US5145644A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Hydrogen peroxide destroying compositions and methods of making and using same
Assignee: Johnson and Johnson Surgical Vision Inc
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Filing: 1990-12-20
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Granted: 1992-09-08
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Expires: 2010-12-20
Abstract
Abstract Compostions, and method useful for making such compositions and for using such compositions, which are useful to destroy hydrogen peroxide in a liquid aqueous medium, such as that used to disinfect contact lenses, are disclosed. The composition comprises at least one item containing a hydrogen peroxide destroying component, e.g., catalase, effective when released in a liquid aqueous medium to destroy or cause the destruction of hydrogen peroxide present in the liquid aqueous medium, and a barrier coating located on the at least one item and acting to substantially prevent the release of the hydrogen peroxide destroying component for a period of time after the composition is initially contacted with a hydrogen peroxide-containing liquid aqueous medium. The barrier coating comprises a water soluble coating component, e.g., hydroxypropylmethyl cellulose, and is formed by a method which comprises applying a mixture comprising water, a ketone and the water soluble coating component to produce at least one precoated item; and removing water and ketone from the precoated item or items. In a preferred embodiment, the composition includes a cleaning enzyme to remove debris from the contact lens, in particular at the same time the lens is being disinfected.
Inventors
- 👤 John Y. Park
- 👤 James N. Cook
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 03:39
CPC Classifications
C; C11; C11D; C11D17/00; C11D17/0047; C11D17/0065; C11D17/0073; A; A01; A01N; A01N59/00; A61; A61L; A61L12/00; A61L12/08; A61L12/12; A61L12/124; A61L12/126; C11D17/0039; C11D3/00; C11D3/0005; C11D3/0078; C11D3/16; C11D3/38; C11D3/386; C11D3/38654
Claims Analysis
Total Claims: 33
Claim 1
Independent Claim
160 words
A method for producing a hydrogen peroxide destroying composition useful for destroying residual hydrogen peroxide in a hydrogen peroxide-containing liquid aqueous medium comprising: providing an item containing a hydrogen peroxide destroying component effective when released in a hydrogen peroxide-containing liquid aqueous medium to destroy or cause the destruction of hydrogen peroxide present in the hydrogen peroxide-containing liquid aqueous medium; and applying to said item a mixture comprising water, a ketone component and a water soluble coating component in an amount sufficient to coat substantially all of said item with said mixture and form a precoated item; and removing water and said ketone component from said precoated item and forming a coated item which includes a coating containing said water soluble coating component and is structured to delay the release of said hydrogen peroxide destroying component in the hydrogen peroxide-containing liquid aqueous medium for a period of time after said coated item is introduced into the hydrogen peroxide-containing liquid aqueous medium.
Claim 2
Independent Claim
160 words
A method for producing a hydrogen peroxide destroying composition useful for destroying residual hydrogen peroxide in a hydrogen peroxide-containing liquid aqueous medium comprising: providing an item containing a hydrogen peroxide destroying component effective when released in a hydrogen peroxide-containing liquid aqueous medium to destroy or cause the destruction of hydrogen peroxide present in the hydrogen peroxide-containing liquid aqueous medium; and applying to said item a mixture comprising water, a ketone component and a water soluble coating component in an amount sufficient to coat substantially all of said item with said mixture and form a precoated item; and removing water and said ketone component from said precoated item and forming a coated item which includes a coating containing said water soluble coating component and is structured to delay the release of said hydrogen peroxide destroying component in the hydrogen peroxide-containing liquid aqueous medium for a period of time after said coated item is introduced into the hydrogen peroxide-containing liquid aqueous medium.
Claim 3
Dependent Claim
72 words
The method of claim 1 wherein said mixture comprises a liquid containing a minor amount by volume of water and a major amount by volume of said ketone component based on the total of water and said ketone component present in said mixture, and said water soluble coating component is selected form the group consisting of water soluble cellulose derivatives, water soluble methacrylate-based polymers, water soluble vinyl pyrrolidone-based polymers and mixtures thereof.
Claim 4
Dependent Claim
42 words
The method of claim 1 wherein said ketone component has up to about 6 carbon atoms per molecule and said water soluble coating component is selected from the group consisting of water soluble cellulose ethers, water soluble cellulose esters and mixtures thereof.
Claim 5
Dependent Claim
20 words
The method of claim 1 wherein said ketone component is acetone and said water soluble coating component is hydroxypropylmethyl cellulose.
Claim 6
Dependent Claim
25 words
The method of claim 1 wherein said hydrogen peroxide destroying component comprises catalase and said mixture comprises about 20% or less by volume of water.
