US5318595A
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Pacing method and system for blood flow velocity measurement and regulation of heart stimulating signals based on blood flow velocity
Assignee: Individual
•
Filing: 1992-05-08
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Granted: 1994-06-07
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Expires: 2012-05-08
Abstract
Abstract A system and method for regulation of pacing signals, and more particularly for regulation of an atrioventricular interval in a cardiac electrotherapy system based on measurement of blood flow velocity profiles. More particularly, a diastolic blood flow filling wave and an atrial blood flow filling wave are determined and a time delay between peaks of the two waves and/or a superimposition velocity of the two waves relative to one another are utilized for the regulation. The regulation preferably occurs by comparing the measured time delay to a desired time delay or desired superimposition velocity, and the result of the comparison is then employed for regulating the pacing, or regulating the atrio-ventricular interval.
Inventors
- 👤 Bozidar Ferek-Petric
- 👤 Branko Breyer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 11:57
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/18; A61N1/32; A61N1/36; A61N1/362; A61N1/365; A61N1/36514; A61N1/36571; A61N1/36528
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
94 words
A system for regulating an atrio-ventricular (A-V) interval in a cardiac electrotherapy system, comprising: flow velocity measurement means for measuring blood flow velocity at a region of a valve between an atrial chamber and a ventricular chamber to determine a diastolic blood flow velocity filling wave (E wave) and an atrial blood flow velocity filling wave (A wave); means for determining a time interval (EA interval) between the diastolic blood flow filling wave and the atrial blood flow filling wave; and means for regulating the atrio-ventricular (A-V) interval based on the measured EA interval.
Claim 2
Independent Claim
94 words
A system for regulating an atrio-ventricular (A-V) interval in a cardiac electrotherapy system, comprising: flow velocity measurement means for measuring blood flow velocity at a region of a valve between an atrial chamber and a ventricular chamber to determine a diastolic blood flow velocity filling wave (E wave) and an atrial blood flow velocity filling wave (A wave); means for determining a time interval (EA interval) between the diastolic blood flow filling wave and the atrial blood flow filling wave; and means for regulating the atrio-ventricular (A-V) interval based on the measured EA interval.
Claim 3
Dependent Claim
29 words
A system according to claim 1 including means for comparing the measured EA interval to a desired EA interval, and based on the comparison, for regulating the A-V interval.
Claim 4
Dependent Claim
36 words
A system according to claim 1 including means for measuring a superimposition velocity where the E filling wave joins the A filling wave and for utilizing the measured superimposition velocity for regulation of the A-V interval.
Claim 5
Independent Claim
103 words
A system for regulating an atrio-ventricular (A-V) interval in a cardiac electrotherapy system, comprising: flow velocity measurement means for measuring blood flow velocity at a region of a valve between an atrial chamber and a ventricular chamber for determining a diastolic blood flow velocity filling wave (E wave) and an atrial blood flow velocity filling wave (A wave); means for determining a time interval (EA interval) between the diastolic blood flow filling wave and the atrial blood flow filling wave; means for generating pacing signals to the heart; and means for employing the EA interval when regulating the pacing signals to the heart.
Claim 6
Independent Claim
103 words
A system for regulating an atrio-ventricular (A-V) interval in a cardiac electrotherapy system, comprising: flow velocity measurement means for measuring blood flow velocity at a region of a valve between an atrial chamber and a ventricular chamber for determining a diastolic blood flow velocity filling wave (E wave) and an atrial blood flow velocity filling wave (A wave); means for determining a time interval (EA interval) between the diastolic blood flow filling wave and the atrial blood flow filling wave; means for generating pacing signals to the heart; and means for employing the EA interval when regulating the pacing signals to the heart.
Claim 7
Independent Claim
86 words
A method for regulating an atrio-ventricular (A-V) interval in a cardiac electrotherapy system, comprising the steps of: determining a diastolic blood flow velocity filling wave (E wave) and an atrial blood flow velocity filling wave (A wave) at a region of a valve between an atrial chamber and a ventricular chamber; determining a time interval (EA interval) between the diastolic blood flow filling wave and the atrial blood flow filling wave; and regulating the atrio-ventricular (A-V) interval based on the measured EA interval for cardiac electrotherapy.
