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US5096836A Expired / Lapsed US ⏱️ 0.0 years remaining

Diagnostic test carrier

Assignee: Roche Diagnostics GmbH
•
Filing: 1990-09-19
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Granted: 1992-03-17
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Expires: 2010-09-19
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Abstract

Abstract At least two layers are fixed together at a distance so that a gap is present between them, wherein the layers are connected with one another by a plurality of discrete melt adhesive regions, intermediate spaces being present between the melt adhesive regions so that a liquid transport in the gap between the layers is assured through the intermediate spaces. To produce this test carrier, the melt adhesive in the form of discrete regions, between which intermediate spaces are present, is applied to a first layer material in a thickness which is greater than the desired gap and a second layer material is pressed against the melt adhesive regions while the melt adhesive is still sufficiently hot in order to be bindable in such a manner that it binds with the melt adhesive but a gap remains between the layer materials.

Inventors

  • 👤 Heinz K. Macho
  • 👤 Klaus D. Hungenberg
  • 👤 Norbert Becker

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-08 20:26
CPC Classifications
B; B01; B01L; B01L3/00; B01L3/50; B01L3/502; B01L3/5027; B01L3/502707; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/52; G01N33/525; B01L2300/00; B01L2300/08; B01L2300/0809; B01L2300/0825; B01L2300/0887; B01L2400/00; B01L2400/04; B01L2400/0403; B01L2400/0406

Claims Analysis

Total Claims: 10
Claim 1
Independent Claim 217 words
A test carrier for determining analyte in a fluid sample, said test carrier comprising a sample application zone comprising a first layer and a second layer and a gap between said first and second layers, said first and second layers being non-absorbent, an evaluation zone comprising a first layer and a second layer and a gap between said first and second layer, at least one of said layers being non-absorbent, said first and second layers in both of said zones being connected together by a plurality of discrete melt adhesive means having a thickness, said adhesive means positioned between said first and second layers so as to provide a plurality of intermediate spaces between said first and second layers, said intermediate spaces having a vertical dimension defining said gap separating said first and second layers, said vertical dimension being defined by the thickness of the melt adhesive means, said gap being dimensioned to assure a capillary action so that said fluid sample can spread out parallel to said first and second layers in a liquid transport path, said liquid transport path formed by said first and second layers in said sample application and said first and second layers in said evaluation zone, said transport path being parallel to said layers and extending through both of said zones.
Claim 2
Dependent Claim 217 words
A test carrier for determining analyte in a fluid sample, said test carrier comprising a sample application zone comprising a first layer and a second layer and a gap between said first and second layers, said first and second layers being non-absorbent, an evaluation zone comprising a first layer and a second layer and a gap between said first and second layer, at least one of said layers being non-absorbent, said first and second layers in both of said zones being connected together by a plurality of discrete melt adhesive means having a thickness, said adhesive means positioned between said first and second layers so as to provide a plurality of intermediate spaces between said first and second layers, said intermediate spaces having a vertical dimension defining said gap separating said first and second layers, said vertical dimension being defined by the thickness of the melt adhesive means, said gap being dimensioned to assure a capillary action so that said fluid sample can spread out parallel to said first and second layers in a liquid transport path, said liquid transport path formed by said first and second layers in said sample application and said first and second layers in said evaluation zone, said transport path being parallel to said layers and extending through both of said zones.
Claim 3
Dependent Claim 19 words
The test carrier of claim 1, wherein said adhesive means have a thickness of from 0.02 to 1.0 mm.
Claim 4
Dependent Claim 19 words
The test carrier of claim 1, wherein said adhesive means have a thickness of from 0.02 to 0.3 mm.
Claim 5
Dependent Claim 13 words
The test carrier of claim 1, wherein said adhesive means are adhesive particles.
Claim 6
Dependent Claim 22 words
The test carrier of claim 1, wherein said particles have an average surface area of from 0.03 to 5.0 mm 2 .
Claim 7
Dependent Claim 29 words
The test carrier of claim 1, wherein said adhesive means comprise a total surface area of for 10 to 70% of the surface area of the layers connected thereby.
Claim 8
Dependent Claim 29 words
The test carrier of claim 1, wherein said adhesive means comprise a total surface area of from 15 to 50% of the surface area of the layers connected thereby.
Claim 9
Dependent Claim 51 words
Method for determining an analyte in a liquid sample comprising contacting said sample to a device of claim 1, wherein at least one of said layers contains a reagent means which produces a detectable signal in the presence of said analyte, and detecting said signal as an indication of said analyte.
Claim 10
Dependent Claim 11 words
Method of claim 8, wherein said liquid sample is whole blood.

References Cited (Backward Citations)

US4582684A Cited
EP0166365A2 Cited
EP0287883A1 Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1995-03-17 1995-09-16 1996-03-17 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1999-03-17 1999-09-16 2000-03-17 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2003-03-17 2003-09-16 2004-03-17 $7700.00 Window Closed / Lapsed

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