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US4820352A Expired / Lapsed US ⏱️ 0.0 years remaining

Cleaning and conditioning solutions for contact lenses and methods of use

Assignee: Bausch and Lomb Inc
•
Filing: 1986-01-22
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Granted: 1989-04-11
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Expires: 2006-01-22
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Abstract

Abstract Contact lens cleaning compositions comprising preserved surfactant-containing solutions of a poly(oxypropylene)-poly(oxyethylene) adduct of ethylene diamine having a molecular weight from about 7500 to as high as 27,000 wherein at least 40 weight percent of the adduct is poly(oxyethylene) hydrophilic units. The solutions are effective in removing protein/lipid tear film deposits on both hard and soft contact lenses while providing a prophylactic-like action in retarding the formation of subsequent tear film deposits. The compositions provide effective cleaning and conditioning action using both ambient and high temperature disinfection methods.

Inventors

  • 👤 Thomas M. Riedhammer
  • 👤 Francis X. Smith

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-01 12:39
CPC Classifications
C; C11; C11D; C11D1/00; C11D1/008; A; A61; A61L; A61L12/00; A61L12/08; A61L12/14; C11D3/00; C11D3/0005; C11D3/0078; C11D3/16; C11D3/37; C11D3/3703; C11D3/3707; C11D3/48; C11D1/38; C11D1/42; C11D1/44

