US5224492A
Expired / Lapsed
US
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Thermotherapy apparatus
Assignee: Omron Corp
•
Filing: 1991-06-11
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Granted: 1993-07-06
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Expires: 2011-06-11
Abstract
Abstract In a CT image of a living body, contours of internal organs thereof are discriminated. Parameters are beforehand stored in a memory for a plurality of internal organs of the living body. Applicators are attached onto the living body and then a high frequency power is applied to electrodes disposed therein so as to heat an internal portion of the body. Based on an intensity of an electric field generated in the body due to the applied power and the parameters stored in the memory, a temperature distribution on the CT image is estimated. To retain an estimated temperature of an objective tumor at a predetermined target temperature, the high frequency power and the cooling water in the applicators are controlled. In the estimation of the temperature distribution, the parameters of the living body are repeatedly corrected to minimize a discrepancy between a temperature measured at a preset position and an estimated temperature associated therewith.
Inventors
- 👤 Noriyuki Takahashi
- 👤 Tamaki Sakamoto
- 👤 Jun Shimoyama
- 👤 Eiji Kasai
- 👤 Makoto Saito
- 👤 Jin-ichi Matsuda
- 👤 Kazuo Kato
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 20:30
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/41; A61B5/414; A61B5/417; A61B5/01; A61B5/015; A61N; A61N1/00; A61N1/40; A61N1/403
Claims Analysis
Total Claims: 29
Claim 1
Independent Claim
360 words
A thermotherapy apparatus including applicators each having an electrode for applying high frequency power to a living body, each applicator comprising a bolus for cooling a surface of the living body and thermostatic liquid circulation means for circulating a thermostatic liquid in said bolus, high frequency power generating means for generating high frequency power applied to said electrodes, temperature measuring means for measuring a temperature of a predetermined position of the living body, and heating condition setting means for setting a heating condition, said thermotherapy apparatus further comprising: means for acquiring a cross-sectional image of the living body; means for storing parameters of textures or viscera of the living body; temperature distribution estimation means for repeatedly correcting values of the stored parameters of the living body to minimize, based on the acquired cross-sectional image, the stored parameters of the living body and a preset heating condition, a discrepancy between a temperature repeatedly measured at the predetermined position of the living body by said temperature measuring means and a temperature of the predetermined position of the living body obtained from an estimated temperature distribution, thereby estimating a temperature distribution on the cross-sectional image; means for setting a tumor area on the cross-sectional image as an object of thermotherapy; means for attaining, based on the estimated temperature distribution, a hot spot having a temperature exceeding a predetermined temperature; output control means for applying the high frequency power to said electrodes when a maximum temperature of the tumor area is less than a preset control temperature and for decreasing the high frequency power applied to said electrodes when the maximum temperature of the tumor area is not less than the preset control temperature; and thermostatic liquid control means for decreasing a temperature of the thermostatic liquid circulating in the bolus or increasing a flow rate of the thermostatic liquid circulating in the bolus when the hot spot is larger in size than the tumor area and for increasing the temperature of the thermostatic liquid circulating in the bolus or decreasing the flow rate of the thermostatic liquid circulating in the bolus when the hot spot is smaller in size than the tumor area.
