US4780285A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Device for the carrying out of an immunochemical determination
Assignee: Akzo NV
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Filing: 1986-08-05
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Granted: 1988-10-25
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Expires: 2006-08-05
Abstract
Abstract Device for the carrying out of an immunochemical determination comprising at least one holder which is provided with an opening at the top and to the inside of which an immunochemically active substance has been applied. The device is closed at the top by a removable closure means and the holder contains at least a second immunochemically active substance which, in the absence of test medium, in the form in which the second immunochemically active substance is contained in the closed holder, during storage and transport under normal conditions exhibits no interaction with the inside of the holder and is inert with respect to the immunochemically active substance applied thereto. The holder contains a solid, more or less spherical, freeze-dried particle which contains the second immunochemically active substance.
Inventors
- 👤 Leonardus P. C. Kuypers
- 👤 Gerrit Wolters
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 06:10
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/543; G01N33/54366; Y; Y10; Y10S; Y10S436/00; Y10S436/807; Y10S436/809; Y10S436/823
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
136 words
Device for the carrying out of an immunochemical determination comprising at least one sealable container means having an interior cavity capable of containing a liquid sample, said container means having a top portion and a bottom portion with an opening in the top portion thereof, the opening being closed by a removable closure means that permits the introduction of a liquid sample, said container means having a first immunochemically active substance coated onto at least a portion of a surface of the interior cavity, said container means also containing within the interior cavity at least one freeze-dried particle comprising a predetermined amount of at least one additional immunochemically active substance that, in the absence of test medium, has no chemical or physical interaction with said first immunochemically active substance, the container means or the closure means.
Claim 2
Dependent Claim
136 words
Device for the carrying out of an immunochemical determination comprising at least one sealable container means having an interior cavity capable of containing a liquid sample, said container means having a top portion and a bottom portion with an opening in the top portion thereof, the opening being closed by a removable closure means that permits the introduction of a liquid sample, said container means having a first immunochemically active substance coated onto at least a portion of a surface of the interior cavity, said container means also containing within the interior cavity at least one freeze-dried particle comprising a predetermined amount of at least one additional immunochemically active substance that, in the absence of test medium, has no chemical or physical interaction with said first immunochemically active substance, the container means or the closure means.
Claim 3
Dependent Claim
12 words
Device according to claim 1, wherein each freeze-dried particle comprises a stiffener.
Claim 4
Dependent Claim
27 words
Device according to claim 1, wherein the device comprises at least one container means each having only one, substantially spherical, freeze-dried particle in the interior cavity thereof.
Claim 5
Dependent Claim
12 words
Device according to claim 1, wherein each freeze-dried particle comprises buffer material.
Claim 6
Dependent Claim
12 words
Device according to claim 4, wherein each freeze-dried particle comprises a stiffener.
Claim 7
Dependent Claim
12 words
Device according to claim 1, wherein the device comprises 2-1000 container means.
Claim 8
Dependent Claim
23 words
Device according to claim 6, wherein the closure means comprises a plate having protrusions that individually seal the openings in the container means.
Claim 9
Dependent Claim
12 words
Device according to claim 6, wherein the device comprises a microtitre plate.
Claim 10
Dependent Claim
26 words
Device according to claim 8, wherein the closure means comprises a plate having protrusions that individually extend into and seal the openings in the microtitre plate.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-10-25 | 1992-04-25 | 1992-10-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-10-25 | 1996-04-25 | 1996-10-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-10-25 | 2000-04-25 | 2000-10-25 | $7700.00 | Window Closed / Lapsed |