Claim 7
Dependent Claim
34 words
The method of claim 1 wherein said mixture further comprises an enzyme capable of removing debris from a contact lens located in the hydrogen peroxide-containing liquid aqueous medium, said coated item includes said enzyme.
Claim 8
Dependent Claim
37 words
The method of claim 6 wherein said coated item is structured to release said enzyme in the hydrogen peroxide-containing liquid aqueous medium before said hydrogen peroxide destroying component is released in the hydrogen peroxide-containing liquid aqueous medium.
Claim 9
Dependent Claim
43 words
The method of claim 7 wherein said enzyme is Subtilisin A, said hydrogen peroxide destroying component comprises catalase, said water soluble coating component is hydroxypropylmethyl cellulose, said ketone component is acetone and said mixture comprises about 20% or less by volume of water.
Claim 10
Dependent Claim
45 words
The method of claim 8 which further comprises: combining a plurality of said coated items and an enzyme capable of removing debris from a contact lens located in the hydrogen peroxide-containing liquid aqueous medium to form a combination; and forming a tablet from said combination.
Claim 11
Dependent Claim
129 words
The method of claim 1 which further comprises: applying to said coated item a second mixture comprising water, a second ketone component, a second water soluble coating component and an enzyme capable of removing debris from a contact lens located in the hydrogen peroxide-containing liquid aqueous medium to coat substantially all of said coated item with said second mixture and form a second precoated item; and removing water and said second ketone component from said second precoated item and forming a second coated item which includes a second coating containing said second coating component and said enzyme, said second coated item being structured to release said enzyme in the hydrogen peroxide-containing liquid aqueous medium before said hydrogen peroxide destroying component is released in the hydrogen peroxide-containing liquid aqueous medium.
Claim 12
Dependent Claim
77 words
The method of claim 10 wherein said second mixture comprises a liquid containing a minor amount by volume of water and a major amount by volume of said second ketone component based on the total of water and said second ketone component present in said second mixture, and said second water soluble coating component is selected form the group consisting of water soluble cellulose derivatives, water soluble methacrylate-based polymers, water soluble vinyl pyrrolidone-based polymers and mixtures thereof.
Claim 13
Dependent Claim
13 words
The method of claim 10 wherein said hydrogen peroxide destroying component comprises catalase.
Claim 14
Dependent Claim
46 words
The method of claim 10 wherein said enzyme is Subtilisin A, said hydrogen peroxide destroying component comprises catalase, said second water soluble coating component is hydroxypropylmethyl cellulose, said second ketone component is acetone and said second mixture comprises about 20% or less by volume of water.
Claim 15
Dependent Claim
45 words
The method of claim 1 which further comprises: combining a plurality of said coated items and an enzyme capable of removing debris from a contact lens located in the hydrogen peroxide-containing liquid aqueous medium to form a combination; and forming a tablet from said combination.
Claim 16
Dependent Claim
106 words
A composition comprising an item containing a hydrogen peroxide destroying component effective when released in a liquid aqueous medium to destroy or cause the destruction of hydrogen peroxide present in the liquid aqueous medium, and a barrier coating located on said item and acting to substantially prevent the release of said hydrogen peroxide destroying component for a period of time after said composition is initially contacted with a hydrogen peroxide-containing liquid aqueous medium, said barrier coating comprising a water soluble coating component and being derived from a mixture comprising water, a ketone component and said water soluble coating component, which mixture is applied to said item.
Claim 17
Dependent Claim
106 words
A composition comprising an item containing a hydrogen peroxide destroying component effective when released in a liquid aqueous medium to destroy or cause the destruction of hydrogen peroxide present in the liquid aqueous medium, and a barrier coating located on said item and acting to substantially prevent the release of said hydrogen peroxide destroying component for a period of time after said composition is initially contacted with a hydrogen peroxide-containing liquid aqueous medium, said barrier coating comprising a water soluble coating component and being derived from a mixture comprising water, a ketone component and said water soluble coating component, which mixture is applied to said item.
Claim 18
Dependent Claim
72 words
The composition of claim 15 wherein said mixture comprises a liquid comprising a minor amount by volume of water and a major amount by volume of said ketone component based on the total of water and said ketone component present in said mixture, and said water soluble coating component is selected from the group consisting of water soluble cellulose derivatives, water soluble methacrylate-based polymers, water soluble vinyl pyrrolidone-based polymers and mixtures thereof.
Claim 19
Dependent Claim
42 words
The composition of claim 15 wherein said ketone component has up to about 6 carbon atoms per molecule and said water soluble coating component is selected from the group consisting of water soluble cellulose ethers, water soluble cellulose esters and mixtures thereof.
