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US4904257A Expired / Lapsed US ⏱️ 0.0 years remaining

Fibrous bone filler and process of producing the same

Assignee: Pentax Corp
•
Filing: 1988-07-06
•
Granted: 1990-02-27
•
Expires: 2008-07-06
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Abstract

Abstract A fibrous bone filler having an excellent biocompatibility. The bone filler comprises fibers containing hydroxyl apatite. The hydroxyl apatite is "intact", that is, the hydroxyl apatite substantially retains its hydroxyl groups.

Inventors

  • 👤 Shoichi Mori
  • 👤 Shigeo Fujii
  • 👤 Masao Yoshizawa
  • 👤 Kenji Miyasaka
  • 👤 Jyoichi Tabuchi
  • 👤 Kazufumi Egawa
  • 👤 Minoru Hirano
  • 👤 Yoshikazu Yoshida

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-04 11:07
CPC Classifications
D; D01; D01F; D01F9/00; D01F9/08; A; A61; A61F; A61F2/00; A61F2/02; A61F2/28; A61L; A61L27/00; A61L27/02; A61L27/12; A61L27/40; A61L27/44; A61L27/46; A61F2310/00; A61F2310/00005; A61F2310/00179; A61F2310/00293; A61L2430/00; A61L2430/02; Y; Y10; Y10T; Y10T428/00; Y10T428/249921

Claims Analysis

Total Claims: 21
Claim 1
Independent Claim 87 words
A method of filling a void in a bond which comprises filling the void with a fibrous bone filler comprising fibers containing intact hydroxyl apatite formed by solution spinning an aqueous suspension comprised of 5 to 70 percent by weight of hydroxyl apatite, 5 to 40 percent by weight of a water-soluble binder and 10 to 90 percent by weight of water, wherein said fibrous bone filler is immersed in an immersion liquid selected from the group consisting of water, physiological saline, chondroitin solution, and hyaluronic solution.
Claim 2
Independent Claim 87 words
A method of filling a void in a bond which comprises filling the void with a fibrous bone filler comprising fibers containing intact hydroxyl apatite formed by solution spinning an aqueous suspension comprised of 5 to 70 percent by weight of hydroxyl apatite, 5 to 40 percent by weight of a water-soluble binder and 10 to 90 percent by weight of water, wherein said fibrous bone filler is immersed in an immersion liquid selected from the group consisting of water, physiological saline, chondroitin solution, and hyaluronic solution.
Claim 3
Dependent Claim 20 words
The method of claim 1, wherein the content of the intact hydroxyl apatite in the fiber is at least 25%.
Claim 4
Dependent Claim 20 words
The method of claim 2, wherein the content of the intact hydroxyl apatite in the fiber is at least 50%.
Claim 5
Dependent Claim 14 words
The method of claim 3, wherein the fiber essentially consists of intact hydroxyl apatite.
Claim 6
Dependent Claim 22 words
The method of claim 1, wherein the bone filler is in the form of a non-woven fabric, cotton, absorbent cotton, or roving.
Claim 7
Dependent Claim 12 words
The method of claim 1, wherein the fiber contains a reinforcing material.
Claim 8
Dependent Claim 15 words
The method of claim 6, wherein the reinforcing material is Ca 3 PO 4 .
Claim 9
Dependent Claim 17 words
The method of claim 1, wherein the diameter of the fiber is about 1 to 30 μm.
Claim 10
Dependent Claim 17 words
The method of claim 8, wherein the diameter of the fiber is about 1 to 30 μm.
Claim 11
Dependent Claim 25 words
The method of claim 1, wherein said immersion liquid is in an amount of from 1 to 20% by weight of said fibrous bone filler.
Claim 12
Dependent Claim 25 words
The method of claim 1, wherein said immersion liquid is in an amount of from 5 to 10% by weight of said fibrous bone filler.
Claim 13
Dependent Claim 51 words
The method of claim 1, wherein said immersion liquid is selected from the group consisting of chondroitin solution and hyaluronic solution, and wherein said immersion liquid is a solution with water as a solvent and with a solute concentration of about from 1 to 20% by weight of said immersion liquid.
Claim 14
Dependent Claim 51 words
The method of claim 11, wherein said immersion liquid is selected from the group consisting of chondroitin solution and hyaluronic solution, and wherein said immersion liquid is a solution with water as a solvent and with a solute concentration of about from 1 to 20% by weight of said immersion liquid.
Claim 15
Dependent Claim 25 words
The method of claim 4, wherein said immersion liquid is in an amount of from 1 to 20% by weight of said fibrous bone filler.
Claim 16
Dependent Claim 25 words
The method of claim 7, wherein said immersion liquid is in an amount of from 1 to 20% by weight of said fibrous bone filler.
Claim 17
Dependent Claim 25 words
The method of claim 9, wherein said immersion liquid is in an amount of from 1 to 20% by weight of said fibrous bone filler.
Claim 18
Dependent Claim 26 words
The method of claim 1, wherein said water-soluble binder is selected from the group consisting of polyvinyl alcohol, carboxymethyl cellulose, hydroxylpropyl cellulose, collagen, pullulan and chitin.
Claim 19
Dependent Claim 11 words
The method of claim 17, wherein said water-soluble binder is pullulan.
Claim 20
Dependent Claim 40 words
The method of claim 1, wherein said aqueous suspension is comprised of 15 to 20 percent by weight of hydroxyl apatite, 20 to 25 percent by weight of a water-soluble binder and 60 to 65 percent by weight of water.
Claim 21
Dependent Claim 40 words
The method of claim 1, wherein said aqueous suspension is comprised of 15 to 30 percent by weight of hydroxyl apatite, 15 to 30 percent by weight of a water-soluble binder and 50 to 70 percent by weight of water.

References Cited (Backward Citations)

US4172128A Cited
US4097935A Cited
US4330514A Cited
US4603050A Cited
EP0104640A2 Cited
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US4655777A Cited
EP0174827A2 Cited
US4659617A Cited
US4776890A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1993-02-26 1993-08-28 1994-02-27 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1997-02-26 1997-08-28 1998-02-27 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2001-02-26 2001-08-28 2002-02-27 $7700.00 Window Closed / Lapsed

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