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US5215716A Expired / Lapsed US ⏱️ 0.0 years remaining

Integral multilayer analytical element

Assignee: Fujifilm Holdings Corp
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Filing: 1991-03-11
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Granted: 1993-06-01
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Expires: 2011-03-11
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Abstract

Abstract An integral multilayer analytical element comprising a reagent layer containing an indicator reagent composition capable of producing a detectable change corresponding to an analyte and a porous spreading layer composed of a fibrous fabric superposed on the reagent layer, wherein the yarn of said fabric comprises fibers having roughed surface, and an integral multilayer analytical element comprising a water-absorptive layer containing a hydrophilic polymer and a porous spreading layer composed of a fibrous fabric containing an indicator reagent composition capable of producing a detectable change corresponding to an analyte superposed on the water-absorptive layer, wherein the yarn of said fabric comprises fibers having roughed surface. The rouging is carried out, for example, by alkali etching.

Inventors

  • 👤 Fuminori Arai

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-05 23:00
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/52; G01N33/525

Claims Analysis

Total Claims: 14
Claim 1
Independent Claim 146 words
In an integral multilayer analytical element comprising a reagent layer containing an indicator reagent composition capable of producing a detectable change corresponding to an analyte and a porous spreading layer composed of a fibrous fabric superposed on the reagent layer, the improvement which comprises said fabric being composed of fibers having a roughed surface formed by alkali etching, the fabric having an exposed and unexposed face, the fibers having a roughed surface comprising roughed portions being at least on the exposed face of the fabric, and wherein the depth of the roughness of the roughed surface in the direction perpendicular to the fiber axis is from 0.2 to 0.7 μm, and the roughed portions being further roughed with a fine roughness of a depth from about 50 nm to 200 nm, the density of the roughness of the roughed surface being from about 1 to 200/μm.
Claim 2
Dependent Claim 146 words
In an integral multilayer analytical element comprising a reagent layer containing an indicator reagent composition capable of producing a detectable change corresponding to an analyte and a porous spreading layer composed of a fibrous fabric superposed on the reagent layer, the improvement which comprises said fabric being composed of fibers having a roughed surface formed by alkali etching, the fabric having an exposed and unexposed face, the fibers having a roughed surface comprising roughed portions being at least on the exposed face of the fabric, and wherein the depth of the roughness of the roughed surface in the direction perpendicular to the fiber axis is from 0.2 to 0.7 μm, and the roughed portions being further roughed with a fine roughness of a depth from about 50 nm to 200 nm, the density of the roughness of the roughed surface being from about 1 to 200/μm.
Claim 3
Dependent Claim 25 words
The analytical element of claim 1 wherein said yarn is filament yarn composed of long fibers and said fabric is woven fabric or knitted fabric.
Claim 4
Dependent Claim 21 words
The analytical element of claim 1 wherein said yarn is spun yarn, and said fabric is woven fabric or knitted fabric.
Claim 5
Dependent Claim 22 words
The analytical element of claim 1, claim 2 or claim 3 wherein said reagent layer is provided on a light-transmissive water-impermeable support.
Claim 6
Dependent Claim 25 words
The analytical element of claim 1, claim 2 or claim 3 wherein said reagent layer is provided on a light-reflective or opaque and water-impermeable support.
Claim 7
Dependent Claim 17 words
The analytical element of claim 5, wherein said reagent layer is provided on a light-transmissive water-impermeable support.
Claim 8
Dependent Claim 20 words
The analytical element of claim 5, wherein said reagent layer is provided on a light-reflective or opaque and water-impermeable support.
Claim 9
Dependent Claim 149 words
In an integral multilayer analytical element comprising a water-absorptive layer containing a hydrophilic polymer and a porous spreading layer composed of a fibrous fabric containing an indicator composition capable of producing a detectable change corresponding to an analyte superposed on the water-absorptive layer, the improvement which comprises said fabric being composed of fibers having a roughed surface formed by alkali etching, the fabric having an exposed and unexposed face, the fibers having a roughed surface comprising roughed portions being at least on the exposed face of the fabric, and wherein the depth of the roughness of the roughed surface in the direction perpendicular to the fiber axis is from 0.2 to 0.7 μm, and the roughed portions being further roughed with a fine roughness of a depth from about 50 nm to 200 nm, the density of the roughness of the roughed surface being from about 1 to 200/μm.
Claim 10
Dependent Claim 149 words
In an integral multilayer analytical element comprising a water-absorptive layer containing a hydrophilic polymer and a porous spreading layer composed of a fibrous fabric containing an indicator composition capable of producing a detectable change corresponding to an analyte superposed on the water-absorptive layer, the improvement which comprises said fabric being composed of fibers having a roughed surface formed by alkali etching, the fabric having an exposed and unexposed face, the fibers having a roughed surface comprising roughed portions being at least on the exposed face of the fabric, and wherein the depth of the roughness of the roughed surface in the direction perpendicular to the fiber axis is from 0.2 to 0.7 μm, and the roughed portions being further roughed with a fine roughness of a depth from about 50 nm to 200 nm, the density of the roughness of the roughed surface being from about 1 to 200/μm.
Claim 11
Dependent Claim 25 words
The analytical element of claim 8 wherein said yarn is filament yarn composed of long fibers and said fabric is woven fabric or knitted fabric.
Claim 12
Dependent Claim 21 words
The analytical element of claim 8 wherein said yarn is spun yarn, and said fabric is woven fabric or knitted fabric.
Claim 13
Dependent Claim 20 words
The analytical element of claim 1 or 8 wherein said reagent composition contains a diazonium salt or a tetrazolium salt.
Claim 14
Dependent Claim 23 words
The analytical element of claim 1 or 8 wherein the fibrous fabric is initially hydrophobic and is made hydrophilic by the alkali etching.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1996-05-31 1996-11-30 1997-06-01 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2000-05-31 2000-11-30 2001-06-01 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2004-05-31 2004-11-30 2005-06-01 $7700.00 Window Closed / Lapsed

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