Claim 20
Dependent Claim
20 words
The composition of claim 15 wherein said ketone component is acetone and said water soluble coating component is hydroxypropylmethyl cellulose.
Claim 21
Dependent Claim
25 words
The composition of claim 15 wherein said hydrogen peroxide destroying component comprises catalase and said mixture comprises about 20% or less by volume of water.
Claim 22
Dependent Claim
60 words
The composition of claim 15 which further comprises an enzyme capable of removing debris from a contact lens located in the liquid aqueous medium, said composition including an effective amount of said enzyme to substantially remove at least one type of debris from a debris laden contact lens located in the liquid aqueous medium in which said enzyme is released.
Claim 23
Dependent Claim
43 words
The composition of claim 20 wherein said enzyme is Subtilisin A, said hydrogen peroxide destroying component comprises catalase, said water soluble coating component is hydroxypropylmethyl cellulose, said ketone component is acetone and said mixture comprises about 20% or less by volume of water.
Claim 24
Dependent Claim
50 words
The composition of claim 20 which has a layered structure with said item being substantially coated with a first coating comprising said water soluble coating component to form a first coated item which is substantially coated with a second coating comprising a second water soluble coating component and said enzyme.
Claim 25
Dependent Claim
13 words
The composition of claim 22 wherein said hydrogen peroxide destroying component comprises catalase.
Claim 26
Dependent Claim
27 words
The composition of claim 22 wherein said enzyme is Subtilisin A, said hydrogen peroxide destroying component comprises catalase, and said water soluble coating component includes hydroxypropylmethyl cellulose.
Claim 27
Dependent Claim
25 words
The composition of claim 20 which is in the form of a tablet including a plurality of said items with said barrier coating located thereon.
Claim 28
Dependent Claim
13 words
The composition of claim 25 wherein said hydrogen peroxide destroying component comprises catalase.
Claim 29
Dependent Claim
27 words
The composition of claim 25 wherein said enzyme is Subtilisin A, said hydrogen peroxide destroying component comprises catalase, and said water soluble coating component includes hydroxypropylmethyl cellulose.
Claim 30
Independent Claim
144 words
A method of disinfecting a lens comprising: contacting a lens to be disinfected with a hydrogen peroxide-containing liquid aqueous medium at effective lens disinfecting conditions, thereby disinfecting said lens; and contacting said hydrogen peroxide-containing aqueous liquid medium with a composition comprising an item containing a hydrogen peroxide destroying component effective when released in a liquid aqueous medium to destroy or cause the destruction of hydrogen peroxide present in the liquid aqueous medium, and a barrier coating located on said item and acting to substantially prevent the release of said hydrogen peroxide destroying component for a period of time after said composition is initially contacted with said hydrogen peroxide-containing liquid aqueous medium, said barrier coating comprising a water soluble coating component and being derived from a mixture comprising water, a ketone component and said water soluble coating component, which mixture is applied to said item.
Claim 31
Independent Claim
144 words
A method of disinfecting a lens comprising: contacting a lens to be disinfected with a hydrogen peroxide-containing liquid aqueous medium at effective lens disinfecting conditions, thereby disinfecting said lens; and contacting said hydrogen peroxide-containing aqueous liquid medium with a composition comprising an item containing a hydrogen peroxide destroying component effective when released in a liquid aqueous medium to destroy or cause the destruction of hydrogen peroxide present in the liquid aqueous medium, and a barrier coating located on said item and acting to substantially prevent the release of said hydrogen peroxide destroying component for a period of time after said composition is initially contacted with said hydrogen peroxide-containing liquid aqueous medium, said barrier coating comprising a water soluble coating component and being derived from a mixture comprising water, a ketone component and said water soluble coating component, which mixture is applied to said item.
Claim 32
Dependent Claim
72 words
The method of claim 28 wherein said mixture comprises a liquid containing a minor amount by volume of water and a major amount by volume of said ketone component based on the total of water and said ketone component present in said mixture, and said water soluble coating component is selected from the group consisting of water soluble cellulose derivatives, water soluble methacrylate-based polymers, water soluble vinyl pyrrolidone-based polymers and mixtures thereof.
Claim 33
Dependent Claim
58 words
The method of claim 28 wherein said composition further comprises an enzyme capable of removing debris from a contact lens located in said hydrogen peroxide-containing liquid aqueous medium, said composition being structured to release said enzyme in said hydrogen peroxide-containing liquid aqueous medium before said hydrogen peroxide destroying component is released in said hydrogen peroxide-containing liquid aqueous medium.
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| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 1995-09-08 | 1996-03-09 | 1996-09-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-09-08 | 2000-03-09 | 2000-09-08 | $3760.00 | Window Closed / Lapsed |
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