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US5093349A Expired / Lapsed US ⏱️ 0.0 years remaining

Photosensitizing agents

Assignee: Health Research Inc
•
Filing: 1990-10-15
•
Granted: 1992-03-03
•
Expires: 2010-10-15
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Abstract

Abstract New classes of photosensitizing compounds useful in photodynamic therapy are disclosed. These compounds are simplified dimers and polymers of monohydroxy deuteroporphyrins, hydrophobic ethers of these monomers, and red light-absorbing derivatives of methyl pheophorbide-a.

Inventors

  • 👤 Ravindra K. Pandey
  • 👤 Thomas J. Dougherty

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-01 13:11
CPC Classifications
C; C07; C07D; C07D487/00; C07D487/22; A; A61; A61K; A61K41/00; A61K41/0057; A61K41/0071; C07D519/00

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 31 words
A compound of the formula ##STR8## wherein R 1 is H or alkyl and R3 is a hydrophobic group which is saturated or unsaturated, straight or branched chain hydrocarbon or 6-25C.
Claim 2
Dependent Claim 31 words
A compound of the formula ##STR8## wherein R 1 is H or alkyl and R3 is a hydrophobic group which is saturated or unsaturated, straight or branched chain hydrocarbon or 6-25C.
Claim 3
Dependent Claim 12 words
The compound as claimed in claim 1, wherein R 3 is hexyl.
Claim 4
Dependent Claim 35 words
A method to effect the destruction of target virus, cells or tissue, which comprises contacting said target with an effective amount of compound of claim 1, followed by irradiation with light absorbed by said compound.
Claim 5
Dependent Claim 36 words
A method to effect the destruction of target virus, cells or tissue, which comprises contacting said target with an effective amount of the compound of claim 2, followed by irradiation with light absorbed by said compound.
Claim 6
Dependent Claim 31 words
A pharmaceutical composition useful in treatment of a target virus, cells or tissue, which comprises an effective amount of the compound of claim 1 in admixture with a pharmaceutically acceptable excipient.
Claim 7
Dependent Claim 37 words
A pharmaceutical composition useful in treatment of a target virus, cells or tissue, which comprises: an effective amount of the compound of claim 2; and a pharmaceutically acceptable excipient material mixed with the compound of claim 2.

References Cited (Backward Citations)

US4849207A Cited
US4877872A Cited
JPS63101384A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1995-03-03 1995-09-02 1996-03-03 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1999-03-03 1999-09-02 2000-03-03 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2003-03-03 2003-09-02 2004-03-03 $7700.00 Window Closed / Lapsed

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