US4916078A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for carrying out analytical determinations and means for carrying out this process
Assignee: Roche Diagnostics GmbH
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Filing: 1987-09-03
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Granted: 1990-04-10
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Expires: 2007-09-03
Abstract
Abstract The present invention provides a process for carrying out an analytical determination by mixing and incubating a sample solution with at least one reagent and measuring a parameter in the reaction mixture, the sample solution being transported from an application point to a measurement point, wherein a sample solution is first transported to a soluble dry reagent, with at least partial dissolving of the latter, and then further transported to a measurement point, the transport taking place by two different forces, whereby, at least on a part of the transport path, it is brought about by a surface force acting on the solution as a first force, which, for the regulation of the transport velocity or transport direction, is superimposed by a centrifugal force and/or pressure force as a second force which, depending upon which transport state of the fluid is to be adjusted, is made greater or smaller than the first force.
Inventors
- 👤 Sigmar Klose
- 👤 Fritz Stahler
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 10:16
CPC Classifications
B; B01; B01L; B01L3/00; B01L3/50; B01L3/502; B01L3/5027; B04; B04B; B04B5/00; B04B5/04; B04B5/0407; C; C12; C12Q; C12Q1/00; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/5302; B01L2200/00; B01L2200/16; B01L2300/00; B01L2300/08; B01L2300/0809; B01L2300/0861; B01L2300/087; B01L2400/00; B01L2400/04; B01L2400/0403; B01L2400/0406; B01L2400/0409; B01L2400/0475; B01L2400/0481; B01L2400/06; B01L2400/0633; B01L2400/0655; B01L3/502738; Y; Y10; Y10T; Y10T436/00; Y10T436/11; Y10T436/111666
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
187 words
Process for analyzing a fluid sample, comprising: (a) applying a fluid sample to an application point on a transport path, (b) transporting said fluid sample on said path to a reagent containing zone which contains at least one dry reagent which is dissolvable in said fluid sample, (c) mixing and incubating said fluid sample and said dry reagent to form a reaction mixture, and (d) transporting said reaction mixture to a sample measurement point on said transport path to measure a parameter of said reaction mixture, wherein transport of said fluid sample and said reaction mixture on said transport path is accomplished by two transport forces, the first of said forces being a surface force characteristic of said transport path, said first force being a driving force for said fluid sample and said reaction mixture, and the second of said forces being exerted in a direction perpendicular to the transport direction and a controllably variable pressure force which, when superimposed homogeneously on said first force modifies it throughout and, accelerates, impedes, or stops transport flow of said fluid sample or said reaction mixture on said transport path.
Claim 2
Dependent Claim
187 words
Process for analyzing a fluid sample, comprising: (a) applying a fluid sample to an application point on a transport path, (b) transporting said fluid sample on said path to a reagent containing zone which contains at least one dry reagent which is dissolvable in said fluid sample, (c) mixing and incubating said fluid sample and said dry reagent to form a reaction mixture, and (d) transporting said reaction mixture to a sample measurement point on said transport path to measure a parameter of said reaction mixture, wherein transport of said fluid sample and said reaction mixture on said transport path is accomplished by two transport forces, the first of said forces being a surface force characteristic of said transport path, said first force being a driving force for said fluid sample and said reaction mixture, and the second of said forces being exerted in a direction perpendicular to the transport direction and a controllably variable pressure force which, when superimposed homogeneously on said first force modifies it throughout and, accelerates, impedes, or stops transport flow of said fluid sample or said reaction mixture on said transport path.
Claim 3
Dependent Claim
11 words
Process of claim 1, wherein said forces act in different directions.
Claim 4
Dependent Claim
14 words
Process of claim 1, wherein said controllably variable pressure force accelerates said transport flow.
Claim 5
Dependent Claim
14 words
Process of claim 1, wherein said controllably variable pressure force impedes said transport flow.
Claim 6
Dependent Claim
14 words
Process of claim 1, wherein said controllably variable pressure force stops said transport flow.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-04-09 | 1993-10-09 | 1994-04-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-04-09 | 1997-10-09 | 1998-04-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-04-09 | 2001-10-09 | 2002-04-10 | $7700.00 | Window Closed / Lapsed |