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US5523054A Expired / Lapsed US ⏱️ 0.0 years remaining

Test element for quantitative NIR spectroscopic analysis

Assignee: Clinical Diagnostic Systems Inc
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Filing: 1995-01-31
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Granted: 1996-06-04
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Expires: 2015-01-31
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Abstract

Abstract There is disclosed a slide test element and method of assay that allows for detection of analytes in biological liquids without the use of any detection reagents. The method uses NIR spectroscopy and a test element comprising a support, and a substantially constant light-path defining layer comprising a diffusely-reflecting material that is a) sufficiently porous in all directions as to allow a liquid to spread uniformly in all directions, and b) homogeneously reflects at least 95% of NIR radiation.

Inventors

  • 👤 Steven C. Switalski
  • 👤 Thomas R. Kissel

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-08 10:16
CPC Classifications
B; B01; B01L; B01L3/00; B01L3/50; B01L3/508; G; G01; G01N; G01N21/00; G01N21/84; G01N21/8483; G01N33/00; G01N33/48; G01N33/50; G01N33/52; G01N33/525; G01N35/00; G01N35/02; G01N35/04; G01N35/10; G01N35/1002; G01N21/17; G01N21/25; G01N21/31; G01N21/35; G01N21/359

Claims Analysis

Total Claims: 2
Claim 1
Independent Claim 131 words
A test element for analyzing analytes in patient samples, comprising, in overlying relation, a support, and a substantially constant light-path providing layer consisting essentially of a diffusely-reflecting material that a) is sufficiently porous in all directions as to allow a liquid to spread uniformly in all directions, and b) homogeneously and diffusively reflects at least 95% of NIR radiation, said element being substantially free of: i) reagents capable of reacting with said analyte, and ii) a hydrophilic polymer layer that is both separate from said light-path providing layer, and has a thickness equal to or greater than 1 micron, and further including a mirror layer in-between said light-path providing layer and said support and in contact with said support, effective to increase the path length of NIR radiation through said layer.
Claim 2
Dependent Claim 131 words
A test element for analyzing analytes in patient samples, comprising, in overlying relation, a support, and a substantially constant light-path providing layer consisting essentially of a diffusely-reflecting material that a) is sufficiently porous in all directions as to allow a liquid to spread uniformly in all directions, and b) homogeneously and diffusively reflects at least 95% of NIR radiation, said element being substantially free of: i) reagents capable of reacting with said analyte, and ii) a hydrophilic polymer layer that is both separate from said light-path providing layer, and has a thickness equal to or greater than 1 micron, and further including a mirror layer in-between said light-path providing layer and said support and in contact with said support, effective to increase the path length of NIR radiation through said layer.

References Cited (Backward Citations)

US3992158A Cited
US4357363A Cited
US4582684A Cited
WO1993000580A1 Cited
EP0525550A1 Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1999-06-04 1999-12-04 2000-06-04 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2003-06-04 2003-12-04 2004-06-04 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2007-06-04 2007-12-04 2008-06-04 $7700.00 Window Closed / Lapsed

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