← Back to Patent Explorer
US5299579A Expired / Lapsed US ⏱️ 0.0 years remaining

Apparatus for examining a patient's pulmonary function

Assignee: MINCO AB
•
Filing: 1990-11-23
•
Granted: 1994-04-05
•
Expires: 2010-11-23
📄 Original PDF 🌐 Google Patents 🔄 Sync Now

Abstract

Abstract Apparatus for examining pulmonary function parameters of a patient comprises a rebreathing system (1-6) adapted to be connected with the patient and including a variable-volume reservoir (1), a carbon dioxide absorber (19) in an inhalation conduit (3) and valve means (24) for selectively switching the carbon dioxide absorber (19) on and off. A carbon dioxide meter (25) is controllable to selectively measure the carbon dioxide content of respiratory gas being exhaled and of exhaled respiratory gas collected in the reservoir (1). Volume monitoring devices (17,18) monitory the volume variations of the reservoir (1). A computing unit (30) computes the pulmonary blood flow and other pulmonary function parameters using carbon dioxide concentration parameters measured by the carbon dioxide meter (25) and ventilatory rate parameters are measured by the monitoring devices (17,18).

Inventors

  • 👤 Andras Gedeon
  • 👤 Claes Mebius

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-06 14:16
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/08; A61B5/083; A61M; A61M16/00; A61M16/0057; A61M16/0081; A61M16/22; A61M16/10; A61M16/1005; A61M2016/102; A61M2016/103; A61M2205/00; A61M2205/33; A61M2205/3379; A61M2205/3389; A61M2230/00; A61M2230/40; A61M2230/43; A61M2230/432; G; G16; G16H; G16H20/00; G16H20/40; G16H50/00; G16H50/20

