10-04 | 1996-04-04 | 1996-10-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-10-04 | 2000-04-04 | 2000-10-04 | $7700.00 | Window Closed / Lapsed |