US5468544A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Composite materials using bone bioactive glass and ceramic fibers
Assignee: University of Pennsylvania
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Filing: 1993-11-15
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Granted: 1995-11-21
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Expires: 2013-11-15
Abstract
Abstract Composite materials formed from bone bioactive glass or ceramic fibers and structural fibers are disclosed. In preferred embodiments, a braid or mesh of interwoven bone bioactive glass or ceramic fibers and structural fibers is impregnated with a polymeric material to provide a composite of suitable biocompatibility and structural integrity. Most preferably, the mesh or braid is designed so that the bioactive fibers are concentrated at the surface of the implant to create a surface comprised of at least 30% bioactive material, thereby providing enhanced bone ingrowth. The interweaving between the bone bioactive glass or ceramic fibers and the core of structural fibers overcomes the problems found in prior composite systems where the bioactive material delaminates from the polymer. Preferred bioactive materials include calcium phosphate ceramics and preferred structural fibers include carbon fibers. Improved prosthetic implants and methods of affixing an implant are thus also disclosed.
Inventors
- 👤 Michele S. Marcolongo
- 👤 Paul Ducheyne
- 👤 Frank Ko
- 👤 William LaCourse
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 07:11
CPC Classifications
C; C03; C03C; C03C4/00; C03C4/0007; A; A61; A61F; A61F2/00; A61F2/02; A61F2/30; A61F2/3094; A61F2/30965; A61F2/32; A61F2/36; A61F2/3662; A61F2/367; A61L; A61L27/00; A61L27/02; A61L27/025; A61L27/10; A61L27/40; A61L27/42; A61L27/422; A61L27/44; A61L27/443; A61L27/446; C03C13/00; D; D03; D03D; D03D15/00; D03D15/20; D03D15/242; D03D15/267; D03D15/275; D03D15/50; D03D9/00; A61F2002/30001; A61F2002/30108; A61F2002/30199; A61F2002/30289; A61F2/30767; A61F2/30771; A61F2002/3082; A61F2230/00; A61F2230/0063; A61F2230/0091; C03C2213/00; C03C2213/02; D10; D10B; D10B2101/00; D10B2101/02; D10B2101/06; D10B2101/08; D10B2101/10; D10B2101/12; D10B2331/00; D10B2331/02; D10B2331/021; D10B2401/00; D10B2401/04; D10B2401/041; D10B2401/06; D10B2401/061; D10B2401/063; D10B2509/00; Y; Y10; Y10T; Y10T428/00; Y10T428/29; Y10T428/2913; Y10T428/2929; Y10T428/2931; Y10T428/2933; Y10T428/2964; Y10T428/2965; Y10T428/2967; Y10T428/2969; Y10T428/2973; Y10T428/2978; Y10T428/30; Y10T442/00; Y10T442/30; Y10T442/3049; Y10T442/3179; Y10T442/322; Y10T442/3228; Y10T442/3236
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
29 words
A biocompatible composite of tows of bone bioactive fibers comprising at least 19% Na 2 O by mole intermingled with tows of structural fibers in a non-bioabsorbable polymeric matrix.
Claim 2
Dependent Claim
29 words
A biocompatible composite of tows of bone bioactive fibers comprising at least 19% Na 2 O by mole intermingled with tows of structural fibers in a non-bioabsorbable polymeric matrix.
Claim 3
Dependent Claim
40 words
The composite of claim 1, wherein the bone bioactive fibers are arranged in a predetermined distribution and a section of a surface of the composite to be affixed to bone is comprised of about 30% or more bone bioactive fibers.
Claim 4
Dependent Claim
51 words
The composite of claim 2 wherein the composite comprises: (a) biocompatible structural fibers disposed within the interior of the composite, (b) biocompatible structural fibers interwoven with the bone bioactive glass or ceramic fibers, and (c) a surface section defining a section to be affixed to bone comprising the bone bioactive fibers.
Claim 5
Dependent Claim
13 words
The composite of claim 1 wherein the structural fiber is a carbon fiber.
Claim 6
Dependent Claim
21 words
The composite of claim 1 wherein the non-bioabsorbable polymeric material is chosen from the group consisting of: polysulfone; PEEK; and PEKK.
Claim 7
Dependent Claim
29 words
The composite of claim 1, wherein the bone bioactive fibers comprise 40-60% SiO 2 , 19-30% Na 2 O 10-21% CaO and 0-4% P 2 O 5 by mole.
Claim 8
Dependent Claim
29 words
The composite of claim 1, wherein the bone bioactive fibers comprise 45-55% SiO 2 , 19-30% Na 2 O, 15-20% CaO and 0-3% P 2 O 5 by mole.
Claim 9
Dependent Claim
29 words
The composite of claim 7, wherein the bone bioactive fibers comprise 52% SiO 2 , 30% Na 2 O, 15% CaO and 3% P 2 O 5 by mole.
Claim 10
Dependent Claim
17 words
The composite of claim 9 wherein the bone bioactive fiber has a diameter of about 5-25 microns.
Claim 11
Dependent Claim
11 words
The composite of claim 6 further comprising at least one modifier.
Claim 12
Dependent Claim
26 words
The composite of claim 10, wherein the modifier is chosen from the group consisting of: K 2 O; MgO; Al 2 O; and F 2 .
Claim 13
Dependent Claim
16 words
The composite of claim 9, wherein the bone bioactive fiber has a diameter between 10-13 microns.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1998-11-20 | 1999-05-22 | 1999-11-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2002-11-20 | 2003-05-22 | 2003-11-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2006-11-20 | 2007-05-22 | 2007-11-21 | $7700.00 | Window Closed / Lapsed |