US5128136A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Wound healing kit comprised of gelable collagen
Assignee: Oregon Health & Science University
•
Filing: 1991-11-04
•
Granted: 1992-07-07
•
Expires: 2011-11-04
Abstract
Abstract A stabilized collagen gel is disclosed as are methods of making this collagen gel which is useful as a wound dressing to prevent dehydration of the subject being treated and infection of the wound. The collagen gel of the invention is stabilized by combining collagen (preferably in pharmaceutical grade collagen, which is atelopeptide collagen), with iodine or a composition capable of generating iodine. The collagen is flowable on first mixing and undergoes a phase transition to form a stable gel with sufficient structural integrity to form a wound dressing.
Inventors
- 👤 J. Peter Bentley
- 👤 Jack H. Fellman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 16:02
CPC Classifications
A; A61; A61L; A61L26/00; A61L26/0061; A61L26/0066; A01; A01N; A01N59/00; A01N59/12; A61K; A61K33/00; A61K33/18; A61L26/0009; A61L26/0028; A61L26/0033; A61L2300/00; A61L2300/10; A61L2300/106; A61L2300/40; A61L2300/404
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
44 words
A wound healing kit, comprising a first container having therein a composition comprised of water soluble, lyophilized, atelopeptide collagen; and a second container having therein a composition capable of generating iodine in the presence of water in an amount sufficient to gel the collagen.
Claim 2
Dependent Claim
44 words
A wound healing kit, comprising a first container having therein a composition comprised of water soluble, lyophilized, atelopeptide collagen; and a second container having therein a composition capable of generating iodine in the presence of water in an amount sufficient to gel the collagen.
Claim 3
Dependent Claim
28 words
The wound healing kit as claimed in claim 1, wherein the composition capable of generating iodine is comprised of oxidized iodine, a reducing agent and a pH buffer.
Claim 4
Dependent Claim
25 words
The wound healing kit as claimed in claim 2, wherein the oxidized iodine is selected from the group consisting of potassium iodate and iodine pentoxide.
Claim 5
Dependent Claim
30 words
The wound healing kit as claimed in claim 1, wherein the composition capable of generating iodine is comprised of an alkali metal iodide, an oxidizing agent and a pH buffer.
Claim 6
Dependent Claim
42 words
The wound healing kit as claimed in claim 4, wherein the oxidizing agent is selected from the group consisting of persulfate, perborate, citric acid, hydrogen peroxide, tertiary butyl peroxide, an alkali metal periodate, a hypochlorite salt, hypochlorous acid and a halogen amine.
Claim 7
Dependent Claim
46 words
A wound healing kit, comprising: a first container having therein a composition comprised of water soluble, lyophilized, atelopeptide collagen and a pH buffer; a second container having therein an alkali metal iodide and an oxidizing agent; and a third container having therein an alkali metal iodate.
Claim 8
Dependent Claim
46 words
A wound healing kit, comprising: a first container having therein a composition comprised of water soluble, lyophilized, atelopeptide collagen and a pH buffer; a second container having therein an alkali metal iodide and an oxidizing agent; and a third container having therein an alkali metal iodate.
Claim 9
Dependent Claim
17 words
The wound healing kit as claimed in claim 6, wherein the alkali metal iodide is potassium iodide.
Claim 10
Dependent Claim
17 words
The wound healing kit as claimed in claim 6, wherein the alkali metal iodate is potassium iodate.
Claim 11
Dependent Claim
16 words
The wound healing kit as claimed in claim 6, wherein the oxidizing agent is citric acid.
Claim 12
Dependent Claim
83 words
A wound healing kit in the form of three interconnected departmental containers including a first container having therein a composition comprised of water soluble, lyophilized, atelopeptide collagen and a pH buffer; a second container having therein an alkali metal iodide and an oxidizing agent; and a third container having therein an alkali metal iodate; wherein the first container, second container and third container are separated from each other by breakable seals which seals when broken allow intermixing of any contents in the containers.
Claim 13
Dependent Claim
83 words
A wound healing kit in the form of three interconnected departmental containers including a first container having therein a composition comprised of water soluble, lyophilized, atelopeptide collagen and a pH buffer; a second container having therein an alkali metal iodide and an oxidizing agent; and a third container having therein an alkali metal iodate; wherein the first container, second container and third container are separated from each other by breakable seals which seals when broken allow intermixing of any contents in the containers.
References Cited (Backward Citations)
US4347234A
Cited
US4552138A
Cited
US4592864A
Cited
US4600533A
Cited
US4851513A
Cited
US4849141A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-07-07 | 1996-01-06 | 1996-07-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-07-07 | 2000-01-06 | 2000-07-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-07-07 | 2004-01-06 | 2004-07-07 | $7700.00 | Window Closed / Lapsed |