Claims Analysis

Total Claims: 21
Claim 1
Independent Claim 410 words
Apparatus for examining and measuring the pulmonary function of a patient, comprising (a) a sealed reservoir (1) having an interior of variable volume, (b) an inhalation conduit (3) and an exhalation conduit (2), which are connected with the reservoir (1) and include one-way valve means (5,6) permitting flow of gas through the inhalation conduit only in the direction from the reservoir and permitting flow of gas through the exhalation conduit only in the direction toward the reservoir, (c) first connecting means (4) for connecting the inhalation conduit (3) and the exhalation conduit (2) with the respiratory tract of a patient to be examined, such that the patient can inhale from the reservoir (1) through the inhalation conduit and exhale into the reservoir through the exhalation conduit, (d) carbon dioxide adsorbing means (19) for removing carbon dioxide from a stream of gas flowing through the inhalation conduit (3), (e) monitoring means (17,18) for monitoring volumetric variations of the reservoir (1) resulting from the inhalation and exhalation of the patient and for determining the patient's total ventilatory rate, characterized by means (24) for selectively switching the carbon dioxide absorbing means (19) into the inhalation conduit (3), concentration measuring means (25) for measuring the carbon dioxide concentration of a gas mixture, second connecting means (26) for connecting the concentration measuring means (25) with the interior of the reservoir (1) and with the first connecting means (4), and a computing unit (3) which is connected with the concentration measuring means (25) and with the monitoring means (17,18) and which comprises computing means for computing the pulmonary blood flow Q p of the patient essentially in accordance with the equation ##EQU9## wherein MV is the patient's total ventilatory rate, P aCO2 is the carbon dioxide concentration in the reservoir (1) at equilibrium, when the patient inhales from and exhales into the reservoir (10 with the carbon dioxide absorbing means (19) switched into the inhalation conduit (3), P etCO2 is the carbon dioxide concentration of the gas exhaled by the patient at the end of an exhalation with the carbon dioxide absorbing means (19) switched into the inhalation conduit (3), P AstCO2 is the asymptotic value which the carbon dioxide concentration of the gas exhaled by the patient approaches at the end of each exhalation when the patient inhales from and exhales into the reservoir (1) with the carbon dioxide absorbing means (19) disconnected from the inhalation conduit (3), and S c is a known constant.
Claim 2
Dependent Claim 410 words
Apparatus for examining and measuring the pulmonary function of a patient, comprising (a) a sealed reservoir (1) having an interior of variable volume, (b) an inhalation conduit (3) and an exhalation conduit (2), which are connected with the reservoir (1) and include one-way valve means (5,6) permitting flow of gas through the inhalation conduit only in the direction from the reservoir and permitting flow of gas through the exhalation conduit only in the direction toward the reservoir, (c) first connecting means (4) for connecting the inhalation conduit (3) and the exhalation conduit (2) with the respiratory tract of a patient to be examined, such that the patient can inhale from the reservoir (1) through the inhalation conduit and exhale into the reservoir through the exhalation conduit, (d) carbon dioxide adsorbing means (19) for removing carbon dioxide from a stream of gas flowing through the inhalation conduit (3), (e) monitoring means (17,18) for monitoring volumetric variations of the reservoir (1) resulting from the inhalation and exhalation of the patient and for determining the patient's total ventilatory rate, characterized by means (24) for selectively switching the carbon dioxide absorbing means (19) into the inhalation conduit (3), concentration measuring means (25) for measuring the carbon dioxide concentration of a gas mixture, second connecting means (26) for connecting the concentration measuring means (25) with the interior of the reservoir (1) and with the first connecting means (4), and a computing unit (3) which is connected with the concentration measuring means (25) and with the monitoring means (17,18) and which comprises computing means for computing the pulmonary blood flow Q p of the patient essentially in accordance with the equation ##EQU9## wherein MV is the patient's total ventilatory rate, P aCO2 is the carbon dioxide concentration in the reservoir (1) at equilibrium, when the patient inhales from and exhales into the reservoir (10 with the carbon dioxide absorbing means (19) switched into the inhalation conduit (3), P etCO2 is the carbon dioxide concentration of the gas exhaled by the patient at the end of an exhalation with the carbon dioxide absorbing means (19) switched into the inhalation conduit (3), P AstCO2 is the asymptotic value which the carbon dioxide concentration of the gas exhaled by the patient approaches at the end of each exhalation when the patient inhales from and exhales into the reservoir (1) with the carbon dioxide absorbing means (19) disconnected from the inhalation conduit (3), and S c is a known constant.
Claim 3
Dependent Claim 32 words
Apparatus according to claim 1, characterized in that the concentration measuring means (25) is selectively and alternatively connectable with the interior of the reservoir (1) and with the first connecting means (4).
Claim 4
Dependent Claim 36 words
Apparatus according to claim 2, characterized in that the computing unit (30) comprises means for computing a carbon dioxide removal V CO2 from the patient's lungs essentially in accordance with the equation V.sub.CO2 =P.sub.eCO2 ×MV (1)
Claim 5
Dependent Claim 75 words
Apparatus according to claim 3, characterized in that the computing unit (30) comprises means for computing the patient's pulmonary volume LV for carbon dioxide essentially in accordance with the equation ##EQU10## wherein T is a time constant for the exponential increase of P etCO2 when the patient inhales from and exhales into the reservoir (1) with the carbon dioxide absorbing means (19) disconnected from the inhalation conduit (3), and P B is the atmospheric pressure.
Claim 6
Dependent Claim 68 words
Apparatus according to claim 4, characterized in that it comprises means (8,9,10) controlled by the monitoring means (17,18) for feeding pure oxygen to the reservoir (1) in such quantities that the reservoir volume is substantially the same at a given point in each breathing cycle of the patient, and means (18) for measuring a quantity V O2 of oxygen fed to the reservoir (1) per unit of time.
Claim 7
Dependent Claim 68 words
Apparatus according to claim 3, characterized in that it comprises means (8,9,10) controlled by the monitoring means (17,18) for feeding pure oxygen to the reservoir (1) in such quantities that the reservoir volume is substantially the same at a given point in each breathing cycle of the patient, and means (18) for measuring a quantity V O2 of oxygen fed to the reservoir (1) per unit of time.