Claim 2
Dependent Claim
360 words
A thermotherapy apparatus including applicators each having an electrode for applying high frequency power to a living body, each applicator comprising a bolus for cooling a surface of the living body and thermostatic liquid circulation means for circulating a thermostatic liquid in said bolus, high frequency power generating means for generating high frequency power applied to said electrodes, temperature measuring means for measuring a temperature of a predetermined position of the living body, and heating condition setting means for setting a heating condition, said thermotherapy apparatus further comprising: means for acquiring a cross-sectional image of the living body; means for storing parameters of textures or viscera of the living body; temperature distribution estimation means for repeatedly correcting values of the stored parameters of the living body to minimize, based on the acquired cross-sectional image, the stored parameters of the living body and a preset heating condition, a discrepancy between a temperature repeatedly measured at the predetermined position of the living body by said temperature measuring means and a temperature of the predetermined position of the living body obtained from an estimated temperature distribution, thereby estimating a temperature distribution on the cross-sectional image; means for setting a tumor area on the cross-sectional image as an object of thermotherapy; means for attaining, based on the estimated temperature distribution, a hot spot having a temperature exceeding a predetermined temperature; output control means for applying the high frequency power to said electrodes when a maximum temperature of the tumor area is less than a preset control temperature and for decreasing the high frequency power applied to said electrodes when the maximum temperature of the tumor area is not less than the preset control temperature; and thermostatic liquid control means for decreasing a temperature of the thermostatic liquid circulating in the bolus or increasing a flow rate of the thermostatic liquid circulating in the bolus when the hot spot is larger in size than the tumor area and for increasing the temperature of the thermostatic liquid circulating in the bolus or decreasing the flow rate of the thermostatic liquid circulating in the bolus when the hot spot is smaller in size than the tumor area.
Claim 3
Dependent Claim
43 words
A thermotherapy apparatus in accordance with claim 1 further including output control means for controlling an output from said high frequency power generation means based on a temperature of a pre-specified area in the living body estimated by said temperature distribution estimation means.
Claim 4
Dependent Claim
49 words
A thermotherapy apparatus in accordance with claim 1 further including: means for beforehand storing therein a plurality of preset heating conditions; and means for selecting from the plural heating conditions stored in said storing means a heating condition suitable for the acquired cross-sectional image and the preset tumor area.
Claim 5
Dependent Claim
243 words
A thermotherapy apparatus including applicators each having an electrode for applying high frequency power to a living body, high frequency power generating means for generating high frequency power applied to said electrodes, temperature measuring means for measuring a temperature of a predetermined position of the living body, and heating condition setting means for setting a heating condition, said thermotherapy apparatus further comprising: means for acquiring a cross-sectional image of the living body; means for storing parameters of textures or viscera of the living body; temperature distribution estimation means for repeatedly correcting values of the parameters of the living body to minimize, based on the acquired cross-sectional image, the stored parameters of the living body and a preset heating condition, a discrepancy between a temperature repeatedly measured at the predetermined position of the living body by said temperature measuring means and a temperature of the predetermined position of the living body obtained from an estimated temperature distribution, thereby estimating a temperature distribution on the cross-sectional image; and parameter estimations means for estimation at least one of the parameters of the living body as the applicators are continuously driven based on the parameters of the living body employed to estimate the temperature distribution, the estimated temperature determined by the temperature distribution estimation means and the measured temperature of the living body, said parameter estimation means repeatedly estimation to correct at least one of the parameters of the living body used by said temperature estimation means.
Claim 6
Dependent Claim
243 words
A thermotherapy apparatus including applicators each having an electrode for applying high frequency power to a living body, high frequency power generating means for generating high frequency power applied to said electrodes, temperature measuring means for measuring a temperature of a predetermined position of the living body, and heating condition setting means for setting a heating condition, said thermotherapy apparatus further comprising: means for acquiring a cross-sectional image of the living body; means for storing parameters of textures or viscera of the living body; temperature distribution estimation means for repeatedly correcting values of the parameters of the living body to minimize, based on the acquired cross-sectional image, the stored parameters of the living body and a preset heating condition, a discrepancy between a temperature repeatedly measured at the predetermined position of the living body by said temperature measuring means and a temperature of the predetermined position of the living body obtained from an estimated temperature distribution, thereby estimating a temperature distribution on the cross-sectional image; and parameter estimations means for estimation at least one of the parameters of the living body as the applicators are continuously driven based on the parameters of the living body employed to estimate the temperature distribution, the estimated temperature determined by the temperature distribution estimation means and the measured temperature of the living body, said parameter estimation means repeatedly estimation to correct at least one of the parameters of the living body used by said temperature estimation means.
Claim 7
Dependent Claim
43 words
A thermotherapy apparatus in accordance with claim 4 further including output control means for controlling an output from said high frequency power generation means based on a temperature of a pre-specified area in the living body estimated by said temperature distribution estimation means.
