Pharmaceutical product in the form of a pellet with continuous, delayed medicament substance emission

Claim 1

In a pharmaceutical product in the form of a pellet, said product allowing a continuous, delayed, essentially complete emission of a pharmaceutically active agent over a predetermined period of time upon administration to a patient in need thereof, the improvement wherein said pharmaceutical product consists essentially of: (a) a core consisting essentially of a pharmaceutically inert material that dissolves in gastric and intestinal juices, (b) a layer comprising said pharmaceutically active agent and surrounding said core, and (c) an outer pharmaceutically inert coating on said pharmaceutically active agent containing layer, said outer coating conrolling and causing the continuous delayed emission of said pharmaceutically active agent upon administration and, (d) an outer coating containing a pharmaceutically active agent unprotected against the influence of gastric and intestinal juices, and between said core of pharmaceutically inert material dissolving in the gastric and intestinal juices and said layer containing the active agent and surrounding said core, providing a pharmaceutically inert layer which is impermeable to gastric and intestinal juices and which forms a tight seal around said core.