Claim 8
Independent Claim
86 words
A method for regulating an atrio-ventricular (A-V) interval in a cardiac electrotherapy system, comprising the steps of: determining a diastolic blood flow velocity filling wave (E wave) and an atrial blood flow velocity filling wave (A wave) at a region of a valve between an atrial chamber and a ventricular chamber; determining a time interval (EA interval) between the diastolic blood flow filling wave and the atrial blood flow filling wave; and regulating the atrio-ventricular (A-V) interval based on the measured EA interval for cardiac electrotherapy.
Claim 9
Independent Claim
90 words
A method for regulating an atrio-ventricular (A-V) interval in a cardiac electrotherapy system, comprising the steps of: determining a diastolic blood flow velocity filling wave (E wave) and an atrial blood flow velocity filling wave (A wave) at a region of a valve between an atrial chamber and a ventricular chamber; determining a time interval (EA interval) between the diastolic blood flow filling wave and the atrial blood flow filling wave; generating pacing signals to the heart; and employing the EA interval to regulate the pacing signals to the heart.
Claim 10
Independent Claim
90 words
A method for regulating an atrio-ventricular (A-V) interval in a cardiac electrotherapy system, comprising the steps of: determining a diastolic blood flow velocity filling wave (E wave) and an atrial blood flow velocity filling wave (A wave) at a region of a valve between an atrial chamber and a ventricular chamber; determining a time interval (EA interval) between the diastolic blood flow filling wave and the atrial blood flow filling wave; generating pacing signals to the heart; and employing the EA interval to regulate the pacing signals to the heart.
Claim 11
Dependent Claim
86 words
A cardiac electrotherapy system, comprising: flow velocity measurement means for determining a diastolic blood flow velocity filling wave (E-wave) and an atrial blood flow velocity filling wave (A-wave) at a region of a valve between an atrial chamber and a ventricular chamber; means for determining a parameter indicating a relationship between the diastolic blood flow filling wave and the atrial blood flow filling wave; means for generating stimulating signals to the heart; and means for regulating the stimulating signals to the heart based on said parameter.
Claim 12
Dependent Claim
86 words
A cardiac electrotherapy system, comprising: flow velocity measurement means for determining a diastolic blood flow velocity filling wave (E-wave) and an atrial blood flow velocity filling wave (A-wave) at a region of a valve between an atrial chamber and a ventricular chamber; means for determining a parameter indicating a relationship between the diastolic blood flow filling wave and the atrial blood flow filling wave; means for generating stimulating signals to the heart; and means for regulating the stimulating signals to the heart based on said parameter.
Claim 13
Dependent Claim
27 words
A system according to claim 7 wherein said parameter comprises a time interval between the diastolic blood flow filling wave and the atrial blood flow filling wave.
Claim 14
Dependent Claim
24 words
A system according to claim 7 wherein said parameter comprises a superimposition velocity at which the diastolic filling wave meets the atrial filling wave.
Claim 15
Independent Claim
78 words
A method for cardiac electrotherapy comprising the steps of: determining a diastolic blood flow velocity filling wave (E-wave) and an atrial blood flow velocity filling wave (A-wave) at a region of a valve between an atrial chamber and a ventricular chamber; determining a parameter indicating a relationship between the diastolic blood flow filling wave and the atrial blood flow filling wave; generating stimulating signals to the heart; and regulating stimulating signals to the heart based on said parameter.
Claim 16
Independent Claim
78 words
A method for cardiac electrotherapy comprising the steps of: determining a diastolic blood flow velocity filling wave (E-wave) and an atrial blood flow velocity filling wave (A-wave) at a region of a valve between an atrial chamber and a ventricular chamber; determining a parameter indicating a relationship between the diastolic blood flow filling wave and the atrial blood flow filling wave; generating stimulating signals to the heart; and regulating stimulating signals to the heart based on said parameter.
Claim 17
Dependent Claim
27 words
A method according to claim 10 wherein said parameter comprises a time interval between the diastolic blood flow filling wave and the atrial blood flow filling wave.
Claim 18
Dependent Claim
24 words
A method according to claim 10 wherein said parameter comprises a superimposition velocity at which the diastolic filling wave meets the atrial filling wave.
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| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 1997-06-06 | 1997-12-06 | 1998-06-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-06-06 | 2001-12-06 | 2002-06-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-06-06 | 2005-12-06 | 2006-06-07 | $7700.00 | Window Closed / Lapsed |