Claims Analysis

Total Claims: 22
Claim 1
Independent Claim 87 words
An aqueous composition for effectively cleaning and conditioning contact lenses at ambient and elevated temperature conditions, consisting essentially of (a) from about 0.01 to about 15 weight percent of a poly(oxypropylene)-poly(oxyethylene) adduct of ethylene diamine having a molecular weight from about 7500 to about 27,000 wherein at least 40 weight percent of said adduct is poly(oxyethylene). (b) a germicidal agent in a sufficient amount of preserve sterility of the composition, and (c) water, said composition being free of amounts of thickening agents which materially alter its viscosity.
Claim 2
Dependent Claim 87 words
An aqueous composition for effectively cleaning and conditioning contact lenses at ambient and elevated temperature conditions, consisting essentially of (a) from about 0.01 to about 15 weight percent of a poly(oxypropylene)-poly(oxyethylene) adduct of ethylene diamine having a molecular weight from about 7500 to about 27,000 wherein at least 40 weight percent of said adduct is poly(oxyethylene). (b) a germicidal agent in a sufficient amount of preserve sterility of the composition, and (c) water, said composition being free of amounts of thickening agents which materially alter its viscosity.
Claim 3
Dependent Claim 33 words
The composition of claim 1 wherein the molecular weight of the adduct is from about 10,000 to about 20,000 and from about 40 to about 80 weight percent of the adduct is poly(oxyethylene).
Claim 4
Dependent Claim 33 words
The composition of claim 2 wherein the molecular weight of the adduct is from about 12,000 to about 19,000 and from about 60 to about 80 weight percent of the adduct is poly(oxyethylene).
Claim 5
Dependent Claim 21 words
The composition of claim 2 wherein the adduct is present in an amount from about 0.1 to about 5 weight percent.
Claim 6
Dependent Claim 9 words
The composition of claim 4, including a tonicity agent.
Claim 7
Dependent Claim 9 words
The composition of claim 5, including a buffering agent.
Claim 8
Dependent Claim 11 words
The composition of claim 6 wherein the germicidal agent is thimerosal.
Claim 9
Dependent Claim 12 words
The composition of claim 6 wherein the germicidal agent is sorbic acid.
Claim 10
Dependent Claim 84 words
An aqueous composition for inhibiting the formation of tear film deposits on contact lenses, consisting essentially of (a) at least 0.01 weight percent of poly(oxypropylene)-poly(oxyethylene) adduct of ethylene diamine having a molecular weight from about 10,000 to about 20,000 wherein at least 40 weight percent of said adduct is poly(oxyethylene), (b) a germicidal agent in a sufficient amount to preserve the sterility of the composition, (c) a tonicity agent, and (d) water, said composition being free of thickening agents which materially alter its viscosity.
Claim 11
Dependent Claim 84 words
An aqueous composition for inhibiting the formation of tear film deposits on contact lenses, consisting essentially of (a) at least 0.01 weight percent of poly(oxypropylene)-poly(oxyethylene) adduct of ethylene diamine having a molecular weight from about 10,000 to about 20,000 wherein at least 40 weight percent of said adduct is poly(oxyethylene), (b) a germicidal agent in a sufficient amount to preserve the sterility of the composition, (c) a tonicity agent, and (d) water, said composition being free of thickening agents which materially alter its viscosity.
Claim 12
Dependent Claim 30 words
The composition of claim 9 wherein the molecular weight of the adduct is from about 12,000 to about 19,000 and at least 60 weight percent of the adduct is poly(oxyethylene).
Claim 13
Dependent Claim 126 words
An aqueous composition for efficient cleaning of tear film build-up and debris from soft contact lenses by cold soaking or heat disinfecting methods, said composition consisting essentially of (a) from about 0.1 to about 5 weight percent of poly(oxypropylene)-poly(oxyethylene) adduct of ethylene diamine having a molecular weight ranging from about 12,000 to about 19,000 wherein at least 60 weight percent of the adduct is poly(oxyethylene), (b) a germicidal agent in a sufficient amount to preserve the sterility of the composition, (c) a sequestering agent, (d) a tonicity agent, (e) a buffering agent in a sufficient amount to maintain the pH of the composition in a range of about 6.5 to 7.8, and (f) water, said composition being free of thickening agents which materially alter its viscosity.
Claim 14
Dependent Claim 126 words
An aqueous composition for efficient cleaning of tear film build-up and debris from soft contact lenses by cold soaking or heat disinfecting methods, said composition consisting essentially of (a) from about 0.1 to about 5 weight percent of poly(oxypropylene)-poly(oxyethylene) adduct of ethylene diamine having a molecular weight ranging from about 12,000 to about 19,000 wherein at least 60 weight percent of the adduct is poly(oxyethylene), (b) a germicidal agent in a sufficient amount to preserve the sterility of the composition, (c) a sequestering agent, (d) a tonicity agent, (e) a buffering agent in a sufficient amount to maintain the pH of the composition in a range of about 6.5 to 7.8, and (f) water, said composition being free of thickening agents which materially alter its viscosity.
Claim 15
Dependent Claim 25 words
The composition of claim 11 wherein the adduct has a molecular weight of approximately 14,500 and about 70 weight percent of the adduct is poly(oxyethylene).
Claim 16
Dependent Claim 44 words
The method of cleaning and conditioning contact lenses which comprises contacting the lenses with the composition of claim 1 for a sufficient time period to remove film build-up and any debris, said cleaning and conditioning being conducted at either ambient or elevated temperature conditions.
Claim 17
Dependent Claim 19 words
The method of claim 13, including the step of rinsing the cleaned and conditioned lenses with a saline solution.
Claim 18
Dependent Claim 26 words
The method of claim 14 wherein cleaning and conditioning of the lenses is carried out at temperatures ranging from about 20° C. to about 90° C.
Claim 19
Dependent Claim 36 words
A method of inhibiting the formation of tear film build-up on soft contact lenses which comprises contacting the lenses with the composition of claim 5, said cleaning being carried out by cold soaking or heat disinfection.
Claim 20
Dependent Claim 21 words
The method of claim 16 wherein the lenses are conditioned by heat disinfection at a temperature of at least 80° C.
Claim 21
Dependent Claim 46 words
A method of cleaning and conditioning soft contact lenses which comprises contacting the lenses with the composition of claim 11 for a sufficient time period to remove film build-up, said cleaning and conditioning being conducted at temperatures ranging from about 20° C. to about 90° C.
Claim 22
Dependent Claim 19 words
The method of claim 18, including the step of rinsing the cleaned and conditioned lenses with a saline solution.

References Cited (Backward Citations)

US3882036A Cited
US3954644A Cited
US3884826A Cited
US4029817A Cited
US4048122A Cited
US4127423A Cited
US4323467A Cited
US4440662A Cited
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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1992-04-10 1992-10-10 1993-04-11 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1996-04-10 1996-10-10 1997-04-11 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2000-04-10 2000-10-10 2001-04-11 $7700.00 Window Closed / Lapsed

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