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US5523291A Expired / Lapsed US ⏱️ 0.0 years remaining

Injectable compositions for soft tissue augmentation

Assignee: Datascope Investment Corp
•
Filing: 1993-09-07
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Granted: 1996-06-04
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Expires: 2013-09-07
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Abstract

Abstract Injectable implant compositions for soft tissue augmentation comprise elastin and collagen and a biocompatible carrier. An injectable implant composition for soft tissue augmentation is derived from the ligamentum nuchae which has been treated to remove non-collagenous and non-elastinous proteins. Methods of making an injectable implant composition for soft tissue augmentation from the ligamentum nuchae are described.

Inventors

  • 👤 Ernst Janzen
  • 👤 Matthias J. Hoekstra
  • 👤 Richard P. Dutrieux

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-25 13:30
CPC Classifications
A; A61; A61K; A61K38/00; A61L; A61L27/00; A61L27/36; A61L27/3683; A61K38/16; A61K38/17; A61K38/39; A61L27/14; A61L27/22; A61L27/227; A61L27/26; A61L27/3641; A61P; A61P41/00; A61P43/00

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 32 words
An injectable implant composition for soft tissue augmentation derived from animal tissue, comprising elastin and collagen and a biocompatible carrier, said tissue having been comminuted to break up the natural collagen/elastin matrix.
Claim 2
Dependent Claim 32 words
An injectable implant composition for soft tissue augmentation derived from animal tissue, comprising elastin and collagen and a biocompatible carrier, said tissue having been comminuted to break up the natural collagen/elastin matrix.
Claim 3
Dependent Claim 24 words
A composition according to claim 1 wherein said elastin is at least 10% by weight of the combined dry weight of elastin plus collagen.
Claim 4
Dependent Claim 18 words
A composition according to claim 1 wherein said elastin is at least 50% of said combined dry weight.
Claim 5
Dependent Claim 18 words
A composition according to claim 1 wherein said elastin is at least 70% of said combined dry weight.
Claim 6
Dependent Claim 22 words
A composition according to claim 1 wherein said elastin and said collagen are derived, at least in part, from different tissue sources.
Claim 7
Dependent Claim 21 words
A composition according to claim 1 wherein said collagen and said elastin have been treated to remove noncollagenous and non-elastinous proteins.
Claim 8
Dependent Claim 13 words
A composition according to claim 1 wherein said collagen has not been cross-linked.
Claim 9
Dependent Claim 30 words
A composition according to claim 1 wherein said collagen has been cross-linked with a compound selected from the group consisting of hexamethylene diiosocyanate, a polyepoxy and a water soluble carbodiimide.
Claim 10
Dependent Claim 40 words
An injectable implant composition for soft tissue augmentation derived from animal ligamentum nuchae which has been treated to remove non-collagenous and non-elastinous proteins, comprising: collagen; and elastin, wherein said tissue has been comminuted to break up the natural collagen/elastin matrix.
Claim 11
Dependent Claim 40 words
An injectable implant composition for soft tissue augmentation derived from animal ligamentum nuchae which has been treated to remove non-collagenous and non-elastinous proteins, comprising: collagen; and elastin, wherein said tissue has been comminuted to break up the natural collagen/elastin matrix.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1999-06-04 1999-12-04 2000-06-04 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2003-06-04 2003-12-04 2004-06-04 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2007-06-04 2007-12-04 2008-06-04 $7700.00 Window Closed / Lapsed

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