US5256372A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Dipstick test device including a removable filter assembly
Assignee: Idexx Laboratories Inc
•
Filing: 1989-12-05
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Granted: 1993-10-26
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Expires: 2009-12-05
Abstract
Abstract Disclosed is a dipstick test device for detecting an analyte in a liquid sample by treating the analyte with at least one liquid reagent to form a detectable reaction product. The device includes: a) an aqueous impermeable, aqueous insoluble reaction zone, adapted to retain the detectable reaction product; and b) a control absorbent above, and in liquid-transferring relation with, the reaction zone. The control absorbent has a predetermined, limited liquid-absorbing capacity, and the dipstick is sized and configured for insertion into a vessel containing the sample, with the control absorbent oriented above the reaction zone, so that the control absorbent fills to capacity with sample and the reaction zone incubates with the sample. The device may further include an absorbent reservoir which can be moved into liquid transferring contact with the reaction zone.
Inventors
- 👤 Paul C. Brooks
- 👤 Erwin F. Workman
- 👤 Quentin J. Tonelli
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 23:24
CPC Classifications
B; B01; B01L; B01L3/00; B01L3/50; B01L3/502; B01L3/5029; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/543; G01N33/54366; B01L2300/00; B01L2300/08; B01L2300/0809; B01L2300/0832; B01L2400/00; B01L2400/04; B01L2400/0403; B01L2400/0406; Y; Y10; Y10S; Y10S436/00; Y10S436/805; Y10S436/807; Y10S436/81; Y10T; Y10T436/00; Y10T436/25; Y10T436/25375; Y10T436/255
Claims Analysis
Total Claims: 20
Claim 1
Independent Claim
158 words
A dipstick test device for detecting an analyte in a liquid sample by treating the analyte with at least one liquid reagent to form a detectable reaction product, said dipstick of said test device comprising: a) means defining an aqueous permeable, aqueous insoluble reaction zone, positioned at one end of an elongated dipstick and adapted to retain said detectable reaction product; b) a control absorbent in liquid-transferring relation with the means defining the reaction zone, said control absorbent having a predetermined, limited liquid-absorbing capacity, said dipstick being sized and configured for insertion into a vessel containing said sample, whereby said control absorbent fills to capacity with sample and said means defining a reaction zone incubates with said sample; c) a re-movable filter assembly positioned at said end of said dipstick; and d) a reaction tray comprising a well adapted to receive said filter assembly on said dipstick and to retain said filter assembly as said dipstick is removed.
Claim 2
Dependent Claim
158 words
A dipstick test device for detecting an analyte in a liquid sample by treating the analyte with at least one liquid reagent to form a detectable reaction product, said dipstick of said test device comprising: a) means defining an aqueous permeable, aqueous insoluble reaction zone, positioned at one end of an elongated dipstick and adapted to retain said detectable reaction product; b) a control absorbent in liquid-transferring relation with the means defining the reaction zone, said control absorbent having a predetermined, limited liquid-absorbing capacity, said dipstick being sized and configured for insertion into a vessel containing said sample, whereby said control absorbent fills to capacity with sample and said means defining a reaction zone incubates with said sample; c) a re-movable filter assembly positioned at said end of said dipstick; and d) a reaction tray comprising a well adapted to receive said filter assembly on said dipstick and to retain said filter assembly as said dipstick is removed.
Claim 3
Dependent Claim
65 words
The test device of claim 1, said test device further comprising: e) an absorbent reservoir; f) means retaining said absorbent reservoir in a first position above and spaced apart from liquid-transferring relationship with said means defining said reaction zone; and g) means for moving said absorbent reservoir from said first position to a second position in liquid-transferring relationship with the means defining said reaction zone.
Claim 4
Dependent Claim
45 words
The test device of claim 2, wherein said means defining a reaction zone is contained in a test head, and said absorbent reservoir is concentrically positioned with respect to said test head, allowing telescoping movement of said absorbent reservoir with respect to said test head.
Claim 5
Dependent Claim
25 words
The test device of claim 2 wherein said means for moving said absorbent reservoir comprises an activator that is recessed from the external dipstick profile.
Claim 6
Dependent Claim
141 words
The test device of claim 1 or claim 2 wherein said control absorbent is positioned above said means defining a reaction zone, said device further comprising a sample well, said means defining a reaction zone being positioned in said dipstick so that when the dipstick is inserted in the sample well containing a predetermined volume of sample, a first side of the means defining the reaction zone contacts the sample, and a second side of the means defining a reaction zone, which is opposite said first side, and is maintained in liquid transferring relationship with said control absorbent, said control absorbent having an absorption capacity less than said predetermined sample volume, whereby both said first and said seocnd sides of said means defining a reaction zone are incubated with said volume of sample when said dipstick is inserted in said well.
Claim 7
Dependent Claim
28 words
The device of claim 5 wherein said first side of said means defining a reaction zone and said second side thereof are opposite surfaces of a flat member.
Claim 8
Dependent Claim
29 words
The device of claim 1 or claim 2 wherein said means defining a reaction zone comprises at least one reactant participating in a reaction to form said detectable product.
Claim 9
Dependent Claim
38 words
The device of claim 1 or claim 2 wherein said reaction product is detected by visual inspection after said filter assembly is removed and said means defining a reaction zone is visible by external inspection of said device.
Claim 10
Dependent Claim
35 words
The device of claim 8 further comprising a means defining a contrast region surrounding said reaction zone to aid in said detection by contrasting with said reaction zone in respect to a characteristic being assayed.
Claim 11
Dependent Claim
16 words
The device of claim 9 further comprising an intensity scale for quantitive detection of sample analyte.
Claim 12
Dependent Claim
22 words
The test device of claim 1 or claim 2 wherein said means defining a reaction zone is integral with said control absorbent.
Claim 13
Dependent Claim
25 words
The test device of claim 1 or claim 2 wherein said means defining a reaction zone is attached to a face of said control absorbent.
Claim 14
Dependent Claim
36 words
The test device of claim 1 or claim 2 wherein said means defining a reaction zone defines at least two reaction regions and said test device comprises means for isolating said reaction regions from each other.
Claim 15
Dependent Claim
18 words
The test device of claim 13 wherein at least one of said reaction regions is a control region.
Claim 16
Dependent Claim
32 words
The test device of claim 1 or claim 2 further comprising an aqueous impermeable face plate having at least one opening to allow liquid to reach said means defining a reaction zone.
Claim 17
Dependent Claim
32 words
The test device of claim 15 wherein said means defining a reaction zone comprises a flat reagent retention element having a protrusion positioned to extending into an opening in said face plate.
Claim 18
Dependent Claim
33 words
The test device of claim 15 wherein said control absorbent is shaped to present a node that forces said means defining a reaction zone to protrude into an opening in said face plate.
Claim 19
Dependent Claim
27 words
The test device of claim 1 or claim 2 further comprising a reagent pack sized and configured to supply a plurality of reagents to said reaction zone.
Claim 20
Dependent Claim
24 words
The test device of claim 1 or claim 2 wherein said means defining a reaction zone comprises a specific binding partner for said analyte.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1996-10-25 | 1997-04-26 | 1997-10-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-10-25 | 2001-04-26 | 2001-10-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-10-25 | 2005-04-26 | 2005-10-26 | $7700.00 | Window Closed / Lapsed |