Claim 8
Dependent Claim
36 words
A thermotherapy apparatus in accordance with claim 4 wherein each said applicator includes: a bolus for cooling a surface of the living body; and thermostatic liquid circulation means for circulating a thermostatic liquid in said bolus.
Claim 9
Dependent Claim
58 words
A thermotherapy apparatus in accordance with claim 6 further including thermostatic liquid control means for controlling, based on a temperature distribution of a pre-specified area in the living body estimated by said temperature distribution estimate means, at least either one of a temperature and a circulating flow rate of the thermostatic liquid circulated by said thermostatic circulate means.
Claim 10
Dependent Claim
65 words
A thermotherapy apparatus in accordance with claim 4 further including: means for setting a tumor area as an object of a thermotherapy on the cross-sectional image; means for beforehand storing therein a plurality of preset heating conditions; and means for selecting from the plural heating conditions stored in said store means a heating condition suitable for the acquired cross-sectional image and the preset tumor area.
Claim 11
Dependent Claim
178 words
A thermotherapy apparatus in accordance with claim 6, further comprising: means for setting a tumor area on the cross-sectional image as an object of thermotherapy; means for attaining, based on the estimated temperature distribution, a hot spot having a temperature exceeding a predetermined temperature; output control means for applying the high frequency power to said electrodes when a maximum temperature of the tumor area is less than a preset control temperature and for decreasing the high frequency power applied to said electrodes when the maximum temperature of the tumor area is not less than the preset control temperature; and thermostatic liquid control means for decreasing a temperature of the thermostatic liquid circulating in the bolus or increasing a flow rate of the thermostatic liquid circulating in the bolus when the hot spot is larger in size than the tumor area and for increasing the temperature of the thermostatic liquid circulating in the bolus or decreasing the flow rate of the thermostatic liquid circulating in the bolus when the hot spot is smaller in size than the tumor area.
Claim 12
Dependent Claim
156 words
A thermotherapy apparatus including applicators each having an electrode for applying high frequency power to a living body, and high frequency power generating means for generating high frequency power applied to said electrodes, comprising: means for acquiring a cross-sectional image of the living body; means for storing parameters of textures or viscera of the living body; treatment condition reporting means for determining and for reporting, based on the acquired cross-sectional image, at least one optimal condition selected from the group of conditions including a size and a position of each electrode, the amount of high frequency power applied to each electrode, and a power application period of time; temperature distribution estimation means for estimating a temperature distribution on the cross-sectional image of the living body based on the stored parameters of the living body under the condition reported by the treatment condition reporting means; and output means for displaying or for recording the estimated temperature distribution.
Claim 13
Dependent Claim
156 words
A thermotherapy apparatus including applicators each having an electrode for applying high frequency power to a living body, and high frequency power generating means for generating high frequency power applied to said electrodes, comprising: means for acquiring a cross-sectional image of the living body; means for storing parameters of textures or viscera of the living body; treatment condition reporting means for determining and for reporting, based on the acquired cross-sectional image, at least one optimal condition selected from the group of conditions including a size and a position of each electrode, the amount of high frequency power applied to each electrode, and a power application period of time; temperature distribution estimation means for estimating a temperature distribution on the cross-sectional image of the living body based on the stored parameters of the living body under the condition reported by the treatment condition reporting means; and output means for displaying or for recording the estimated temperature distribution.
Claim 14
Dependent Claim
41 words
A thermotherapy apparatus in accordance with claim 10 wherein each said applicator includes a bolus for cooling a surface of the living body, and wherein the apparatus further includes thermostatic liquid circulation means for circulating a thermostatic liquid in said bolus.
Claim 15
Dependent Claim
39 words
A thermotherapy appartus in accordance with claim 11 wherein said treatment condition reporting means reports as the optimal treatment condition at least a temperature of the thermostatic liquid in each said bolus and a pre-cooling period of time thereof.
