US4886866A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Contact lenses based on biocompatible polyurethane and polyurea-urethane hydrated polymers
Assignee: Hampshire Chemical Corp
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Filing: 1989-02-16
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Granted: 1989-12-12
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Expires: 2009-02-16
Abstract
Abstract Hydrophilic polymeric soft contact lenses which are characterized by their biocompatibility and resistance to nonspecific protein adsorption. At least 75%, preferably at least 80%, of the prepolymers from which the lenses are prepared are isocyanate-capped oxyethylene-based diols or polyols having molecular weight of about 7000-30,000. Essentially all of the hydroxyl groups of the diols or polyols are capped with polyisocyanate prior to formation of the hydrated polymer of which the contact lenses are made.
Inventors
- 👤 James A. Braatz
- 👤 Clifton L. Kehr
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 10:24
CPC Classifications
C; C08; C08G; C08G18/00; C08G18/06; C08G18/28; C08G18/40; C08G18/48; C08G18/4833; C08G18/4837; C08G18/08; C08G18/10; G; G02; G02B; G02B1/00; G02B1/04; G02B1/041; G02B1/043; C08G2210/00; Y; Y10; Y10S; Y10S528/00; Y10S528/904
Claims Analysis
Total Claims: 21
Claim 1
Independent Claim
60 words
A hydrophilic, biocompatible contact lense comprising a hydrated polyurea-urethane polymer derived from prepolymer units at least 75% of which are oxyethylene-based diols or polyols having molecular weights of about 7000 to about 30,000, said diols or polyols having essentially all of the hydroxyl groups capped with polyisocyanate, said contact lens characterized by a non-ionic surface which resists nonspecific protein adsorption.
Claim 2
Dependent Claim
60 words
A hydrophilic, biocompatible contact lense comprising a hydrated polyurea-urethane polymer derived from prepolymer units at least 75% of which are oxyethylene-based diols or polyols having molecular weights of about 7000 to about 30,000, said diols or polyols having essentially all of the hydroxyl groups capped with polyisocyanate, said contact lens characterized by a non-ionic surface which resists nonspecific protein adsorption.
Claim 3
Dependent Claim
21 words
The contact lens of claim 1 in which at least 90% of said prepolymer units are polyisocyanatecapped oxyethylene-based diols or polyols.
Claim 4
Dependent Claim
20 words
The contact lens of claim 1 in which substantially all of said prepolymer units are polyisocyanate-capped oxyethylene-based diols or polyols.
Claim 5
Dependent Claim
20 words
The contact lens of claim 1 in which said diols or polyols are capped with an aliphatic or cycloaliphatic polyisocyanate.
Claim 6
Dependent Claim
13 words
The contact lens of claim 4 in which said polyisocyanate is isophorone diisocyanate.
Claim 7
Dependent Claim
32 words
The contact lens of claim 1 in which the diols or polyols are capped with polyisocyanate in such a manner that the isocyanate-to-hydroxyl group ratio is between about 1.8 and about 2.2.
Claim 8
Dependent Claim
32 words
The contact lens of claim 1 in which said prepolymer units are prepared from a 7000 molecular weight triol copolymer of ethylene oxide (75%) and propylene oxide (25%), capped with isophorone diisocyanate.
Claim 9
Dependent Claim
29 words
The contact lens of claim 1 in which said prepolymer units are prepared from a 10,000 molecular weight triol prepared from 100% homopolymeric ethylene oxide, capped with isophorone diisocyanate.
Claim 10
Dependent Claim
12 words
The contact lens of claim 1 which contains comprises an antioxidation agent.
Claim 11
Dependent Claim
19 words
The contact lens of claim 1 which an ultraviolet radiation stabilizer, optical brightener, preservative, colorant or strength reinforcing agent.
Claim 12
Dependent Claim
11 words
The contact lens of claim 1 which is soft and flexible.
Claim 13
Dependent Claim
9 words
The contact lens of claim 1 which is resilient.
Claim 14
Dependent Claim
11 words
The contact lens of claim 1 which exhibits good strength characteristics.
Claim 15
Dependent Claim
9 words
The contact lens of claim 1 which is transparent.
Claim 16
Dependent Claim
14 words
The contact lens of claim 14 which remains transparent after heating to 100° C.
Claim 17
Dependent Claim
18 words
The contact lens of claim 15 which remains transparent after heating in the presence of water or steam.
Claim 18
Dependent Claim
21 words
The contact lens of claim 1 which is capable of transporting oxygen sufficiently to meet the requirements of the human cornea.
Claim 19
Dependent Claim
17 words
The contact lens of claim 17 which has an oxygen permeability similar to that of pure water.
Claim 20
Dependent Claim
76 words
An improved hydrophilic, biocompatible contact lens the surface of which resists nonspecific protein adsorption, said contact lens consisting of a contact lens coated with a non-ionic and polyurea-urethane polymer coating, said polymer coating formed by the polymerization of a prepolymer, at least 75% of the units of which are oxyethylene-based diols or polyols having molecular weights of about 7000 to about 30,000, said diols or polyols having essentially all of the hydroxyl groups capped with polyisocyanate.
Claim 21
Dependent Claim
76 words
An improved hydrophilic, biocompatible contact lens the surface of which resists nonspecific protein adsorption, said contact lens consisting of a contact lens coated with a non-ionic and polyurea-urethane polymer coating, said polymer coating formed by the polymerization of a prepolymer, at least 75% of the units of which are oxyethylene-based diols or polyols having molecular weights of about 7000 to about 30,000, said diols or polyols having essentially all of the hydroxyl groups capped with polyisocyanate.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-12-11 | 1993-06-12 | 1993-12-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-12-11 | 1997-06-12 | 1997-12-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-12-11 | 2001-06-12 | 2001-12-12 | $7700.00 | Window Closed / Lapsed |