Ophthalmic device comprising a polymer of a telechelic perfluoropolyether

Claim 2

A contact lens comprising a polymer of a telechelic perfluoropolyether monomer having a number average molecular weight between about 500 and 15,000 which has the formula Q--W--C.sub.k F.sub.2k O--.sub.p --C.sub.q F.sub.2q --Z wherein Q is a functional group which will undergo electrophilic, nucleophilic, or free radical reaction; W is a divalent connecting moiety; Z is --WQ or fluorine; p represents the nunber of --C k F 2k O-- subunits in said monomer and is an integer of from 3 to 200; q is an integer of from 1 to 4; and k is the same within a given --C k F 2k O-- subunit but may vary from --C k F 2k O-- subunit to --C k F 2k O-- subunit and is an integer of from 1 to 4.

Claim 3

A contact lens according to claim 1 wherein said perfluoropolyether monomer has the formula Q--W--CF.sub.2 O--CF.sub.2 CF.sub.2 O--.sub.m --CF.sub.2 O--.sub.n CF.sub.2 --Z wherein m and n are numbers providing said number average molecular weight and independently have a value of from 1 to 120; the sum of m and n is from 7 to 120; and the ratio of m/n is from 0.2/1 to 5/1.

Claim 4

A contact lens according to claim 1 wherein said Q group has a group functionality in the range of 1.5 to 2.

Claim 5

A contact lens according to claim 1 wherein said reactive group has a group functionality of 2.

Claim 6

A contact lens according to claim 1 which contains less than 10% by weight of water.

Claim 7

An oxygen permeable contact lens according to claim 1.

Claim 8

A contact lens according to claim 6 which is resistant to absorption of tear components.

Claim 9

A flexible, mechanically strong contact lens according to claim 6.

Claim 10

A contact lens according to claim 6 having an oxygen permeability of at least 10 Barrers.

Claim 11

A contact lens comprising an oxygen permeable copolymer of (a) a telechelic perfluoropolyether monomer having a number average molecular weight between about 500 and 15,000 which has the formula Q--W--C.sub.k F.sub.2k O--.sub.p --C.sub.q F.sub.2q --Z wherein Q is a functional group which will undergo electrophilic, nucleophilic, or free radical reaction; W is a divalent connecting moiety; Z is --WQ or fluorine; p represents the number of --C k F 2k O-- subunits in said monomer and is an integer of from 3 to 200; q is an integer of from 1 to 4; and k is the same within a given --C k F 2k O-- subunit but may vary from --C k F 2k O-- subunit to --C k F 2k O-- subunit and is an integer of from 1 to 4, and (b) a compatible, first comonomer copolymerizable with said telechelic perfluoropolyether monomer.

Claim 12

A contact lens comprising an oxygen permeable copolymer of (a) a telechelic perfluoropolyether monomer having a number average molecular weight between about 500 and 15,000 which has the formula Q--W--C.sub.k F.sub.2k O--.sub.p --C.sub.q F.sub.2q --Z wherein Q is a functional group which will undergo electrophilic, nucleophilic, or free radical reaction; W is a divalent connecting moiety; Z is --WQ or fluorine; p represents the number of --C k F 2k O-- subunits in said monomer and is an integer of from 3 to 200; q is an integer of from 1 to 4; and k is the same within a given --C k F 2k O-- subunit but may vary from --C k F 2k O-- subunit to --C k F 2k O-- subunit and is an integer of from 1 to 4, and (b) a compatible, first comonomer copolymerizable with said telechelic perfluoropolyether monomer.

Claim 13

A contact lens according to claim 10 comprising from 98 to 50 weight percent of said telechelic perfluoropolyether monomer and correspondingly from 2 to 50 weight percent of said first comonomer.

Claim 14

A contact lens according to claim 10 wherein said oxygen permeable copolymer is a copolymer of (a) said telechelic perfluoropolyether monomer, (b) said first comonomer, and (c) a second copolymerizable comonomer containing a hydrophilic group.

Claim 15

A contact lens according to claim 1 wherein Q is an ethylenically unsaturated group, and said first comonomer is an ethylenically unsaturated comonomer.

Claim 16

A contact lens according to claim 12 comprising from 50 to 88 weight percent said telechelic perfluoropolyether, from 10 to 48 weight percent said ethylenically unsaturated first comonomer, and from 2 to 10 weight percent said second copolymerizable comonomer.

