US5239119A
Expired / Lapsed
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Catalytic synthesis of azines from H2 O2 /NH3 /carbonyl compounds
Assignee: Arkema France SA
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Filing: 1991-11-25
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Granted: 1993-08-24
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Expires: 2011-11-25
Abstract
Abstract Azines are synthesized from aqueous hydrogen peroxide, ammonia and a carbonyl compound, e.g., acetone, methyl ethyl ketone or methyl isobutyl ketone, in the presence of a catalytically effective amount of immixture of an amide of a weak acid and an ammonium salt corresponding to such weak acid. A more general high output such process comprises (a) interreacting aqueous hydrogen peroxide, ammonia and a carbonyl compound in the presence of a catalytically effective amount of immixture comprising an amide of a weak acid, (b) separating the azine thus produced from the medium of reaction, (c) reconstituting the amount of the amide in the medium of reaction to the initial amount thereof present at the onset of step (a), and (d) recycling such reconstituted medium of reaction to step (a).
Inventors
- 👤 Jean-Pierre Schirmann
- 👤 Pierre Tellier
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 01:00
CPC Classifications
C; C07; C07C; C07C241/00; C07C249/00; C07C249/16
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
57 words
A process for the preparation of an azine, comprising interreacting aqueous hydrogen peroxide, ammonia and a carbonyl compound in the presence of a catalytically effective amount of immixture consisting essentially of an amide of a weak acid and the ammonium salt corresponding to such acid, and thereafter separating the azine thus produced from the medium of reaction.
Claim 2
Dependent Claim
57 words
A process for the preparation of an azine, comprising interreacting aqueous hydrogen peroxide, ammonia and a carbonyl compound in the presence of a catalytically effective amount of immixture consisting essentially of an amide of a weak acid and the ammonium salt corresponding to such acid, and thereafter separating the azine thus produced from the medium of reaction.
Claim 3
Dependent Claim
120 words
The process as defined by claim 1, said carbonyl compound having the formula: ##STR5## in which R 1 and R 2 , which may be identical or different, are each hydrogen, an alkyl radical having from 1 to 12 carbon atoms, a branched alkyl or cycloalkyl radical having from 3 to 12 carbon atoms, or an aromatic radical having from 6 to 12 carbon atoms, with the proviso that R 1 and R 2 may together form a linear or branched alkylene radical having from 3 to 12 carbon atoms, and with the further proviso that such radicals R 1 and R 2 may be substituted by at least one halogen, NO 2 , hydroxyl, alkoxy or carboxylic ester group.
Claim 4
Dependent Claim
24 words
The process as defined by claim 2, said carbonyl compound comprising formaldehyde, acetaldehyde, butyraldehyde, isobutyraldehyde, n-pentanal, pivalaldehyde, benzaldehyde, monochlorobenzaldehydes, paranitrobenzaldehyde, anisaldehyde, beta-chloropropionaldehyde or beta-methoxyproprionaldehyde.
Claim 5
Dependent Claim
32 words
The process as defined by claim 2, said carbonyl compound comprising acetone, 2-pentanone, 3-pentanone, methyl isopropyl ketone, methyl isobutyl ketone, methyl ethyl ketone, methyl cyclohexyl ketone, acetophenone, benzophenone, cyclobutanone, cyclopentanone or cyclohexanone.
Claim 6
Dependent Claim
19 words
The process as defined by claim 2, said carbonyl compound comprising acetone, methyl ethyl ketone or methyl isobutyl ketone.
Claim 7
Dependent Claim
30 words
The process as defined by claim 1, comprising interreacting 0.2 to 5 moles of said carbonyl compound and 0.1 to 10 moles of ammonia per mole of aqueous hydrogen peroxide.
Claim 8
Dependent Claim
23 words
The process as defined by claim 1, said amide of a weak acid having a dissociation constant of less than 5×10 -5 .
Claim 9
Dependent Claim
19 words
The process as defined by claim 7, said amide of a weak acid comprising acetamide, propionamide, n-butyramide or isobutyramide.
Claim 10
Dependent Claim
28 words
The process as defined by claim 1, said immixture comprising 1 to 25 parts by weight of said ammonium salt per 5 parts by weight of said amide.
Claim 11
Dependent Claim
16 words
The process as defined by claim 1, wherein the medium of reaction further comprises an alcohol.
Claim 12
Dependent Claim
96 words
A process for the preparation of an azine, comprising (a) interreacting aqueous hydrogen peroxide, ammonia and a carbonyl compound in the presence of a catalytically effective amount of immixture comprising an amide of a weak acid, (b) separating the azine thus produced from the medium of reaction, (c) reconstituting the amount of said amide in the medium of reaction to the initial amount thereof present at the onset of step (a) by regenerating said amide from ammonium salt generated during the reaction of step (a), and (d) recycling such reconstituted medium of reaction to step (a).
Claim 13
Dependent Claim
96 words
A process for the preparation of an azine, comprising (a) interreacting aqueous hydrogen peroxide, ammonia and a carbonyl compound in the presence of a catalytically effective amount of immixture comprising an amide of a weak acid, (b) separating the azine thus produced from the medium of reaction, (c) reconstituting the amount of said amide in the medium of reaction to the initial amount thereof present at the onset of step (a) by regenerating said amide from ammonium salt generated during the reaction of step (a), and (d) recycling such reconstituted medium of reaction to step (a).
Claim 14
Dependent Claim
18 words
The process as defined by claim 11, said immixture comprising an ammonium salt corresponding to said weak acid.
Claim 15
Dependent Claim
13 words
The process as defined by claim 11, said immixture comprising a co-catalyst compound.
Claim 16
Dependent Claim
31 words
The process of claim 11, wherein said amide is regenerated by heating the medium of reaction to a temperature sufficient to achieve reversion of said ammonium salt back to said amide.
Claim 17
Dependent Claim
21 words
The process of claim 11, wherein an excess of ammonia is added to the reconstituted medium of reaction prior to recycling.
Claim 18
Dependent Claim
29 words
The process of claim 11, wherein said reconstituting of said amide is completed on a portion of said reaction medium, said portion being less than the entire reaction medium.
Claim 19
Dependent Claim
26 words
The process of claim 11, further comprising removing high-boiling impurities at the end of step (c) by distillation or passing the solution over absorbent microporous particles.
References Cited (Backward Citations)
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