US4911927A
Expired / Lapsed
US
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Method and apparatus for adding chemotherapeutic agents to dental floss
Assignee: WhiteHill Oral Technologies Inc
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Filing: 1988-11-14
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Granted: 1990-03-27
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Expires: 2008-11-14
Abstract
Abstract A method and apparatus for the manufacture of various dental flosses containing chemotherapeutic preparations which are releasable during flossing.
Inventors
- 👤 Ira D. Hill
- 👤 Robert D. White
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 20:16
CPC Classifications
A; A61; A61Q; A61Q11/00; A61C; A61C15/00; A61C15/04; A61C15/041; A61K; A61K8/00; A61K8/02; A61K9/00; A61K9/70
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
198 words
A method of adding a chemotherapeutic preparation to a multi fiber dental floss wherein: the preparation comprises: a. a surfactant selected from the group consisting of: sodium lauryl sulfate, sodium lauroyl sarcosinate, polyethylene glycol stearate, polyethylene glycol monostearate, coconut monoglyceride sulfonates, sodium alkyl sulfates, sodium alkyl sulfoacetates, block copolymers of polyoxyethylene and polyoxybutylene, allylpolyglycol ether carboxylates, polyethylene derivatives of sorbitan esters, propoxylated cetyl alcohol, block copolymers comprising a cogeneric mixture of conjugated polyoxybutylene and polyoxylethylene compounds having as a hydrophobe a polyoxybutylene polymer of at least 1200 molecular weight, soap powder, and mixtures thereof, and b. a coating substance insoluble in said surfactant selected from the group consisting of: silicones, silicone glycol co-polymers, polydimethyl siloxanes, long chain hydrocarbons, normal paraffins having a chain length of 16 carbon atoms or greater, paraffins with several loci of branching and unsaturation and carbowaxes, and the method comprises, repetitively: a. spreading said floss fibers, b. introducing said preparations in a molten state into the spaces around said fibers, and c. returning said fibers to their preload twist, such that from between about 10 and about 80 mg of said preparation are contained in one yard of said floss in a releasable state.
Claim 2
Independent Claim
198 words
A method of adding a chemotherapeutic preparation to a multi fiber dental floss wherein: the preparation comprises: a. a surfactant selected from the group consisting of: sodium lauryl sulfate, sodium lauroyl sarcosinate, polyethylene glycol stearate, polyethylene glycol monostearate, coconut monoglyceride sulfonates, sodium alkyl sulfates, sodium alkyl sulfoacetates, block copolymers of polyoxyethylene and polyoxybutylene, allylpolyglycol ether carboxylates, polyethylene derivatives of sorbitan esters, propoxylated cetyl alcohol, block copolymers comprising a cogeneric mixture of conjugated polyoxybutylene and polyoxylethylene compounds having as a hydrophobe a polyoxybutylene polymer of at least 1200 molecular weight, soap powder, and mixtures thereof, and b. a coating substance insoluble in said surfactant selected from the group consisting of: silicones, silicone glycol co-polymers, polydimethyl siloxanes, long chain hydrocarbons, normal paraffins having a chain length of 16 carbon atoms or greater, paraffins with several loci of branching and unsaturation and carbowaxes, and the method comprises, repetitively: a. spreading said floss fibers, b. introducing said preparations in a molten state into the spaces around said fibers, and c. returning said fibers to their preload twist, such that from between about 10 and about 80 mg of said preparation are contained in one yard of said floss in a releasable state.
Claim 3
Dependent Claim
33 words
A method of adding a chemotherapeutic preparation to dental floss according to claim 1 wherein said preparation is loaded into the floss at a rate between about 10 mg/yd and about 100 mg/yd.
Claim 4
Dependent Claim
35 words
A method of adding a chemotherapeutic preparation to dental floss according to claim 1 wherein said preparation is released during flossing at a rate between about 10% and about 80% by weight of said load.
Claim 5
Dependent Claim
30 words
A method of adding a chemotherapeutic preparation to dental floss according to claim 1 wherein said floss is multi fiber, multifilament with a denier between about 300 and about 1200.
Claim 6
Dependent Claim
24 words
A method of adding a chemotherapeutic preparation to floss according to claim 1 wherein the floss contains between about 100 and about 800 filaments.
Claim 7
Dependent Claim
47 words
A method of adding a chemotherapeutic preparation to floss according to claim 1 wherein said preparation is insoluble in said floss and contained in the interstitial spaces between the fibers of said floss such that up to 80% by weight is released from said floss during flossing.
Claim 8
Dependent Claim
50 words
A method of adding a chemotherapeutic preparation to floss according to claim 1 wherein said preparation is loaded into the floss at a rate between about 20 and about 50 mg/yd and wherein said preparation releases at a rate between about 30% and about 70% by weight of the load.
Claim 9
Dependent Claim
26 words
A method according to claim 1 wherein the preparation contains an antimicrobial selected from the goup consisting of stannous fluoride, chlorhexidine, organo-iodine salts and mixtures thereof.
Claim 10
Dependent Claim
25 words
A method according to claim 1 wherein spreading of the fibers is achieved by passing the floss over a series of flat surfaces under tension.
Claim 11
Dependent Claim
18 words
A method according to claim 1 wherein said spreading of the fibers is achieved by compressing the floss.
Claim 12
Dependent Claim
31 words
A method according to claim 10 wherein the compressing is achieved with nip rollers and the preparation is forced between the fibers by the hydraulyic pressure generated by said nip rollers.
Claim 13
Dependent Claim
32 words
A method according to claim 1 wherein the fibers are spread by a ladder guide means, preheated, and the preparation to be added is heated and forced under pressure between said fibers.
Claim 14
Dependent Claim
24 words
A method according to claim 1 wherein the preparation is introduced into the spread floss fibers by means of a heated tip applicator means.
Claim 15
Dependent Claim
27 words
A method according to claim 1 wherein the preparation is introduced into the spread floss fibers by means of a heated pump applicator and ceramic chamber means.
Claim 16
Dependent Claim
24 words
A method according to claim 14 wherein the pump applicator is provided with vortex mixing means to accommodate the addition of heat sensitive antimicrobials.
Claim 17
Dependent Claim
38 words
A method according to claim 1 wherein the floss containing the chemotherapeutic preparation is passed through a powder charging means at a rate sufficient to load between about 0.8 and about 9.0 mg/yd of powder onto the floss.
Claim 18
Dependent Claim
19 words
A method according to claim 1 wherein the addition of the chemotherapeutic preparation is performed under substantially water-free conditions.
References Cited (Backward Citations)
US4029113A
Cited
US4610872A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 1993-03-26 | 1993-09-25 | 1994-03-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-03-26 | 1997-09-25 | 1998-03-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-03-26 | 2001-09-25 | 2002-03-27 | $7700.00 | Window Closed / Lapsed |