US5202268A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Multi-layered test card for the determination of substances in liquids
Assignee: Medtox Scientific Inc
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Filing: 1988-12-30
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Granted: 1993-04-13
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Expires: 2008-12-30
Abstract
Abstract A composite device for detecting or determining the presence of components in liquids is described. The device has, in combination at least a first and a second layer of porous material in contact with each other, at least one sample receiving site in said device and at least one reaction site connected to the sample receiving site via the second layer. A pre-determined liquid flow path in and through said layer is defined by liquid barrier means located in said layers whereby liquid deposited at the sample site is transferred to the reaction site along a path from one member to the other.
Inventors
- 👤 Raymond Kuhn
- 👤 Gene H. MacDonald
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 13:49
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/543; G01N33/54366; G01N33/54386; G01N33/54387; G01N33/54388; G01N33/54389; B; B01; B01L; B01L3/00; B01L3/50; B01L3/502; B01L3/5023; B01L2200/00; B01L2200/16; B01L2300/00; B01L2300/08; B01L2300/0809; B01L2300/0816; B01L2300/0825; B01L2300/0861; B01L2300/0867; B01L2400/00; B01L2400/08; B01L2400/084; Y; Y10; Y10S; Y10S435/00; Y10S435/97; Y10S436/00; Y10S436/807; Y10S436/81
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
115 words
A composite device for detecting or determining the presence of components in liquids which comprises in combination at least a first and a second layer of porous material in contact with each other and having differential wicking characteristics, at least one sample receiving site in said device on said first layer, and at least one reaction site on said first layer said reaction site being distant from said sample receiving site and in communication with said sample receiving site via said second layer and a liquid flow path in and through said layers whereby liquid deposited at the sample site is transferred to the reaction site along a path from one layer to the other.
Claim 2
Dependent Claim
115 words
A composite device for detecting or determining the presence of components in liquids which comprises in combination at least a first and a second layer of porous material in contact with each other and having differential wicking characteristics, at least one sample receiving site in said device on said first layer, and at least one reaction site on said first layer said reaction site being distant from said sample receiving site and in communication with said sample receiving site via said second layer and a liquid flow path in and through said layers whereby liquid deposited at the sample site is transferred to the reaction site along a path from one layer to the other.
Claim 3
Dependent Claim
13 words
The device of claim 1 wherein the porous material is flat and planar.
Claim 4
Dependent Claim
27 words
The device of claim 2 wherein the porous material is nylon, polytetrafluoroethylene, fluorinated ethylene-propylene polymers, glass fibers, polyvinyl chloride, cellulose acetate, polyvinylidene difluoride, cellulose nitrate or polypropylene.
Claim 5
Dependent Claim
26 words
The device of claim 2 wherein each layer is hydrophobic, or each layer is hydrophilic, or either layer is hydrophobic and the other layer is hydrophilic.
Claim 6
Dependent Claim
26 words
The device of claim 1 wherein there is present at said at least one reaction site a binding partner of an immunologic component to be determined.
Claim 7
Dependent Claim
14 words
The device of claim 5 wherein there are present a plurality of reaction sites.
Claim 8
Dependent Claim
22 words
The device of claim 5 wherein the immunologic binding partner is an antibody and the component to be determined is an antigen.
Claim 9
Dependent Claim
40 words
The device of claim 7 wherein there is present in said second layer in the liquid flow path prior to the reaction site an antigen corresponding to the component to be determined which antigen is conjugated to an indicator system.
Claim 10
Dependent Claim
12 words
The device of claim 8 wherein the indicator system is colloidal gold.
Claim 11
Dependent Claim
40 words
The device of claim 7 wherein there is present in said second layer in the liquid flow path prior to the reaction site an antibody reactive with the antigen to be determined which antibody is conjugated to an indicator system.
Claim 12
Dependent Claim
12 words
The device of claim 10 wherein the indicator system is colloidal gold.
Claim 13
Dependent Claim
29 words
The device of claim 1 wherein the barriers are slots, discontinuities, welds, or compressions and are located in the liquid pathway so as to control flow direction and rates.
Claim 14
Dependent Claim
39 words
The device of claim 1 wherein there are present in said device in the liquid flow path prior to the reaction site reactants whereby when sufficient liquid flows along said pathway, said reactants are delivered to said reaction site.
Claim 15
Dependent Claim
25 words
The device of claim 12 wherein each layer is protein-binding or each layer is non-protein-binding or either layer is protein-binding and the other is non-protein-binding.
Claim 16
Dependent Claim
14 words
The device of claim 12 wherein each layer has the same or different porosities.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1996-04-12 | 1996-10-12 | 1997-04-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-04-12 | 2000-10-12 | 2001-04-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-04-12 | 2004-10-12 | 2005-04-13 | $7700.00 | Window Closed / Lapsed |