Claim 17

A contact lens according to claim 13 wherein said ethylenically unsaturated first comonomer is selected from methyl or ethyl acrylate, methyl or ethyl methacrylate, cyclohexyl methacrylate, methyl 2-chloroacrylate, 2-ethoxyethyl methacrylate, 2,2,2-trifluoroethyl acrylate or methacrylate, 2-cyanoethyl methacrylate, 2-(N-methylcarbamoyloxy)ethyl acrylate or methacrylate, acrylic acid, methacrylic acid, vinylidene chloride, vinylidene fluoride, methacryloyloxypropyl-tris(trimethylsilyl)siloxane, methacryloyloxymethylpentamethyldisiloxane, and mixtures thereof.

Claim 18

A contact lens according to claim 15 wherein said ethylenically unsaturated first comonomer is selected from methyl methacrylate, ethyl methacrylate, or cyclohexyl methacrylate.

Claim 19

A contact lens according to claim 16 wherein said ethylenically unsaturated first comonomer is methyl methacrylate.

Claim 20

A contact lens according to claim 13 wherein said second copolymerizable comonomer is an ethylenically unsaturated monomer and said hydrophilic group is selected from the group consisting of hydroxy groups, carboxy groups, carbonamide groups, sulfonyl groups, and sulfonamide groups.

Claim 21

A contact lens according to claim 18 wherein said second copolymerizable comonomer is selected from the group consisting of 2-hydroxyethyl acrylate or methacrylate, 3-hydroxypropyl acrylate, 4-hydroxybutyl acrylate, 5-hydroxypentyl acrylate, 2,3-dihydroxypropyl acrylate or methacrylate, N-vinyl-2-pyrrolidone, 2-carboxyethyl acrylate, 2-carbonamidoethyl methacrylate, 2-sulfoethyl methacrylate, 2-sulfoamidoethyl acrylate, vinylsulfonic acid, and mixtures thereof.

Claim 22

A contact lens according to claim 18 wherein said second copolymerizable comonomer is selected from 2-hydroxyethyl acrylate and methacrylate, 2,3-dihydroxypropyl acrylate and methacrylate, N-vinyl-2-pyrrolidone, and mixtures thereof.

Claim 23

A contact lens according to claim 20 wherein said second copolymerizable comonomer is N-vinyl-2-pyrrolidone.

Claim 24

A contact lens according to claim 20 wherein said second copolymerizable comonomer is 2-hydroxyethyl methacrylate.

Claim 25

A contact lens according to claim 18 wherein said perfluoropolyether monomer, said ethylenically unsaturated first comonomer, and said second copolymerizable comonomer are further polymerized with a third comonomer selected from the group consisting of ethylene glycol diacrylate, ethyleneglycol dimethacrylate, diethyleneglycol dimethacrylate, allyl methacrylate, trimethylolpropane trimethacrylate, divinyl benzene, diallyl phthalate, tris(2-acryloyloxyethyl)isocyanurate, and 1,3,5-tri(2-methacryloxyethyl)isocyanurate.

Claim 26

A contact lens according to claim 23 wherein Q is selected from the group consisting of vinyl, epoxide, isocyanate, carboxyl, hydroxyl, amino, sulfhydryl, sulfalkyl, silyl, cyano, sulfoalkyl, carbonyloxy, oxycyano, cyanamide, iodo, carbonyl, alkyl ether, sulfonyl chloride, and imino groups.

Claim 27

A contact lens according to claim 24 wherein Q is selected from the group consisting of ##STR27## --NCO, --COOH, --OH, --NH 2 , --SR, --SiR g R 1 , --CN, --OSO 2 CF 3 , --OCOCl, --OCN, --N(R)CN, --I, --CHO, --CH(OR) 2 , --SO 2 Cl, --C(OR)═NH, and --C(NH 2 )═NH wherein R is selected from hydrogen and lower alkyl containing from one to four carbon atoms, R 1 is selected from halogen, --OR, ##STR28## and --CH═CH 2 , and g is 0, 1, 2 or 3.

Claim 28

A contact lens according to claim 25 wherein Q is selected from the group consisting of ##STR29## --NCO, --COOH, --OH, and --NH 2 wherein R is hydrogen or methyl.

Claim 29

A contact lens according to claim 26 wherein said end group is selected from ##STR30## and --NCO.

Claim 30

A contact lens according to claim 27 wherein R is hydrogen.

Claim 31

A contact lens according to claim 27 wherein R is methyl.