Claim 16
Dependent Claim
105 words
A thermotherapy schedule support apparatus comprising: means for inputting thereto a cross-sectional image of a living body; means for discriminating boundaries between different textures of the living body in the inputted cross-sectional image; store means for beforehand storing therein parameters of the living body respectively related to a plurality of textures of the living body; and temperature estimate means for estimating in association with the inputted cross-sectional image, with use of an intensity of an electric field applied to the living body and the parameters stored in said storing means, a temperature distribution of the living body generated due to the electric field applied thereto.
Claim 17
Dependent Claim
105 words
A thermotherapy schedule support apparatus comprising: means for inputting thereto a cross-sectional image of a living body; means for discriminating boundaries between different textures of the living body in the inputted cross-sectional image; store means for beforehand storing therein parameters of the living body respectively related to a plurality of textures of the living body; and temperature estimate means for estimating in association with the inputted cross-sectional image, with use of an intensity of an electric field applied to the living body and the parameters stored in said storing means, a temperature distribution of the living body generated due to the electric field applied thereto.
Claim 18
Dependent Claim
33 words
A therapy schedule support apparatus in accordance with claim 13 wherein said discriminating means performs an image processing on the inputted cross-sectional image to extract contours of the textures of the living body.
Claim 19
Dependent Claim
29 words
A therapy schedule support apparatus in accordance with claim 13 wherein said discriminating means includes means for inputting thereto data representing contours of the textures of the living body.
Claim 20
Dependent Claim
55 words
A therapy schedule support apparatus in accordance with claim 13 further including: means for measuring a temperature of a predetermined position of the living body; and means for correcting the parameters of the living body based on a difference between a temperature measured by said measuring means and a temperature estimated by said estimate means.
Claim 21
Dependent Claim
33 words
A therapy schedule support apparatus in accordance with claim 16, wherein said correcting means corrects the parameters of the living body such that the difference between the measured and estimated temperatures is decreased.
Claim 22
Dependent Claim
47 words
A therapy schedule support apparatus in accordance with claim 17 wherein said correcting means estimates parameters of the living body based on the parameters of the living body employed by said estimate means and the measured and estimated temperatures associated with at least two points of time.
Claim 23
Independent Claim
88 words
A method of producing a distribution of temperature of a living body comprising the following steps of: attaining data representing a cross-sectional image of a living body; discriminating boundaries of different textures of the living body in the cross-sectional image; and estimating in association with the attained cross-sectional image, based on an intensity of an electric field applied to the living body and parameters of the living body respectively preset for the textures, a temperature distribution of the living body generated due to the electric field applied thereto.
Claim 24
Independent Claim
88 words
A method of producing a distribution of temperature of a living body comprising the following steps of: attaining data representing a cross-sectional image of a living body; discriminating boundaries of different textures of the living body in the cross-sectional image; and estimating in association with the attained cross-sectional image, based on an intensity of an electric field applied to the living body and parameters of the living body respectively preset for the textures, a temperature distribution of the living body generated due to the electric field applied thereto.
Claim 25
Dependent Claim
32 words
A method in accordance with claim 19 wherein said step of discriminating the boundaries includes a step of conducting an image processing on the cross-sectional image to extract contours of the textures.
Claim 26
Dependent Claim
25 words
A method in accordance with claim 19 wherein said step of discriminating the boundaries includes a step of inputting data representing contours of the textures.
Claim 27
Dependent Claim
41 words
A method in accordance with claim 19 further including the steps of: measuring a temperature of a predetermined position of the living body; and correcting the parameters of the living body based on a temperature actually measured and an estimated temperature.
Claim 28
Dependent Claim
31 words
A method according to claim 22 wherein said step of correcting the parameters of the living body is achieved such that a difference between the measured and estimated temperatures is minimized.
Claim 29
Dependent Claim
48 words
A method according to claim 23 wherein said step of correcting the parameters of the living body is conducted depending on the parameters of the living body employed by said temperature distribution estimation step and the measured and estimated temperatures associated with at least two points of time.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1996-07-05 | 1997-01-04 | 1997-07-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-07-05 | 2001-01-04 | 2001-07-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-07-05 | 2005-01-04 | 2005-07-06 | $7700.00 | Window Closed / Lapsed |