Crosslinked siloxane-urethane polymer contact lens

Claim 2

A crosslinked siloxane-urethane polymer in form of an ophthalmic device, which consists essentially of the reaction product of: (A) a di- or poly-hydroxyalkyl substituted alkyl polysiloxane having a number average molecular weight between about 200 and about 10,000, and (B) an aliphatic, cycloaliphatic or aromatic di- or tri-isocyanate; wherein the total number of hydroxyl groups in component (A) is stoichiometrically equivalent to the total number of isocyanate groups in component (B), and with the proviso that an effective crosslinking amount of (A) or (B) or both (A) and (B) is present and possesses a functionality greater than two.

Claim 3

As ophthalmic device according to claim 1 which is a contact lens.

Claim 4

A siloxane-urethane polymer in form of an ophthalmic device according to claim 1 wherein component (A) is a di- or poly-hydroxy substituted polysiloxane of formula A 1 , A 2 or A 3 or mixture thereof, with the structures: ##STR5## wherein: R 1 is an alkyl group of 1 to 4 carbon atoms or phenyl, R 2 is a linear or branched alkylene group with 2 to 6 carbon atoms or a polyoxyalkylene group of structure: ##STR6## wherein R 3 is hydrogen or methyl and n is an integer from 1 to 50; x 1 , x 2 are integers from 1 to 500, y 1 is 0 to 4, y 2 is 2 to 5 with the proviso that the ratios of: ##EQU3## are not greater than 70.

Claim 5

A siloxane-urethane polymer in form of an ophthalmic device according to claim 1 wherein component (B) is a diisocyanate, triisocyanate or mixture thereof selected from the group consisting of ethylene diisocyanate, 1,2-diisocyanatopropane, 1,3-diisocyanato-propane, 1,6-diisocyanatohexane, 1,2-diisocyanatocyclohexane, 1,3-diisocyanato-cyclohexane, 1,4-diisocyanato-benzene; bis(4-isocyanatocyclohexyl)-methane, bis(4-isocyanatocyclohexenyl)-methane, bis(4-isocyanatophenyl)-methane, 1,2-and 1,4-toluene diisocyanate; 3,3-dichloro-4,4'-diisocyanatobiphenyl; tris(4-isocyanalophenyl)methane,1,5-diisocyanato-naphthalene, hydrogenated toluene diisocyanate; 1-isocyanato-methyl-5-isocyanato-1,3-3-trimethylcyclohexane (=isophorone diisocyanate); 1,3,5-tris(6-isocyanatohexyl)biuret, 1,6-diisocyanato-2,2-4-(2,4,4)-trimethyl-hexane, 2,2'-diisocyanatodiethyl fumarate, 1,5-diisocyanato-1-carboxypentane; 1,2-, 1,3-, 1,6-, 1,7-, 1,8-, 2,7- and 2,3-diisocyanatonaphthalene; 2,4- and 2,7-diisocyanato-1-methylnaphthalene; 1,4-diisocyanato-methylcyclo-hexane; 1,3-diisocyanato-6(7)-methylnaphthalene; 4,4'-diisocyanatobiphenyl; 4,4'-diisocyanato-3,3'-dimethoxy-bisphenyl; 3,3'- and 4,4'-diisocyanato-2,2'-dimethyl biphenyl; bis-(4-isocyanatophenyl)ethane and bis(4-isocyanato-phenyl)ether.

Claim 6

A crosslinked siloxane-urethane polymer in the form of an ophthalmic device according to claim 3, wherein (A) contains 40-60 hydroxyl equivalent percent of polysiloxane tetrols A 3 , wherein x 1 is 10-50 and R 1 is methyl, and 40-60 hydroxyl equivalent percent A 1 , where y 1 is zero, x 1 is 15-60, R 1 is methyl, R 2 is propylene, 1-methylpropylene, or ##STR7## (B) is isophorone diisocyanate or 2,2,4(2,4,4)-trimethylhexane-1,6-diisocyanate.

Claim 7

A crosslinked siloxane-urethane polymer in form of an ophthalmic device according to claim 3, (A) is of structure A 1 , where y 1 is zero, x 1 is 5-50, R 1 is methyl, R 2 is propylene, butylene, 1-methylpropylene or ##STR8## the diisocyanate (B) is isophorone diisocyanate or 2,2,4(2,4,4) trimethylhexane-1,6-diisocyanate.

Claim 8

A crosslinked siloxane-urethane polymer in form of an opthalmic device according to claim 3, wherein (A) contains 40-60 hydroxyl equivalent percent of polysiloxane diols of structure A 1 , where y 1 is zero or 1, x 1 is 1-5, R 1 is methyl, R 2 is propylene or butylene, and 60-40 hydroxyl equivalent percent of polysiloxane-tetrols of structure x 1 is 10-50, and R 1 is methyl, and the diisocyanate (B) is isophorone diisocyanate or 2,2,4(2,4,4)-trimethylhexane-1,6-diisocyanate.

Claim 9

A crosslinked siloxane-urethane polymer in the form of an ophthalmic device according to claim 4, wherein (B) is isophorone diisocyanate, 2,2,4(2,4,4)-trimethylhexane-1,6-diisocyanate or 1,2- or 1,4- toluene diisocyanate.