Claim 8
Dependent Claim 75 words
Apparatus according to claim 6, characterized in that it additionally comprises an outer rigid fixed-volume casing (13) sealingly enclosing the reservoir (1), a connecting conduit (14) for constantly connecting an interior of the rigid casing with respirator (23) inhalation and exhalation conduits (21,22) respectively discharging and receiving respiratory gas, and a connecting conduit (11) comprising shut-off means (12) for connecting the interior of the reservoir (1) with the respirator (23) inhalation and exhalation conduits (21,22).
Claim 9
Dependent Claim 75 words
Apparatus according to claim 2, characterized in that the computing unit (30) comprises areas for computing the patient's pulmonary volume LV for carbon dioxide essentially in accordance with the equation ##EQU11## wherein T is a time constant for the exponential increase of P etCO2 when the patient inhales from and exhales into the reservoir (1) with the carbon dioxide absorbing means (19) disconnected from the inhalation conduit (3), and P B is the atmospheric pressure.
Claim 10
Dependent Claim 68 words
Apparatus according to claim 8, characterized in that it comprises means (8,9,1) controlled by the monitoring means (17,18) for feeding pure oxygen to the reservoir (1) in such quantities that the reservoir volume is substantially the same at a given point in each breathing cycle of the patient, and means (18) for measuring a quantity V O2 of oxygen fed to the reservoir (1) per unit of time.
Claim 11
Dependent Claim 68 words
Apparatus according to claim 2, characterized in that it comprises means (8,9,10) controlled by the monitoring means (17,18) for feeding pure oxygen to the reservoir (1) in such quantities that the reservoir volume is substantially the same at a given point in each breathing cycle of the patient, and means (18) for measuring a quantity V O2 of oxygen fed to the reservoir (1) per unit of time.
Claim 12
Dependent Claim 27 words
Apparatus according to claim 5, characterized in that the computing unit (30) comprises means for computing a respiratory quotient RQ substantially in accordance with the equation ##EQU12##
Claim 13
Dependent Claim 56 words
Apparatus according to claim 11, characterized in that the computing unit (30) comprises means to compute oxygen saturation of mixed venous blood of the patient substantially in accordance with the equation ##EQU13## wherein Hb is the patient's hemoglobin concentration and the oxygen saturation of arterial blood is presupposed to be 98 percent for a healthy person.
Claim 14
Dependent Claim 75 words
Apparatus according to claim 12, characterized in that it additionally comprises an outer rigid fixed-volume casing (13) sealingly enclosing the reservoir (1), a connecting conduit (14) for constantly connecting an interior of the rigid casing with respirator (23) inhalation and exhalation conduits (21,22) respectively discharging and receiving respiratory gas, and a connecting conduit (11) comprising shut-off means (12) for connecting the interior of the reservoir (1) with the respirator (23) inhalation and exhalation conduits (21,22).
Claim 15
Dependent Claim 44 words
Apparatus according to claim 11, characterized in that the computing unit (30) comprises means to compute cardiac output Q of the patient substantially in accordance with the equation ##EQU14## wherein S aO2 is oxygen saturation of arterial blood of the patient as measured separately.
Claim 16
Dependent Claim 75 words
Apparatus according to claim 14, characterized in that it additionally comprises an outer rigid fixed-volume casing (13) sealingly enclosing the reservoir (1), a connecting conduit (14) for constantly connecting an interior of the rigid casing with respirator (23) inhalation and exhalation conduits (21,22) respectively discharging and receiving respiratory gas, and a connecting conduit (11) comprising shut-off means (12) for connecting the interior of the reservoir (1) with the respirator (23) inhalation and exhalation conduits (21,22).
Claim 17
Dependent Claim 56 words
Apparatus according to claim 10, characterized in that the computing unit (30) comprises means to compute oxygen saturation of mixed venous blood of the patient substantially in accordance with the equation ##EQU15## wherein Hb is the patient's hemoglobin concentration and the oxygen saturation of arterial blood is presupposed to be 98 percent for a healthy person.
Claim 18
Dependent Claim 44 words
Apparatus according to claim 16, characterized in that the computing unit (30) comprises means to compute cardiac output Q of the patient substantially in accordance with the equation ##EQU16## wherein S aO2 is oxygen saturation of arterial blood of the patient as measured separately.
Claim 19
Dependent Claim 44 words
Apparatus according to claim 10, characterized in that the computing unit (30) comprises means to compute cardiac output Q of the patient substantially in accordance with the equation ##EQU17## wherein S aO2 is oxygen saturation of arterial blood of the patient as measured separately.
Claim 20
Dependent Claim 75 words
Apparatus according to claim 2, characterized in that it additionally comprises an outer rigid fixed-volume casing (13) sealingly enclosing the reservoir (1), a connecting conduit (14) for constantly connecting an interior of the rigid casing with respirator (23) inhalation and exhalation conduits (21,22) respectively discharging and receiving respiratory gas, and a connecting conduit (11) comprising shut-off means (12) for connecting the interior of the reservoir (1) with the respirator (23) inhalation and exhalation conduits (21,22).
Claim 21
Dependent Claim 75 words
Apparatus according to claim 1, characterized in that it additionally comprises an outer rigid fixed-volume casing (13) sealingly enclosing the reservoir (1), a connecting conduit (14) for constantly connecting an interior of the rigid casing with respirator (23) inhalation and exhalation conduits (21,22) respectively discharging and receiving respiratory gas, and a connecting conduit (11) comprising shut-off means (12) for connecting the interior of the reservoir (1) with the respirator (23) inhalation and exhalation conduits (21,22).

References Cited (Backward Citations)

US2592694A Cited
US3527205A Cited
DE2425535A1 Cited
US3951137A Cited
US4231362A Cited
US4233842A Cited
US4856531A Cited
US4753245A Cited
US4947860A Cited
US5038772A Cited
US5111809A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1997-04-04 1997-10-04 1998-04-05 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2001-04-04 2001-10-04 2002-04-05 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2005-04-04 2005-10-04 2006-04-05 $7700.00 Window Closed / Lapsed

Assigned Categories & Tags

No categories assigned to this patent yet.

Assign Category Tag