US5420145A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Carboxylic acid derivative
Assignee: Shionogi and Co Ltd
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Filing: 1993-03-23
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Granted: 1995-05-30
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Expires: 2013-03-23
Abstract
Abstract Carboxylic acid derivatives having potent retinoid-type pharmacological activities are disclosed. The compounds disclosed are represented by the following formula: ##STR1## wherein R 1 , R 2 , and R 3 independently represent a hydrogen atom or an alkyl group with the exception that all of R 1 , R 2 , and R 3 do not simultaneously represent hydrogen atoms and R 1 together with R 2 optionally represent a cyclic structure formed by the combination thereof; R 4 represents a hydrogen atom or an alkyl group; X represents a nitrogen atom or C--OH; and A represents --CO--NH-- or --NH--CO--.
Inventors
- 👤 Koichi Shudo
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 18:23
CPC Classifications
C; C07; C07D; C07D213/00; C07D213/02; C07D213/04; C07D213/60; C07D213/78; C07D213/79; C07C; C07C233/00; C07C233/64; C07C233/81; C07C233/82; C07C233/87; C07D213/80; C07C2602/00; C07C2602/02; C07C2602/04; C07C2602/10
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
87 words
A carboxylic acid compound represented by the following formula: ##STR3## wherein R 1 , R 2 , and R 3 independently represent a hydrogen atom or an alkyl group of at least two carbon atoms wherein at least two of R 1 , R 2 , and R 3 represent an alkyl group of at least two carbon atoms; R 4 represents a hydrogen atom or an alkyl group; A represents --CO--NH-- or --NH--CO--; and wherein A is in a para position relative to COOR 4 .
Claim 2
Dependent Claim
87 words
A carboxylic acid compound represented by the following formula: ##STR3## wherein R 1 , R 2 , and R 3 independently represent a hydrogen atom or an alkyl group of at least two carbon atoms wherein at least two of R 1 , R 2 , and R 3 represent an alkyl group of at least two carbon atoms; R 4 represents a hydrogen atom or an alkyl group; A represents --CO--NH-- or --NH--CO--; and wherein A is in a para position relative to COOR 4 .
Claim 3
Dependent Claim
101 words
A pharmaceutical composition comprising an effective amount of a carboxylic acid compound represented by the following formula: ##STR4## wherein R 1 , R 2 , and R 3 independently represent a hydrogen atom or an alkyl group of at least two carbon atoms wherein at least two of R.sup., R 2 , and R 3 represent an alkyl group of at least two carbon atoms; R 4 represents a hydrogen atom or an alkyl group; A represents --CO--NH-- or --NH--CO--; and wherein A is in a para position relative to COOR 4 ; together with a pharmaceutically acceptable carrier or coating.
Claim 4
Dependent Claim
101 words
A pharmaceutical composition comprising an effective amount of a carboxylic acid compound represented by the following formula: ##STR4## wherein R 1 , R 2 , and R 3 independently represent a hydrogen atom or an alkyl group of at least two carbon atoms wherein at least two of R.sup., R 2 , and R 3 represent an alkyl group of at least two carbon atoms; R 4 represents a hydrogen atom or an alkyl group; A represents --CO--NH-- or --NH--CO--; and wherein A is in a para position relative to COOR 4 ; together with a pharmaceutically acceptable carrier or coating.
Claim 5
Dependent Claim
2 words
6-(3,4-Di-isopropylphenylcarbamoyl)pyridine-3-carboxylic acid.
Claim 6
Dependent Claim
2 words
6-(3,4-Di-isopropylphenylcarbamoyl)pyridine-3-carboxylic acid.
Claim 7
Dependent Claim
2 words
5-(3,4-Di-isopropylphenylcarbamoyl)pyridine-2-carboxylic acid.
Claim 8
Dependent Claim
2 words
5-(3,4-Di-isopropylphenylcarbamoyl)pyridine-2-carboxylic acid.
References Cited (Backward Citations)
WO1993006086A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1998-05-29 | 1998-11-28 | 1999-05-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2002-05-29 | 2002-11-28 | 2003-05-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2006-05-29 | 2006-11-28 | 2007-05-30 | $7700.00 | Window Closed / Lapsed |