US5444095A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Use of deprenyl to rescue damaged nerve cells
Assignee: University of Toronto
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Filing: 1994-02-28
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Granted: 1995-08-22
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Expires: 2014-02-28
Abstract
Abstract The present invention relates to the use of deprenyl or derivatives or analogues of deprenyl to rescue damaged nerve cells in an animal; to pharmaceutical compositions containing deprenyl adapted for such use; and, to methods for the treatment of disorders of the nervous system by rescuing damaged nerve cells.
Inventors
- 👤 William G. Tatton
- 👤 Carol E. Greenwood
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 15:40
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/26; A; A61; A61K; A61K31/00; A61K31/13; A61K31/135; A61K31/137; G; G01; G01N; G01N2500/00
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
65 words
A method for rescuing damaged nerve cells in a patient, comprising: administering to a patient having damaged nerve cells an amount of deprenyl, a pharmaceutically acceptable salt of deprenyl, or an ester of deprenyl such that rescuing of damaged nerve cells occurs in the patient wherein the patient has damage resulting from a condition selected from the group consisting of hypoxia, ischemia, stroke and trauma.
Claim 2
Independent Claim
65 words
A method for rescuing damaged nerve cells in a patient, comprising: administering to a patient having damaged nerve cells an amount of deprenyl, a pharmaceutically acceptable salt of deprenyl, or an ester of deprenyl such that rescuing of damaged nerve cells occurs in the patient wherein the patient has damage resulting from a condition selected from the group consisting of hypoxia, ischemia, stroke and trauma.
Claim 3
Dependent Claim
12 words
The method of claim 1 wherein deprenyl is administered to the patient.
Claim 4
Dependent Claim
11 words
The method of claim 2 wherein the deprenyl is (-) deprenyl.
Claim 5
Dependent Claim
10 words
The method of claim 1 wherein the patient is human.
Claim 6
Independent Claim
66 words
A method for rescuing damaged nerve cells in a patient, comprising: topically administering to a patient having damaged nerve cells an amount of deprenyl, a pharmaceutically acceptable salt of deprenyl, or an ester of deprenyl such that rescuing of damaged nerve cells occurs in the patient wherein the patient has damage resulting from a condition selected from the group consisting of hypoxia, ischemia, stroke and trauma.
Claim 7
Independent Claim
66 words
A method for rescuing damaged nerve cells in a patient, comprising: topically administering to a patient having damaged nerve cells an amount of deprenyl, a pharmaceutically acceptable salt of deprenyl, or an ester of deprenyl such that rescuing of damaged nerve cells occurs in the patient wherein the patient has damage resulting from a condition selected from the group consisting of hypoxia, ischemia, stroke and trauma.
Claim 8
Dependent Claim
12 words
The method of claim 5 wherein deprenyl is administered to the patient.
Claim 9
Dependent Claim
11 words
The method of claim 6 wherein the deprenyl is (-) deprenyl.
Claim 10
Dependent Claim
10 words
The method of claim 5 wherein the patient is human.
Claim 11
Independent Claim
85 words
A method for rescuing damaged nerve cells in a patient, comprising: administering to a patient having damaged nerve cells an amount of deprenyl, a pharmaceutically acceptable salt of deprenyl, or an ester of deprenyl such that rescuing of damaged nerve cells occurs in the patient wherein the patient has damage resulting from a condition selected from the group consisting of hypoxia, ischemia, stroke and trauma, wherein the deprenyl, a pharmaceutically acceptable salt of deprenyl, or an ester of deprenyl is the only active ingredient administered.
Claim 12
Independent Claim
85 words
A method for rescuing damaged nerve cells in a patient, comprising: administering to a patient having damaged nerve cells an amount of deprenyl, a pharmaceutically acceptable salt of deprenyl, or an ester of deprenyl such that rescuing of damaged nerve cells occurs in the patient wherein the patient has damage resulting from a condition selected from the group consisting of hypoxia, ischemia, stroke and trauma, wherein the deprenyl, a pharmaceutically acceptable salt of deprenyl, or an ester of deprenyl is the only active ingredient administered.
Claim 13
Dependent Claim
12 words
The method of claim 9 wherein deprenyl is administered to the patient.
Claim 14
Dependent Claim
11 words
The method of claim 10 wherein the deprenyl is (-) deprenyl.
Claim 15
Dependent Claim
10 words
The method of claim 9 wherein the patient is human.
Claim 16
Dependent Claim
12 words
The method of claim 1 wherein the patient is a non-human animal.
Claim 17
Dependent Claim
12 words
The method of claim 5 wherein the patient is a non-human animal.
Claim 18
Dependent Claim
12 words
The method of claim 9 wherein the patient is a non-human animal.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1998-08-21 | 1999-02-20 | 1999-08-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2002-08-21 | 2003-02-20 | 2003-08-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2006-08-21 | 2007-02-20 | 2007-08-22 | $7700.00 | Window Closed / Lapsed |