US5599666A
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Allelic ladders for short tandem repeat loci
Assignee: Promega Corp
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Filing: 1994-03-28
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Granted: 1997-02-04
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Expires: 2014-03-28
Abstract
Abstract The present invention is directed to an assay system, a kit and a process for detecting at least one short tandem repeat sequence from DNA at a specific locus utilizing an allelic ladder containing at least two short tandem repeat sequences of the same lengths as two or more known alleles for the locus.
Inventors
- 👤 James W. Schumm
- 👤 Christoph Puers
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 10:35
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/68; C12Q1/6876; C12Q1/6881; C12Q1/6813; C12Q1/6827; C12Q1/6844; C12Q1/6858; C12Q2600/00; C12Q2600/156
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
68 words
An allelic ladder for evaluating short tandem repeat sequences at a specific locus wherein the locus and the minimum number of alleles in each ladder for each specific locus is selected from the group consisting of: HUMCSF1PO containing at least 9 alleles, HUMF13A01 containing at least 12 alleles, HUMFESFPS containing at least 8 alleles, HUMLPL (LIPOL) containing at least 7 alleles, and HUMVWFA31 containing at least 7 alleles.
Claim 2
Dependent Claim
68 words
An allelic ladder for evaluating short tandem repeat sequences at a specific locus wherein the locus and the minimum number of alleles in each ladder for each specific locus is selected from the group consisting of: HUMCSF1PO containing at least 9 alleles, HUMF13A01 containing at least 12 alleles, HUMFESFPS containing at least 8 alleles, HUMLPL (LIPOL) containing at least 7 alleles, and HUMVWFA31 containing at least 7 alleles.
Claim 3
Dependent Claim
15 words
An allelic ladder specific for the STR locus HUMHPRTB (HPRT-1) containing at least 12 alleles.
Claim 4
Dependent Claim
15 words
An allelic ladder specific for the STR locus HUMHPRTB (HPRT-1) containing at least 12 alleles.
Claim 5
Dependent Claim
105 words
A kit for analyzing short tandem repeat sequences from a DNA sample at a specific locus selected from the group consisting of HUMCSF1PO, HUMF13A01, HUMFESFPS, HUMLPL (LIPOL), HUMVWFA31, and HUMHPRTB (HPRT-1) comprising: a container containing an allelic ladder specific for the locus, wherein the allelic ladder for HUMCSF1PO contains at least 9 alleles, the allelic ladder for HUMF13A01 contains at least 12 alleles, the allelic ladder for HUMFESFPS contains at least 8 alleles, the allelic ladder for HUMLPL (LIPOL) contains at least 7 alleles, the allelic ladder for HUMVWFA31 contains at least 7 alleles, and the allelic ladder for HUMHPRTB contains at least 12 alleles.
Claim 6
Dependent Claim
105 words
A kit for analyzing short tandem repeat sequences from a DNA sample at a specific locus selected from the group consisting of HUMCSF1PO, HUMF13A01, HUMFESFPS, HUMLPL (LIPOL), HUMVWFA31, and HUMHPRTB (HPRT-1) comprising: a container containing an allelic ladder specific for the locus, wherein the allelic ladder for HUMCSF1PO contains at least 9 alleles, the allelic ladder for HUMF13A01 contains at least 12 alleles, the allelic ladder for HUMFESFPS contains at least 8 alleles, the allelic ladder for HUMLPL (LIPOL) contains at least 7 alleles, the allelic ladder for HUMVWFA31 contains at least 7 alleles, and the allelic ladder for HUMHPRTB contains at least 12 alleles.
Claim 7
Dependent Claim
27 words
The kit of claim 3 further comprising additional containers either each containing one primer of a primer pair or containing a primer pair for said specific loci.
References Cited (Backward Citations)
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| 3.5 Years (Year 4) | 2000-02-04 | 2000-08-05 | 2001-02-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2004-02-04 | 2004-08-05 | 2005-02-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2008-02-04 | 2008-08-05 | 2009-02-04 | $7700.00 | Window Closed / Lapsed |